RNSH Surgery & Anaesthesia Research Activity Report 21-22

ANAESTHESIA (INCLUDES: ALLERGY CLINIC AND ACUTE PAIN MANAGEMENT) Head of Department: Ben Olesnicky and Jonothon Brock

DEPARTMENTAL RESEARCH RESOURCES

CLINICAL DATABASES TO SUPPORT OUTCOMES RESEARCH • Allergy/Australian and New Zealand Anaesthetic Allergy Group • Trauma • Perioperative Medicine • Perioperative Allergy Database

CURRENT NSLHD HUMAN RESEARCH ETHICS APPLICATION (HREA) APPROVALS • Validation of a scoring tool for suspected peri-operative immediate hypersensitivity reactions using case referrals to Royal North Shore peri-operative Allergy Clinic • Skin testing - in vitro testing and drug provocation testing for diagnosis and management of drug allergy LINKS TO TRANSLATIONAL RESEARCH PARTNERS OR UNIVERSITY DEPARTMENTS • Department of Immunology • Australian and New Zealand Anaesthetic Allergy Group (ANZAAG)

CURRENT RESEARCH ACTIVITY

Clinical Trials • Chewy - chewing gum versus ondansetron for post-operative nausea and vomiting in women and girls having laparoscopic or breast surgery • MASTERSTROKE - Management of Systolic blood pressure during Thrombectomy by Endovascular route for acute ischaemic STROKE • Investigation of massive transfusion practice and development of an experimental clinical decision support system • The feasibility of implementing a validated fatigue risk management system for Junior Medical Staff on nightshift • Long-term Outcomes of Lidocaine Infusions for PostOperative Pain (LOLIPOP) • Orthostatic hypotension in the post anaesthesia care unit as a predictor for delayed mobilisation post lower limb arthroplasty • Validation of a scoring tool for suspected peri-operative immediate hypersensitivity reactions using case referrals to Royal North Shore peri-operative Allergy Clinic • Perioperative analgesia for major abdominal surgery • Opioid neuraxial analgesia for major open abdominal surgery: a feasibility study using a combination of intrathecal and epidural morphine • Rib fracture intervention study

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