Writing and Publishing Scientific Articles Course Workbook

Writing and Publishing Scientific Articles

8-12

Figure 8. Effect of budesonide on the methylation of the Igf-II gene. The methylation status of the CpG sites in the DMR2 of the Igf-II gene is depicted. The numbers above the circles give the location of cytosines in the CpG sites. Open circles indicate unmethylated sites, and filled circles indicate methylated sites. The numbers at the start of the strings of circles are the identification numbers of the mice. The numbers in parentheses after animal number 8-245 identify the 2 tumors from that animal. (Figure from Tao L et al. Effect of budesonide on the methylation and mRNA expression of the insulin - like growth factor 2 and c-myc genes in mouse lung tumors. Mol Carcinog 35:93 – 102, 2002. Copyright © 2002 John Wiley & Sons, Inc. Reprinted by permission of Wiley-Liss, Inc., a subsidiary of John Wiley & Sons, Inc.; legend adapted. Only panel A is shown; panel B and its accompanying legend have been omitted.)

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