The Business Review December 2020

Suite Of Solutions If there is going to be a global eradication of the virus, it will require investments in the logistics and supply chain, as well as preparation by clinics and healthcare workers to administer tests and vaccines and engaging with their communities so that they understand and trust what they are receiving. “Our holy grail is cheap, effective and ideally single dose,” says Mark Suzman, CEO of the Gates Foundation, during a video briefing. “Both for the price—it’s half as expensive— but also efficiency. You don’t have to track people coming back for a second dose, and it should be hopefully relatively easy to manufacture.” What distinguishes Covid-19 from other vaccine and public health initiatives is the sheer volume. “We’re talking about vaccinating everybody, or at least 70% of everybody, which is still probably 10 billion doses,” says Suzman. “Just a reminder, even the existing vaccines are not yet proven safe and efficacious for children or pregnant mothers or others, so we may need a second wave of vaccines…That’s why continuing these investments is so important.” Another issue is mistrust in the vaccines, fueled by conspiracy theories, something the foundation has dealt with before, particularly regarding contraceptives and childhood vaccines. “It’s been disheartening to see the disinformation because it does create vaccine hesitancy,” says Gates. “One reason is that more people are at home; they’re anxious for good reason because of Covid, they’re reading, and they’re getting fed disinformation. We’re going to have to have a reckoning when this is all over about how you put some good regulations on social media platforms so that disinformation isn’t spread so easily. Disinformation causes more deaths.” But community role models may be even more meaningful than a digital clean-up, says Gates, adding: “More than likely, once people start to see healthcare workers taking the vaccine, elderly people, teachers taking it and getting back to some semblance of normal life, people are going to talk to their doctor and decide if it makes sense for them and more than likely so they can get back to living life in a more normal way.” What Happens Next The foundation has not identified specific partners or grantees yet but has previously funded international organizations for infectious disease and immunotherapy work, such as GAVI, the Vaccine Alliance, as well as private biotechnology companies, such as BioNTech. According to the foundation, it has funded $16 billion for the discovery, development and delivery of life-saving vaccines through 2019. “We can be capitalistic as a philanthropy, and we can take some riskier investments, but this execution really requires pulling together the public and private sector,” says Suzman. “And it’s worth noting and remembering that

Melinda Gates: “I know how scary this disease can be.”

the U.S. has historically been the global leader in healthcare efforts like this.” The Gates have had ongoing conversations with Sen. Mitch McConnell and Rep. Nancy Pelosi, and are waiting for the Biden administration to take office for further discussions. “We will be looking on a case-by-case basis where the greatest needs are and where there are opportunities,” Suzman continues. He predicts that where the foundation goes, others will follow. “A lot of what we’re trying to do is get support from other partners. And to the extent our work can be sort of seed funding that accelerates or helps crowdsource others.” Within days of the news of the U.S. Covid-19 breakout— with the first case recorded in Seattle, home of the Gates Foundation, on January 20—Bill and Melinda Gates were aware of the threat. “We were getting information and starting to say, ‘Oh, gosh, how quickly is this thing going to go?’” she recalls. After 20 years working in public health and infectious diseases, this time their mission came close to the hearth and heart. “We have two close friends in March who had family members who had Covid,” Gates says. “I was in touch with both people multiple times a day. It was terrifying to see what their families were going through. I know how scary this disease can be.” n

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December 2020 | The Business Review

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