RESEARCH HIGHLIGHTS
NOTABLE PUBLICATIONS
RILEY HEART CENTER
Home to a high-volume, nationally ranked pediatric cardiology program, Riley Children’s Health delivers the full continuum of cardiac care from fetuses and premature infants to adults with congenital heart disease. Achieving exceptional patient outcomes, the Riley Heart Center has experienced significant growth in recent years. In addition to offering specialists in every clinical area of cardiology, we are active in research to address unmet needs in pediatric cardiology. CARDIOLOGY
■ Enrolling in the multicenter study of the Renata Minima growth stent, the only FDA-approved stent for treating infant vascular stenosis ■ Actively involved in the multicenter study: The ACTION VAD registry: A collective five-year experience related to improving outcomes in pediatric heart failure ■ Cardiac developmental biology study investigating the role of thromboxane-prostanoid receptor in Friedreich’s ataxia Benjamin J. Landis, MD , is the principal investigator of a $3.3 million National Institutes of Health (NIH) grant to identify new genetic and echocardiographic imaging markers that improve the risk stratification and advance the mechanistic understanding of thoracic aortic aneurysm progression. NIH-FUNDED STUDIES R01: Modeling mortality in Duchenne muscular dystrophy cardiomyopathy: Identification of surrogate outcome measures for DMD drug trials R01: Lrp5 and Lrp6 signaling in bone mechanotransduction and metabolism
The Journal of Clinical Investigation: July 2024
Early ascertainment of genetic diagnoses clarifies impact on medium term-survival following neonatal congenital heart surgery Digestive and Liver Disease: August 2024 Biomarkers of fibrosis and portal hypertension in Fontan-associated liver disease in children and adults World Journal for Pediatric and Congenital Heart Surgery: February 2025 Conduit size, branch pulmonary artery size and
Premier programs
TOP DISTINCTIONS
Fetal Cardiology Program Partners in the Fetal Center, our cardiologists offer in-depth diagnostic imaging, evaluation and consultation during pregnancy. Cardiac Psychology Program Inpatient and outpatient program offers assessment and psychotherapeutic intervention for patients coping with acute or chronic heart conditions, procedures, and emergent events/trauma.
Cardiovascular Genetics Program Fully integrated CV genetics program provides testing, evaluation and consultation for the full spectrum of heritable heart conditions. Preventive Cardiology Program Cardiologists with expertise in preventive cardiology diagnose and manage both inherited and acquired dyslipidemia and pediatric hypertension (partner with pediatric nephrology for ambulatory blood pressure monitoring).
■ National leader in patient outcomes with mortality rates below benchmark* ■ Integrated care model with subspecialty care coordination and novel approaches to cardiac intensive care, inpatient navigation and home monitoring ■ Only formalized comprehensive adult congenital heart disease program in Indiana; program accredited by the Adult Congenital Heart Association ■ Continued program expansion with specialized programs in pediatric cardiac psychology, preventive cardiology and a new offering in cardio-oncology ■ Statewide outreach across 12 locations with exponential annual growth ■ Accredited by the Intersocietal Accreditation Commission and a member of the Cardiac Neurodevelopmental Outcome Collaborative
36 research publications in 2024
reoperation in patients with truncus arteriosus
2,985
Fetal Echocardiogram Volume: 2020 – 2024 Performed at
2,764
2,569
2,307
1,927
eight locations across Indiana
Average annual growth rate 12.4%
2020
2021
2022
2023
2024
Echocardiogram Interpretations: 2020 – 2024 Our program serves more than 40 Indiana hospitals and achieves record volume.
DIVISION CHIEF Larry W. Markham, MD, FAAP, FACC, FAHA Phillip Murray Professor of Pediatric Cardiology; Professor, Departments of Pediatrics and Medicine, IU School of Medicine > Connect with Dr. Markham on Doximity.
24,371 25,561
22,726
New visit volume average: 35% of total Riley Cardiology Volume: 2020 – 2024
21,177
16,205
17,887
14,479
12,964
12,649
9,821
Average annual growth rate 7.5%
Average annual growth rate 9.8%
34 board certified physicians
See full team member list >
* Source: Society of Thoracic Surgeons (STS) Table 16, Harvest Report, published December 2024 for period ending June 30, 2024
4,636 4,608 5,329
3,791 4,725
2020
2021
2022
2023
2024
New patient visits
Total visits
2020
2021
2022
2023
2024
Annual Report 2024 – 2025
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