Journal of the Louisiana State Medical Society
R adiology C ase of the M onth
49-Year-Old Female With an Anterior Mediastinal Mass
Bruce Bordlee Jr., BS; Andrew Oncale, BS; Jonathan Stone, MD; Enrique Palacios, MD; Harold Neitzschman, MD
Castleman’s disease is an uncommon benign lymphoproliferative disorder characterized by hypervascular lymphoid hyperplasia. Two distinct histologic variants of Castleman’s disease exist – hyaline vascular type and plasma cell type. The etiology is uncertain; however, it is thought to be inflammatory or hamartomatous in nature. Castleman’s disease can occur at any age with a peak incidence in the third to fourth decade. This article presents a case of Castleman’s disease in a female patient and aims to educate about the natural his- tory, diagnosis, and management of the disease.
Figure 1A
Figure 1: CT post-contrast (A) axial, (B) coronal, and (C) sagittal planes demonstrating a well marginated non-enhancing solid mass in the anterior portion of the superior mediastinum. No evidence of lymphadenopathy or any other significant findings.
Figure 1B
78 J La State Med Soc VOL 166 March/April 2014
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