Providing Complete Genomic Datasets Need complete datasets with no missing data for genomic selection or genome-wide association study (GWAS)? Khufu uses reference panel free imputation. This means markers are imputed from the data itself. Khufu does not require any up-front reference panel generation cost. s There is no need for design costs or customization. The per sample cost is only constrained by the genome size of the species s Khufu does not require a minimum sample commitment and is flexible for any project size
Taking Peak Performance to Another Level
Khufu uses low coverage, short-read sequencing data to provide genotyping results at a fraction of the normal cost.
At HudsonAlpha, we understand what is required to meet your needs with reliable and accurate results that are delivered on time. We are here to help guide your through the data so it is understandable at each step in the process and you’ll be ready to take action. Khufu provides extremely accurate single-nucleotide polymorphisms (SNP) identification using very low coverage sequence data. In order to map traits to genes, the DNA sequences of the plants being studied must be lined up against a reference genome. When focusing on complex plant genomes, It is hard for currently available software to map short DNA reads to a reference genome and accurately identify molecular markers like SNPs that correlate with an observed trait. Khufu is effective in genotyping small or large numbers of plants, regardless of the population structure or the genome complexity.
The peak occurs at the genetic location of the SNP that is correlated to the trait.
We hope that by offering other researchers the ability to use this low-cost, highly accurate computational software, we can help to advance genomic research in many different fields.
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