www.neuroendocrinecancer.org.uk
Neuroendocrine Tumours (NETs): NETs are well-differentiated cancers, meaning they may retain some of their original features.
However, they can show different rates of growth, from slow (Grade 1) to rapid (Grade 3) – see diagram:
Neuroendocrine Carcinomas (NECs): NECs are poorly differentiated cancers, meaning they have lost many, if not all, of their original features. These cells divide and grow rapidly. NECs do not have the same surface proteins (receptors) that are found in NETs, and therefore, the treatment and management plans differ from those used for NETs. Many NET cells have proteins (receptors) on their surface that can be targeted to aid in diagnosis and treatment. These proteins are called somatostatin receptors (SSTRs).
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