RNSH Surgery & Anaesthesia Research Activity Report 21-22

TRAUMA Head of Department: Geoff Healy

RESEARCH SUPERVISION (2021-2022)

Brian Burns • 2 MD Programme Students, Sydney University • 1 Honours Project, Notre Dame University • 2 MD Programme Students, Macquarie University

DEPARTMENTAL RESEARCH RESOURCES

CLINICAL DATABASES TO SUPPORT OUTCOMES RESEARCH • ITIM NSW Trauma Registry • Aeromedical Operations NSW Ambulance Air Maestro Database

CURRENT NSLHD HUMAN RESEARCH ETHICS APPLICATION (HREA) APPROVALS • A Multi-centre randomised, double-blinded, placebo-controlled trial of pre-hospital treatment with tranexamic acid for severely injured patients at risk of acute traumatic coagulopathy (PATCH- Trauma Study) • Efficacy and value In ExpeDited out of hospital arrEst care with rnd tidal CO2 (ETCO2) ECMO CPR (ECPR) - the EVIDENCE Study LINKS TO TRANSLATIONAL RESEARCH PARTNERS OR UNIVERSITY DEPARTMENTS • NHMRC Clinical Trials Centre, University of Sydney • NZ Lottery, Grants Board Translational Research Project • Intensive Care Foundation, Research Grant • Health Research Council of New Zealand, Research Grant

CURRENT RESEARCH ACTIVITY

• Out of hospital cardiac arrest-rural vs metropolitan incidence and outcomes • iCa levels in severe trauma-transfused versus not transfused • Systematic review prehospital fibrinogen concentrate and whole blood transfusion • Efficacy and value in ExpeDited out of hospital arrEst care with end tidal CO2 (ETCO2) ECMO CPR (ECPR) • Pre-hospital treatment with tranexamic acid for severely injured patients at risk of acute traumatic coagulopathy

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