What is the suggested dose of bromelain? There is no standard dose for bromelain. Recommended dosing generally ranges between 80 and 320 mg/day but because it is relatively nontoxic, daily doses up to 2000 mg have been used. Since the proteolytic activity (and therefore the medicinal effect) of bromelain can degrade based on storage conditions and processing of pineapples, it is not practical to substitute bromelain supplements with oral consumption of raw pineapple fruit. [20] Even though it’s extracted from pineapple, eating pineapple or drinking its juice doesn’t provide a large enough dose.
HYDROXYMETHYLBUTYRATE (HMB) – ENHANCING RECOVERY BY PRESERVING MUSCLE FUNCTION
What is HMB? Hydroxymethylbutyrate (HMB) is an active metabolite of the essential amino acid leucine. HMB is found in very small amounts in foods such as avocado, citrus fruit, cauliflower, and catfish. [21] HMB is made from leucine in the muscle and liver cells but only 5% of the leucine is converted to HMB, yielding very small amounts (0.2-0.4 grams in a 70 kg person) on a daily basis. How does surgery alter muscle function? The surgical stress response results in whole-body catabolism (breakdown of complex molecules to smaller ones). This is seen principally as the wasting of muscle, releasing amino acids to allow the synthesis of proteins known as acute phase reactants and production of glucose needed as an energy source. [10] In addition, perioperative fasting can worsen the surgical stress response, weaken gut function, and amplify protein losses.
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