Riley Children's Health Annual Report – October 2025

RESEARCH HIGHLIGHT

“We have found that kids with VUR and UTIs have more genetic variations in urinary tract protection genes, which could be a possible source of their UTIs. Through the study, we also discovered that kidney function changes did not correlate to dimercaptosuccinic acid scan findings, suggesting that perhaps we are using the wrong test to study this issue.”

David S. Hains, MD, MBA Division Chief, Nephrology, Riley Children’s Health Byron P. & Francis D. Hollett Professor of Pediatrics, IU School of Medicine > Connect with Dr. Hains on Doximity.

TRAILBLAZERS Pediatric nephrologists at Riley Children’s Health have uncovered new findings about kidney damage in children with vesicoureteral reflux (VUR). Challenging a decades-old standard, the research team discovered that a commonly used test to evaluate the impact of recurrent urinary tract infections (UTIs) on the kidneys may not be the best method.

More about nephrology at Riley Children’s Riley Children’s is home to the nation’s first comprehensive neonatal kidney health program. > Learn more about our program.

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READ about the findings published in a letter in JAMA Pediatrics .

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