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BIOS 380 - Advanced Microbiology Same as BIOS 282 Microbiology, with the additional requirement of microbial isolation and identification of field and clinical samples. An 8-10 page research paper and presentation on one of these isolations is also required. Lecture/Lab Hours: Three hours lecture, four hours laboratory. Prerequisite(s): CHEM 105 or Discusses the mechanisms of integration and homeostasis at the cellular, organ and system levels. Muscular, neural, vascular, excretory, and endocrine interactions are studied. Variations between vertebrate groups are presented. Includes a major research project. Lecture/Lab Hours: Three hours lecture, four hours laboratory. Prerequisite(s): BIOS 112 and BIOS 114 or BIOS 254; CHEM 106 or CHEM 112. Fee: Lab $75. Unit(s): 4. CHEM 112. Fee: $75. Unit(s): 4. BIOS 382 - Vertebrate Physiology BIOS 390 - Au Sable Institute of Environmental Studies Au Sable is a Christian institute focusing on field studies from a stewardship perspective. Biola is a participating member of the institute. Courses are taught at field stations in Michigan, Washington, Florida and India. Coursework taken through the institute can be counted as elective credit in the Biological Sciences, or may be substituted for specific major requirements. Prerequisite(s): Upper division standing. Note(s): May be repeated with different content for a maximum of 16 units. Unit(s): 4. BIOS 401 - General Ecology An introduction to the general concepts of the ecology of populations, communities and ecosystems, including physiological ecology, speciation and evolutionary theory. Laboratory includes field trips and a research project. Prerequisite(s): BIOS 100 and BIOS 110 or BIOS 112 and BIOS 114. Fee: Lab $75. Unit(s): 4. BIOS 402 - Parasitology Taxonomy, life history, physiology, ecology, and morphology of animal parasites with emphasis on those affecting humans. Lecture/Lab Hours: Three hours lecture, four hours laboratory. Prerequisite(s): BIOS 100 and 110, or BIOS 112 and 114. Fee: Lab $75. Unit(s): 4. BIOS 410 - Topics in Environmental Science Selected topics in environmental science. Prerequisite(s): Upper division standing and consent. Note(s): May be repeated with different content for a maximum of 8 units. Au Sable or Pacific Rim offering. Unit(s): 1-4. BIOS 411 - Biochemistry I Structures and properties of biomolecular components of cells: including proteins, carbohydrates, lipids, nucleotides, nucleic acids, vitamins and coenzymes, kinetics and mechanism and regulation of enzymes action in biological systems. Prerequisite(s): BIOS 312; CHEM 302. Unit(s): 3. BIOS 412 - Biochemistry II Mathematical treatment of bioenergetics emphasizing major concepts and problem solving; principles of metabolic processes. Prerequisite(s): BIOS 312; CHEM 302. Unit(s): 3. BIOS 413 - Laboratory in Biochemistry A laboratory course to accompany BIOS 411, BIOS 412 (CHEM 411, CHEM 412). The isolation, characterization and analysis of bimolecular including the use of biochemical instrumentation and methodology for work in protein structure, enzymology, metabolism and genetics. Prerequisite(s): BIOS 411 or CHEM 411. Fee: Lab $75 each semester. Unit(s): 2. BIOS 430 - Topics in Natural Resource Management Selected topics in natural resource management. Prerequisite(s): Upper division standing. Note(s): May be repeated with different content for a maximum of 8 units. Au Sable or Pacific Rim offering. Unit(s): 1 - 4.

BIOS 431 - Developmental Biology Analyzes the molecular, genetic and cellular mechanisms which control development of body form and specialized cell types from a single fertilized egg, and which maintain stable differentiated states in the adult. Laboratory emphasizes gametogenesis, vertebrate embryology, histology and directed experimental manipulation of embryos. Lecture/Lab Hours: Three hours lecture, four hours laboratory. Prerequisite(s): BIOS 312. Fee: Lab $75. Unit(s): 4. BIOS 440 - Topics in Advanced Biology Selected topics of current interest and concern are studied. Note(s): Course may be repeated with different content (section title). This course only for BIOS, BHIB, BCHM and BIES majors. Unit(s): 3 - 4. BIOS 444 - Ornithology Systematics, distribution, physiology, behavior and ecology of birds. Field identification emphasized. Lecture/Lab Hours: Two hours lecture, four hours laboratory / field trip. Saturday field trips are required. Prerequisite(s): BIOS 100 and BIOS 110 or BIOS 112 and BIOS 114. Fee: Lab $75. Unit(s): 3. BIOS 445 - Immunology A study of the structures and functions of the immune system, humoral and cell mediated immunity and analysis of medically significant disorders of the immune system. Lecture/Lab Hours: Three hours lecture, four hours laboratory weekly. Prerequisite(s): BIOS 281 or BIOS 282 or BIOS 312 or BIOS 382. Unit(s): 4. BIOS 450 - Directed Research Literature and laboratory or field research of a specific subject or technique in biology; advanced students gain experience in experimental design, laboratory investigation and technical writing. Prerequisite(s): Junior or Senior biological science major standing. Note(s): Requires a written report. Fee: Lab $75. Unit(s): 1 - 4. BIOS 455 - General Virology Virology is a course that examines the diversity of plant, animal and bacterial viruses. Emphasis on topics such as: molecular interactions between the host and virus, the genetics and chemical nature of viruses and the replication strategies of viruses. How viruses caused disease, how they are used in biotechnology and their overall impact on society will also be discussed. Bacteriophage and tissues culture techniques will be stressed in laboratory. Lecture/Lab Hours: Three hours lecture, four hour laboratory. Prerequisite(s): BIOS 111 and BIOS 113, BIOS 282 or BIOS 380. Fee: $75. Unit(s): 4. BIOS 460 - Clinical Observation Practicum • Pre-Medical Practicum • Pre-Dental Practicum • Pre-Medical Technology • Pre-Veterinary Practicum Practicum: A professionally supervised observation, demonstration and study in a local medical, dental or laboratory facility. Introduction to health care philosophies, hospital and patient routines, personnel, instrumentation and specific treatment practices. Prerequisite(s): Junior standing. Note(s): Case study and research paper required. Thirty hours of observation. Fee: Insurance $20. Unit(s): 1. BIOS 470 - Seminar in Advanced Biology Literature research followed by oral presentation, group discussion and evaluation; independent thought and study stressed. Prerequisite(s): Junior or Senior biological science major standing. Note(s): May be repeated for a maximum of 2 units. Unit(s): 1. BIOS 480 - Internship Professionally supervised participation in a research project at a laboratory facility or an industry. Documentation of the time spent and the activities performed as well as a written paper explaining the project are required. Prerequisite(s): Junior standing. Note(s): A minimum of thirty hours of involvement. May be repeated for a maximum of 2 units. Unit(s): 1.

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