Product Fluorescent Probes: Functionalized Probes Functionalized fluorescent probes Azide functionalized fluorescent probes allow copper-catalyzed click chemistry reactions with other molecules containing “acceptor” functional groups such as an alkyne. Azide functionalized fluorescent probes
Maleimide offers a selective and efficient method to attach the fluorescent probe to molecules containing a thiol functional group. Maleimide is particularly useful for conjugating the probe to proteins or peptides with cysteine residues. Maleimide functionalized fluorescent probes
DBCO functionalized fluorescent probes allow for copper-free click chemistry with other molecules containing a “donor” functional group such as an azide. DBCO functionalized fluorescent probes
These fluorophores feature an activated NHS ester moiety which is extremely reactive with nucleophiles such as amines. NHS esters are capable of reacting with amines in mild alkaline conditions without further activation. Applications of these probes include fluorescent tagging of peptides or proteins. NHS functionalized fluorescent probes
Free acid functionalized fluorescent probes Free acid functionalized fluorescent probes have a carboxylic acid moiety capable of reacting with primary amines to form stable amide bonds.
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