JUNE 2024 NEUROENDOCRINE CANCER UK QUARTERLY NEWSLETTER

NICE recommends SIRT Therapy for neuroendocrine tumours

It means that certain members of our community will now have access to a treatment that could positively impact on both the control of their disease and their quality of life Nikie Jervis, Support Service and Education Lead at Neuroendocrine Cancer UK

We are delighted to share with you the news that NICE has recommended SIRT (selective internal radiation therapy) for the treatment of neuroendocrine tumour-related liver metastases. procedures guidance [IPG786]: Selective internal radiation therapy for neuroendocrine tumours that have metastasised to the liver: Published 16th May 2024 NICE Interventional

What is SIRT and what does this mean for our community?

SIRT is a radiotherapy treatment that targets tumours within the liver, that cannot be safely removed through surgery. It is sometimes also called radio- embolisation or Trans Arterial Radio- Embolisation (TARE). It can be used for primary liver cancers or for cancer that has spread to the liver from another site. For example: liver metastases from a primary bowel neuroendocrine tumour. The aim of SIRT is to stop or significantly slow the growth of cancer. The additional benefit that may be seen in neuroendocrine tumours, is that it may also reduce some of the hormone- associated symptoms that are caused by the tumours. e.g., Carcinoid Syndrome. SIRT may be performed alone or in combination with other therapies.

It is a local therapy, meaning it only treats cancer cells near where it is administered. When used to target liver tumours, it does not treat other sites of disease outside of the liver. SIRT (selective internal radiation therapy) takes advantage of the fact that the liver gets its blood supply from 2 sources: the Hepatic Artery and the Portal Vein.

CLICK HERE to read the full article on our website.

We also recently held a special Webi-Natter on this subject and the recording will be available on our website shortly.

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www.neuroendocrinecancer.org.uk

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