Riley Children's Health Annual Report – October 2025

Allergy and immunology specialists at Riley Children’s Health are expertly trained in the management and treatment of pediatric allergy, asthma and immunology concerns. Our board certified physicians offer the latest diagnostic methods and treatments delivered in a safe and comfortable manner to children dealing with the challenges of allergy and immunology conditions. ALLERGY & IMMUNOLOGY

RESEARCH HIGHLIGHTS

NOTABLE PUBLICATIONS

■ Riley Children’s participates in PARK (Preventing Asthma in High Risk Kids), a multicenter clinical study led by the National Institute of Allergy and Infectious Diseases to investigate the impact of omalizumab to prevent severe asthma and new allergies in preschool-age children. ■ We are involved in multiple clinical trials and studies investigating the role of the airway microbiome in the development of allergic disease.

Annals of Allergy, Asthma and Immunology: May 2024 Decoding viral infections and risk for asthma: Biomarkers or clinical histories? Lead author: Kirsten M. Kloepfer, MD The Journal of Allergy and Clinical Immunology, In Practice: February 2025 Efficacy and safety: Safety of epicutaneous immunotherapy in peanut-allergic toddlers: Open-label extension to EPITOPE Blood: January 2025 One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying them OUR TEAM ALSO PUBLISHED IN: Science Immunology American Journal of Human Genetics

TOP DISTINCTIONS

Specialized programs

High-Risk Asthma Program This collaborative program addresses the medical and social needs of children and families with severe asthma. > Learn more. Gastrointestinal Eosinophilic Digestive Diseases Program Our multidisciplinary program allows children to see a pediatric allergist, gastroenterologist and dietitian during the same visit. Immune Dysregulation Program This program combines experts from rheumatology, immunology, hematology and infectious diseases to guide children with complex immune disorders. Immunogenetics Program Children with complex immune disorders receive the latest guidance from an immunologist, a geneticist and a genetic counselor.

■ Recognized for distinction in clinical care by Food Allergy Research and Education (FARE); performs more food challenges than any other program in Indiana ■ Indiana’s only multidisciplinary program for eosinophilic gastro- intestinal diseases ■ Member of the Jeffrey Modell Centers Network for treatment and research related to primary immunodeficiency diseases

Riley Children’s is a core member of the Severe Pediatric Asthma Consortium, a group focused on developing best practice guidelines and cultivating research initiatives.

■ Partners with the Indiana Department of Health to

Program Volume: 2023 – 2024

Allergy patient visits

Immunology patient visits 2023 745 2024 805

Oral food challenges

analyze all abnormal newborn screenings for severe combined immune deficiencies (SCIDs)

2023 5,680 2024 6,851

2023 389 2024 381

Professional organization affiliations American Academy of Pediatrics – Section on Allergy and Immunology Girish V. Vitalpur, MD, FAAP, FAAAAI American Academy of Allergy, Asthma & Immunology Jay J. Jin, MD, PhD, FAAAAI Simran K. Jutla, MD Kirsten M. Kloepfer, MD, MS, FAAAAI Nurcicek Padem, MD, MS Craig D. Sewell, DO Girish V. Vitalpur, MD, FAAP, FAAAAI

DIRECTOR Girish V. Vitalpur, MD, FAAP, FAAAAI Professor of Clinical Pediatrics, IU School of Medicine > Connect with Dr. Vitalpur on Doximity.

The inpatient penicillin allergy de-labeling protocol at Riley Children’s is used in hospitals across Indiana.

Clinical Immunology Society Jay J. Jin, MD, PhD, FAAAAI Nurcicek Padem, MD, MS

6 board certified physicians

See full team member list >

Annual Report 2024 – 2025

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