Writing and Publishing Scientific Articles
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gain. . . . In the malignant insulinoma of patient 24, FISH again detected different cell populations with the chromosome 9 probes. In addition to a major population with four copies of both centromere 9 and 9q34, 25% of the nuclei demonstrated a clear duplication of the c-abl target at 9q34. In addition, a number of very large nuclei were observed in between these nuclei containing two sometimes very large centromere spots together with up to 12 9q34 signals (Fig. 2B), suggesting that amplification of this target had occurred. The frequency of these cells (5%) was, however, much too low to identify this amplification as such by CGH. (Adapted with permission from Speel EJ et al. Genetic evidence for early divergence of small functioning and nonfunctioning endocrine pancreatic tumors: gain of 9Q34 is an early event in insulinomas. Cancer Res 61:5186 – 5192, 2001.)
Suggested Structure of the Results Section
In the Results section, report the findings for each experiment described in the Methods section. As much as possible, the order in which the findings are presented in the Results section should be the same as the order in which the corresponding experiments are described in the Methods section. Subheadings are a useful way to organize material in the Results section. In some cases, especially in basic science articles, the subheadings in the Results section can correspond 1 to 1 with the subheadings in the Methods section — in other words, you can use the same subheadings in Methods and Results. However, it is not always possible to use this technique.
For basic science articles, sometimes you can organize subsections of the Results section as follows:
▪ Begin with a phrase or sentence that reminds readers of the experiment or analysis you performed. ▪ Describe the findings from that experiment or analysis, referring to figures and tables as appropriate. ▪ Close with a sentence that indicates what is most important about the data you have just presented.
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