Step 1 Finding the Problem “Homing” to Injury Sites
Imagine you have a team of firefighters stationed all over a city, waiting for an emergency call. In your body, stem cells act like these firefighters, constantly looking for distress signals. When you have an injury, inflammation, or tissue damage, your body releases chemical distress signals (inflammatory markers like cytokines and chemokines). These signals tell stem cells where help is needed. Stem cells detect these signals and begin migrating (“homing”) to the site of injury or inflammation. Once the stem cells arrive, they don’t just replace damaged cells. Instead, they act more like coaches, guiding and instructing other cells to repair the tissue. They do this through paracrine signaling, which is a fancy way of saying they send out growth factors, cytokines, and extracellular vesicles (like exosomes) that tell surrounding cells what to do. Step Communicating with the Body “Paracrine Signaling” 2
Think of it like a construction crew: Stem cells
project managers, guiding the repair process.
Growth factors & cytokines
project blueprints and tools, instructing damaged tissues to rebuild., guiding the repair process.
Exosomes
messengers, delivering important instructions to other cells.
Through this signaling, stem cells reduce inflammation, promote healing, and stimulate the body's natural repair mechanisms.
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