RESEARCH HIGHLIGHTS
CARDIAC CRITICAL CARE MEDICINE RILEY HEART CENTER
■ Founding member and coordinating center: Collaborative Research in Pediatric Cardiac Intensive Care (CoRe-PCIC) network; more than 30 U.S. sites participating in several ongoing research projects ■ Riley Children’s is part of the Pediatric Cardiac Critical Care Consortium (PC4), which uses registry data from more than 60 congenital heart programs to evaluate best practices and drive improvements. ■ In 2024, the cardiac critical care team was actively enrolling in prospective observational cohort studies and clinical trials focused on multiorgan dysfunction (including acute respiratory distress syndrome, sepsis, renal failure and ECMO support).
The expert cardiac critical care physicians at Riley Children’s Health provide specialized care for critically ill newborns, infants, children and adolescents with congenital and acquired heart disease. Our high-acuity, high-volume CVICU includes 23 beds for CVICU patients and an eight-bed specialized neonatal ICU.
Advanced technologies and procedures
TOP DISTINCTIONS
■ Ventricular assist devices (VAD) – We offer a wide range of circulatory support devices to support patients in bridge-to-transplant or bridge-to-recovery circumstances. ■ Continuous renal replacement therapy (CRRT) – In addition to a multidisciplinary CRRT program, Riley Children’s offers aquapheresis to remove excess fluid accumulation in critically ill neonates and children. ■ Etiometry software – All CVICU rooms are equipped with this FDA-approved software visualization application to collect, store and present ICU data in near real time.
■ Only program in Indiana to offer pediatric heart transplantation and mechanical circulatory support capability ■ Indiana’s only pediatric hospital with a formal extracorporeal cardiopulmonary resuscitation (ECPR) program
Postoperative Severity – Adjusted CVICU Length of Stay Riley Children’s 9.47 days All PC4 ** facilities 11.1 days
NOTABLE PUBLICATIONS
World Journal for Pediatric and Congenital Heart Surgery: July 2024 Deep sedation in pediatric patients with single ventricle physiology outside of the operating room Shock: July 2024 Novel echocardiogram analysis of cardiac dysfunction is associated with mortality in pediatric sepsis; Lead author: Developing a generalizable pediatric ECMO emergency checklist for clinical specialist: Progress and challenges Resuscitation: February 2025 Evaluating post-cardiac arrest blood pressure thresholds associated with neurologic outcome in children: Insights from the pediRES-Q database Pediatric Critical Care Medicine: May 2024 Cardiac surgery-associated AKI in neonates undergoing the Norwood operation: Retrospective analysis Daniel T. Cater, MD Perfusion: April 2025
Major Complications – Unadjusted Riley Children’s 17.2 All PC4 ** facilities 23.3
■ Riley Children’s is designated a Platinum Level Center of Excellence by the Extracorporeal Life Support Organization. ■ Over the past five years, our overall survival rate for ECMO patients is higher than 60% (above the national average). ■ To date, Riley Children’s has treated more than 1,200 patients with ECMO.
High-volume pediatric ECMO center
Risk-adjusted CVICU Surgical Mortality *
Risk-adjusted CVICU Medical Mortality *
Any Postoperative Complication – Unadjusted
4.00%
24.7
2.77%
2.66%
2.07%
Riley Children’s
34.9
Riley Children’s All PC4 ** facilities
Riley Children’s All PC4 ** facilities
All PC4 ** facilities
Additional outcome measures
DIRECTOR Riad Lutfi, MD Professor of Clinical Pediatrics, IU School of Medicine > Connect with Dr. Lutfi on Doximity.
ALTERNATIVE COMPLICATIONS
CASES
OUT OF
RILEY CHILDREN’S
ALL PC4 ** FACILITIES
CLABSI per 1,000 line days (central line-associated bloodstream infection) CAUTI per 1,000 catheter days (catheter-associated urinary tract infection)
0.88 per 1,000
5
5,679
1.13 per 1,000
0 per 1,000
0
1,453
0.75 per 1,000
Unplanned extubation per 100 ventilator days
10 board certified physicians (plus multiple board certified neonatologists and physicians in other specialties)
0.36 per 100
See full team member list >
13
3,628
0.26 per 100
SSI per 100 surgical procedures (surgical site infection)
0.40 per 100
3
755
1.43 per 100
Chart reflects July 1, 2023 – June 30, 2024, outcomes.
* Risk adjustment is a methodological approach incorporating unique patient characteristics that impact patient outcomes and are unrelated to the quality of care delivered by the care team or hospital. ** Pediatric Cardiac Critical Care Consortium | Charts reflect July 1, 2023 – June 30, 2024 , outcomes.
Annual Report 2024 – 2025
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