www.neuroendocrinecancer.org.uk
How is radiation used in Radioligand Therapy?
Radioactive isotopes are produced by placing isotopes into a nuclear reactor, where they are exposed to radiation. Once they become radioactive, they are stored within the reactor in protective capsules. This is necessary because, once removed from the reactor, the radioactivity begins to decrease or decay. When needed, the radioactive isotopes are taken out of the reactor and undergo a series of safety and quality checks, both before and after they are attached to the targeting molecule (ligand).
Once this process is completed, the radioligands are shipped to the treating hospital for use.
Since the radioactivity starts to decrease from the moment they are removed from the reactor, transportation must happen quickly—typically within 72 hours from the reactor to the patient. Radioligands can be safely transported by air (commercial or cargo), often completing their journey by courier via road transportation to ensure timely delivery.
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