PC Sheep Scab 2020 FINAL

Parasite Control leaflet series

ANIMAL HEALTH IRELAND Contributing to a profitable and sustainable farming and agri-food sector through improved animal health

Sheep Scab

PARASITE CONTROL PROGRAMME

Animal Health Ireland, 2-5 The Archways, Carrick-on-Shannon, Co. Leitrim, N41 WN27

AHI gratefully acknowledges the financial and other contributions of our stakeholders.

PCBCOI

Contributing to a profitable and sustainable farming and agri-food sector through improved animal health

Animal Health Ireland, 2-5 The Archways, Carrick-on-Shannon, Co. Leitrim, N41 WN27 Phone 071 9671928 Email nmorgan@animalhealthireland.ie

PAGE 3

Sheep Scab

What is sheep scab? Sheep scab is an allergic dermatitis caused by a reaction to the faeces of the scab mite, Psoroptes ovis (P. ovis) (Figure 1) and is characterised by sheep itching and scratching against objects such as fence posts, gates or walls or nibbling and/or biting at their fleeces . It is a welfare issue as sheep can spend a considerable portion of their time scratching and can also result in increased mortality rates in young lambs that are born to affected ewes. Sheep scab is a notifiable disease. If sheep scab is suspected or confirmed in a flock, the Department of Agriculture, Food and the Marine must be notified through the Veterinary Inspector at the Regional Veterinary Office. What are the clinical signs? In the initial stages of infestation, animals often appear clinically normal or they may be restless, have a discoloured fleece and show increased scratching behaviours. In later stages, animals become severely itchy and the intense rubbing and scratching can result in wool loss, skin thickening, scabbing and wounds. The intense itching can also result in a loss of condition due to decreased feed intake and secondary infections. When does the condition usually occur? The condition mainly occurs during the autumn and winter months. However, cases have also occurred during summer months, with lambs being particularly affected. What is the life cycle? P. ovis is a non-burrowing mite which lives on the skin of its host (sheep). Over a period of approximately 40 days, female mites lay one to two eggs per day. The life cycle from an egg to an adult takes approximately 14 days to complete and each development stage involves a moult which lasts 12 – 24 hours, during which time that particular life cycle stage does not feed. The mite population grows rapidly within 6-8 weeks after infestation, resulting in the observed clinical signs as described above.

Figure 1 . Sheep scab mite recovered from a wool sample.

www.animalhealthireland.ie

Please refer to the disclaimer on the last page regarding information in this leaflet.

PAGE 4

Sheep Scab

How does it spread? Sheep to sheep

Most commonly, it is transferred between sheep through direct contact. It is important to recognise that this mite can survive off the host and maintain infectivity for up to 16 days in buildings, on posts or gates where sheep have been itching and scratching or on sheep-handling equipment. As a result, other sheep may potentially become infested when rubbing against these same objects. Farm to farm Sheep scab can be spread from farm to farm through the purchase of infested sheep, many of which may be sub- clinically infested (not yet showing clinical signs of disease such as itching or scratching) or through the borrowing of sheep-handling equipment which has been used on infested sheep within the previous 16 days without adequate cleaning. The use of communal or shared grazing areas is also a potential risk factor for infestation when sheep from Although the species that affects cattle is considered to be the same species that affects sheep, there is limited transfer of the mite between cattle and sheep . Indeed, the scab mite strain that is found on sheep tends to feed on skin oils which contrasts with the mite strain found on cattle, where red blood cells form an important part of the diet. If it is suspected that cattle are affected by P. ovis , this should also be reported to the local Veterinary Inspector. How is sheep scab diagnosed? Sheep scab is commonly diagnosed based on clinical signs such as itching, scratching and nibbling. Other ectoparasites such as lice must also be considered when investigating the potential cause(s) of these clinical signs. To confirm a diagnosis, both skin scrapes and samples of wool should be collected from the edges of active lesions and examined for the presence of ectoparasites such as mites and lice. A blood test has been developed in the UK which can be used to detect sub-clinically infested animals. Antibodies detectable in blood are produced by the sheep from two weeks after exposure to the sheep scab mite. This test can be particularly useful, as in many cases purchased sheep that are not showing any clinical signs are a means of introducing this mite into a new flock. Animals that are brought onto a farm should be quarantined and treated if necessary, before mixing with the main flock to prevent spread of mites. Control and treatment It is important to recognize that although the entire life cycle of the scab mite is spent on the sheep, these mites can also survive off the host and maintain infectivity for up to 16 days . Thus, fields or sheds which previously housed sheep scab-infested animals can only be considered mite-free areas if these locations have been kept free of sheep for more than 16 days. The treatment of sheep scab involves the use of either dips (e.g. organophosphate-based diazinon or the synthetic pyrethroid cypermethrin) or injectable macrocyclic lactone anthelmintics (wormers) (e.g. ivermectin, doramectin and moxidectin). There are important differences in administering the treatment and the speed of action between dips and injectable treatments. There are also differences within the macrocyclic lactone wormer group as regards their persistence of action. These differences are outlined below in Table 1 below. affected flocks can potentially come into contact with sheep from unaffected flocks. Is there transfer of mites between cattle and sheep?

www.animalhealthireland.ie

PAGE 5

Sheep Scab

Plunge Dips (Pyrethroid/Organophosphate)

Wormers (Macrocyclic Lactones)

Dipping. Ensure that sheep are plunge- dipped for at least 1 minute with heads dipped under twice.

All macrocyclic lactones wormers used in the treatment of sheep scab are given by injection.

Route of administration

This varies depending on the product used. Only moxidectin has a persistence of greater than 16 days.

Most have persistence of activity of greater than 16 days.

Persistence

May take several days to kill the mites present. In addition, sheep may continue to itch for a number of days post- treatment until all mite faeces has been washed off the fleece.

Speed of action

Mites normally killed within 24 hours.

Potential to contribute to the development of gut worm resistance to wormers

Their use does not contribute to increasing the risk of gut worm resistance to wormers.

Their use in the control of sheep scab can inadvertently increase the risk of gut worm resistance to wormers.

Dips require precautions for safe handling and disposal for user health and safety and to prevent environmental contamination.

Standard handling and disposal of a medicinal product applies.

Health and safety

Table 1. Sheep scab control options.

What product should I use if I am returning sheep to a pasture or shed used by untreated sheep in the previous 16 days? In this case, it is advisable to use either a plunge dip or give a moxidectin injection. Both treatments will have a persistence of activity greater than 16 days, thereby outliving any potential mite challenge. Given that the persistence of both ivermectin and doramectin is shorter than 16 days, the use of either wormer in this scenario can result in the sheep becoming re-infested as the treatment effect will have waned within the period that mites can survive off the host animal. If using these wormers, it is advised to move sheep after treatment to a mite-free environment such as an area that has been free of untreated sheep for more than 16 days. If I treat sheep that have sheep scab with an injectable wormer (e.g. moxidectin, doramectin or ivermectin) what are the additional post- treatment considerations? Sheep treated with any of these three wormers must not be mixed with untreated sheep for a period of 14 days post- treatment unless those animals will also receive treatment. This is because there is a risk of potential mite transfer from affected to non-affected sheep due to the variable speeds of action of these wormers in killing sheep scab mites.

www.animalhealthireland.ie

PAGE 6

Sheep Scab

Mite Resistance to Treatment Cases of resistance to moxidectin by sheep scab mites have been reported in four flocks in the UK in 2018. As a result, it is advised that any cases of suspected treatment failure be fully investigated and reported to the manufacturer so that the extent of true resistance can be fully established, whilst also ruling out other common causes of treatment failure (e.g. poor administration technique, inappropriate product choice).

www.animalhealthireland.ie

PAGE 7

Sheep Scab

TECHNICAL WORKING GROUP James O’Shaughnessy (Chairman) - DAFM, Veterinary Laboratory Services, Charles Chavasse - Zoetis, Bosco Cowley - MSD Animal Health, Martin Danaher - Teagasc Food Research Centre Ashtown, Theo de Waal - UCD School of Veterinary Medicine, John Gilmore - Veterinary Practitioner, Barbara Good - Teagasc, Athenry, Fintan Graham - Veterinary Practitioner, Ian Hogan - DAFM, Veterinary Laboratory Services, Orla Keane, - Teagasc, Grange, Mark McGee - Teagasc, Grange, Grace Mulcahy - UCD School of Veterinary Medicine, Mark Robinson - Queen’s University, Belfast, Maresa Sheehan - DAFM, Veterinary Laboratory Services. TECHNICAL WORKING GROUP RAPPORTEUR Natascha Meunier - Animal Health Ireland

INTELLECTUAL PROPERTY All images contained in this leaflet are the property of AHI, or have been included with the permission of the owner. Please seek permission from AHI if you wish to use these images and provide the correct attribution of ownership when reproducing them. If reusing any other material in this leaflet, please attribute AHI as the source. IMPORTANT NOTICE - DISCLAIMER This leaflet is issued and shall be read only on the basis that it will not be relied upon by any person as a basis for any act or omission or otherwise without obtaining professional veterinary and health and safety verification and advice and that no liability or responsibility to any person is accepted or shall be incurred, and no recourse or claim by any person will be made, by or against AHI,any stakeholder, collaborator, officer, agent, subcontractor or employee of AHI, any member of the Technical Working Group, any contributor to, author, publisher, distributor, reviewer, compiler or promoter of or any other person in respect of or in connection with the leaflet or the contents thereof or any matter omitted therefrom.

No representation or guarantee is given, whether by AHI or any other such person, that the contents of this information leaflet are comprehensive, up to date, or free from error or omissions, nor that the advice provided is appropriate in every particular circumstance. The contents of this information leaflet are not intended to be a substitute for appropriate direct advice from your veterinary practitioner. Appropriate veterinary and health and safety advice should be taken before taking or refraining from taking action in relation to the animal disease dealt with in this information leaflet. The contents of this leaflet may be updated, corrected, varied or superseded from time to time by later publications or material on the AHI website and reference should be made to that website accordingly. Any references in this booklet or links in the AHI website to external websites or other resources are provided for convenience only and the contents thereof are not to be considered as endorsed thereby.

2-5 The Archways, Carrick-on-Shannon, Co Leitrim N41 WN27. Phone 071 9671928 Email nmorgan@animalhealthireland.ie Web www.animalhealthireland.ie

www.animalhealthireland.ie

Page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7

Made with FlippingBook Ebook Creator