Oasis Product Brochure 2023

Are you ready to embrace a new era of Nuclear Medicine and PET? Look no further. This product brochure outlines Oasis and key features within the applications. Enjoy the numerous pages and please email us with any questions you may have! Demos@segamicorp.com

OASIS

TAKE CONTROL OF YOUR WORKFLOW.

2023 EDITION

Benfits of Oasis

SEGAMI

Oasis Configuration

Segami was founded in 1995 in Columbia, Maryland to develop and market affordable, best-in-class, workstations for the Nuclear Medicine and Radiology markets. Selling via distributors and OEM channels, Segami has become a respected firm with a proven solution in the molecular imaging world. Segami’s flagship software molecular imaging solution, Oasis, is a vendor-neutral solution that seamlessly connects to Gamma Cameras, and Picture Archiving & Communication Systems (PACS). Oasis is built on a modern scalable architecture with flexible licensing and upgradability which integrates seamlessly with existing Nuclear Medicine, PET, and Cardiac cameras to make it easier than ever to incorporate into clinical practice. With Oasis's innovative features, it empowers nuclear medicine physicians and technologists to provide the highest level of care to their patients and ultimately improving patient outcomes and quality of life.

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TABLE OF CONTENTS

Benefits of Oasis Oasis Configuration

03 General Nuclear Medicine 04 Lung Applications 05 Cardiac Applications 08 Cedars - Third Party 09 Corridor 4DM - Third Party 10 SPECT/CT/MR 11 PET/CT/MR 13 Neruology Applications 15 CerQuant 15 NeuroGam 16 SISCOM 17 DaTScan 19 Schedule a Demo 20

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Segami Corporation

Benefits of Oasis

All in one Reading & Processing Station

Clinically Superior Segami is proud to employ the industry's most talented individuals, each with a passion for nuclear medicine and highly clinically experienced within the field. You can rest easy knowing that you are in the hands of true industry experts who understand the unique demands and challenges of nuclear medicine departments and workflows. Whether you need assistance with Oasis or have questions about your workflow, Segami’s support and training staff is always ready to provide you with the highest level of service and support. Experience the peace of mind that comes with Segami's unparalleled expertise.

Oasis allows physicians to interpret all Nuclear Medicine studies on a single platform. No more shuffling between different systems - with Oasis, everything you need is in one place. This unique capability not only saves time, but also enhances accuracy, which ensures that every study is handled with the utmost care and precision. High End Diagnostic Tools Seamlessly fuse Nuclear Medicine, SPECT, or PET volumes with CT or MRI. Oasis's high end diagnostic tools can help your facility to achieve high-quality results without the need for high-end equipment such as a PET-MR scanner. Our fusion tools improve diagnostic accuracy and clinical outcomes. Upgrade to Oasis and experience the future of multi- modality fusion.

Cost Effective

Since Oasis is a vendor neutral software, it can also help your healthcare facility save a significant amount of money. By using Oasis, your site can eliminate the need for expensive vendor-specific hardware, software, and even expensive cameras such as a PET-MR. Utilizing Oasis eliminates the requirement for all of those costly maintenance and upgrades fees. Oasis is simply an investment in your facility's future, offering a cost-effective and user-friendly solution for your nuclear medicine imaging needs.

Vendor Neutral

Oasis gives complete functionality to process and review Nuclear Medicine and PET scans, regardless of the camera vendor. Say "goodbye" to the constraints of specific camera workstations and say "hello" to the limitless potential of Oasis. With our innovative technology, you will have the flexibility to choose the camera vendor that is right for your facility, all while enjoying the highest level of performance and reliability with Oasis.

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Oasis | Page 01

Benefits of Oasis

User Friendly

Give new Life to an older Camera Update your current diagnostic systems to ensure high-quality performance without major capital equipment expense. This solution allows you to integrate older camera systems into your existing DICOM network. Optionally, you can use our processing software to bring your system up to date in respect to the latest level of clinical applications Uniform Processing By providing uniform processing, Oasis enables healthcare professionals to do all their qualitative and quantitative analysis on one platform. Oasis gives the healthcare professionals the latest clinical tools for assessing patient images despite different camera vendors. Customizable Whether you need to adapt the software to your existing workflow, integrate it with other systems, or need specific layouts, Oasis offers unparalleled flexibility and customization. Through Oasis, nuclear medicine reading and processing is fully customizable, offering healthcare professionals the flexibility to tailor it to their specific needs.

Oasis is designed to be user-friendly and intuitive, ensuring maximum efficiency and accuracy in your diagnostic procedures. Oasis is also specifically engineered to simplify complex nuclear imaging processes, allowing medical professionals to perform their tasks with ease and speed. The best part is that with Oasis, both novice and experienced users can easily navigate and perform tasks effortlessly. Training Efficiency Eliminate the need for training on multiple vendor workstations and reading stations. With Oasis, physicians, technologists, and other clinical staff can receive efficient processing and reading training all on one platform. Save time and resources while ensuring the highest level of training quality with Segami's Oasis. Robust Architecture The Oasis Client/Server architecture provides an efficient infrastructure for data and application management that can flawlessly be integrated into a PACS system.

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Oasis | Page 02

Oasis Configuration

Oasis can be interfaced with all gamma cameras and PET scanners serving within the Nuclear Medicine and Radiology markets. The DICOM images are sent from the Camera(s) and scanners to the PACS.

Nuclear Medicine Camera

PET/CT Camera

Note: A PACS system is not required for Oasis Standalone mode

PACS will then send the images to the Oasis server. These images and studies can be accessed, processed, and viewed with an Oasis workstation within or connected to the healthcare facility or hospital's network system, this also includes PC workstations, home offices, and laptops

Oasis Server

PACS Server

Laptop

Hospital / Healthcare Facility

Home Office

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Oasis | Page 03

General Nuclear Medicine Applications Oasis is an innovative platform that offers an extensive range of diverse and comprehensive general nuclear medicine applications. These organ-based applications encompass the full gamut of procedures routinely performed in nuclear medicine, making Oasis an indispensable tool in the arsenal of medical professionals seeking to optimize their diagnostic capabilities and deliver the highest level of patient care.

Planar Application list:

Bone scan Gastric Esophageal (Dynamic) Gastric emptying GI Bleed Hepatobiliary MUGA (Gated Bloodpool) Parathyroid Lung Analysis (Ventilation/Perfusion) Renal Renal Morphology (DMSA)

Salivary Gland Sentinel Node Shunt Analysis Thyroid

THE SECRET BEHIND THIS TRAVEL

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Lung Applications

Planar Lung Quant displays 2D ventilation and perfusion images, and allows quantification of the distribution of ventilation and perfusion in sections of the lung.

Key Features:

Analysis of Ventilation, Perfusion, or Ventilation + Perfusion. Static image displays of all acquired orientations. Display functions: window leveling, color scale selection, zoom, pan, magnify, colorize, measurement tool. Automatic 6-segmental quantification of anterior and posterior images. Generation of geometric mean images. Customized layouts through display script.

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Lung Applications

Lung SPECT performs reconstruction, registration, displays 3D volumes from ventilation and perfusion SPECT/CT imaging, and creates reprojection (pseudo planar) images. Lung SPECT also provides lung segment and FEV1 (Forced Expiratory Volume) quantification.

Key Features :

Data processing is entirely semi-automatic allowing user to manually draw template- based lung segments. Reconstruction performed using iterative reconstruction. Transverse, Coronal, Sagittal Slices, and MIP volumes. Pseudo-Planar images extracted from SPECT. Provides Lung segment and FEV1 (Forced Expiratory Volume) quantification. Display of Ventilation and Perfusion SPECT/CT studies. Display functions: Registration of Ventilation and Perfusion SPECT/CT studies, triangulation and window leveling.

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Lung Applications

PULMOGAM contains functionality that was developed in conjunction with the University of Lund in Sweden. This application provides detailed quantification of the difference between perfusion and ventilation in lung SPECT studies.

Key Features:

Standardized orthogonal slice displays.

LUND quantification that automatically generates

Automatic correction of hotspots Ventilation and Perfusion scans. Compatible with Technegas and aerosols. Ventilation/Perfusion Ratio images ideal for identifying potential areas of Pulmonary Embolism. Pseudo-Planar images extracted from SPECT. Automatic registration of

Distance weighted maximum intensity projections (MIP). Visual evaluation of segmental and sub-segmental mismatch with high sensitivity and specificity. Customized layouts through display scripts. in ventilation and perfusion images.

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Cardiology Applications

is Oasis's comprehensive, vendor-neutral cardiac SPECT and SPECT/CT reconstruction application. The application is ultra-fast, taking advantage of the computer’s GPU for fully 3D implementation based on a true OSEM3D algorithm, which includes "resolution recovery" also known as "collimator deblurring". CardiacREquant uses the complete image volume in the iterative reconstruction procedure in order to increase the image quality & therefore improves the clinical reliability, diagnostic confidence and interpersonal diagnostic reproducibility. CardiacREquant

Includes Automatic Correction for:

Attenuation Correction. Scatter Correction. Depth-dependence of the point-spread function (PSF), thus reducing the collimators blur by pre-filtering the projections according to the frequency-distance principle. Statistical noise, acting on the measured projections with a secondary regularization technique. To improve gated wall motion analysis, the application uses Fourier analysis which resamples to 16-time bins in each projection angle to improve the projection quality and applies tail-drop correction in the event the patient’s heart rate varies during the acquisition. Data may be motion corrected using Cedars-Sinai motion correction module. The volume can be masked to eliminate extra cardiac activity, reoriented, and zoomed. The reconstructed series can then either be saved to the database or directly sent to third-party applications (Cedars or Corridor4DM) for quantitative analysis.

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Third Party Options for SPECT, SPECT/CT, and PET/CT Cardiac Quantitative Analysis is a third-party application for review and analysis of myocardial perfusion studies, developed by Cedars-Sinai Medical Center. CSMC Cardiac Suite is fully integrated with Oasis and includes Quantitative Gated SPECT (QGS), an interactive application for the automatic segmentation, quantification and wall motion analysis of gated myocardial perfusion SPECT/PET. Quantitative Perfusion SPECT (QPS) is an interactive application for the automatic segmentation, quantification, analysis and display of static (non- gated) short-axis myocardial perfusion SPECT/PET images. Quantitative Blood Pool SPECT (QBS) provides automatic segmentation and quantification of gated blood pool (red blood cells, RBC), SPECT. Cedars Cardiac Suite

https://www.thecardiacsuite.com/ To find out more information about Cedars, please visit their website:

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Third Party Options for SPECT, SPECT/CT, and PET/CT Cardiac Quantitative Analysis SPECT and/or PET is an optional third party application intended to provide processing and multidimensional diagnostic review displays of reconstructed cardiac emission tomography studies. 4DMSPECT is a comprehensive cardiac application designed to review and quantitatively analyze cardiac myocardial perfusion and gated blood pool SPECT nuclear medicine studies. Corridor 4DM

https://www.inviasolutions.com/ To find out more information about Corridor4DM, please visit their website:

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SPECT/CT/MR The SPECT/CT applications allow for the loading of several types of studies and datasets including SPECT reconstruction, SPECT tomo, CT, MRI, Statics, Whole Body images, Flows, Blood Pools, and Screen Captures. For the datasets that are loaded, the application provides both SPECT and CT multi-planar reformation projections (consisting of linked Transverse, Coronal, and Sagittal views) used for triangulation. The application will also render one or more MIP derived from the SPECT data and provide a set of fusion images. Reconstructed tomographic data will be shown in a combination of cine and splash pages. The application also generates individual SPECT pages, each devoted to a single orthogonal projection. Oasis comes equipped with a set of clinical applications for review and analysis of SPECT/CT studies. Separate applications are provided for multiple different SPECT/CT or SPECT/CT/MR protocols with each containing an array of settings for scaling, color, and layouts. Up to 4 SPECT/CT scans can be loaded simultaneously for comparison purposes.

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Key Features: Standard orthogonal slice displays . Display functions: triangulation, window leveling, color scale selection, slice alignment, cine controls, zoom, pan, magnify, colorize, measurement tool. User definable CT window presets. Distance weight maximum intensity projections (M.I.P.). Measurement tools . Fusion display mode based on variable alpha

blending and /or variable thresholding.

Manual registration adjustment (translations, rotations). 3D region analysis based on iso-contouring. Automatic registration. Study comparison (follow-up). User definable hotkeys for commonly used functions. Dedicated lesion, linking, and registration managers. Compatible with all SPECT and hybrid SPECT/CT

scanner models.

Customized layouts though display scripts. Attenuation Correction. Scatter Correction. Depth-dependence of the point-spread function (PSF), thus reducing the collimators blur by pre-filtering the projections according to the frequency-distance principle. Statistical noise, acting on the measured projections with a secondary regularization technique.

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PET/CT/MR

Oasis PET/CT package is a unique package of applications for the Diagnostic Review of Volumetric Multi-Modality Data, compatible with data from all major vendors. These application make reading PET studies effortless with Automatic co-registration by using Mutual Information Algorithms or manually register these PET,CT, MR and/or SPECT images despite being acquired on different modalities. The integrated Lesion Manager in the PET/CT application allows users to track tumor size and tumor activity over time. Up to 4 PET/CT studies can be loaded at one time for comparison purposes. By establishing a strong correlation between areas of interest and the CT scan's precise anatomical reference, it amplifies the physician's capacity to accurately ascertain the location of functional activity.

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Key Features:

Standardized Uptake Value (SUV) provided in Minimum, Maximum, Average, Peak, and Total Lesion Glycolysis (TLG) values, calculated by 3 popular methods including Body Weight, Lean Body Mass or Body Surface Area. Powerful quantification options to manage disease and track lesions over time including all SUV values mentioned above, SUV Max, % change, and metabolic and anatomic volumes. Provides innovative response assessments such as PERCIST. Dedicated lesion, linking, and registration managers. Keyboard shortcuts (hotkeys) for tool functions and windowing settings. User definable CT window presents and image layouts with multi-monitor support. Multi-study comparison and auto-linking (up to 4 studies). QPET calculation. Crosshairs bound across all views, fully triangulated views including MIP views. Fusion display with alpha blending. Easily save fused images back to the server and PACS. Save sessions, VOIs, rulers.. and much more back to PACS. Save results and images in JPEG/BMP format. Support for advanced workflows such as "Head and Neck" and "Melanoma." Real time image scrolling. Easily customizable. Full resolution whole body display.

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Neurology Applications

Oasis is a Multimodality Brain Quantification software application that uses affine registration to the Montreal Neurological Institute atlas and provides quantitative/qualitative displays and comparison to multiple normative databases to measure the extent and severity of defects in over 100 functional areas of the brain. CerQuant

Key Features:

Currently validated with FDG. Offers Right to Left comparison. Uses templates for PET and SPECT while using automatic affine registration, with manual adjustments available. Patient’s brain is registered to the Montreal Neurological Institute’s atlas of functional regions. Patient brain is compared to 20 normal subjects closest in age. Five normalization methods available. 3D surface rendering display of results, with color-coded standard deviation from normal databases. Slice display with color-coded standard deviation derived from a database of normal subjects. In-depth quantification is provided, including Z-scores for Hypo, Healthy, and Hyper regions, defects in functional areas, and Right/Left asymmetry index, which can be exported to Excel. Fusion with MRI data; if the patient does not have an MR series, a template is used. The creation of normative databases based on normal subjects acquired at your site at no additional charge.

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Neurology Applications

The comprehensive package for visualizing and quantifying functional brain SPECT or PET images. NeuroGam allows differential analysis of studies by using an automatic registration algorithm which transforms the images into a standard atlas. NeuroGam application is a

Key Features:

Review and quantitative analysis of Brain Perfusion SPECT or PET studies.

Study comparison (baseline/activation, Diamox protocol, follow-up) with normalized.

Subtraction displays.

Automatic affine transformation into a stereotactic atlas (Talairach). Standardized orthogonal slice displays. Display functions include triangulation, window leveling, color scale selection, slice

alignment, cine controls, zoom, pan, magnify, colorize.

Cortical perfusion mapping on 3D surface images. Normal database comparison for HMPAO, ECD, FDG. Predefined structures: arterial terrains, and Brodmann areas for quantitative analysis. Compatible with most acquisition protocols.

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Neurology Applications

, a cutting-edge medical imaging technique involving a unique combination of SPECT and MRI. By leveraging this advanced approach, medical professionals can significantly enhance their ability to diagnose and accurately pinpoint areas of regional activation in the brain during seizure episodes. SISCOM, or Subtraction Ictal SPECT co-registered to MRI, captures high-quality images and pinpoints the specific area of the brain that is involved in seizure activity by utilizing the transient focal increase in cerebral blood flow. This powerful diagnostic tool is complemented by two distinct semi-quantitative analysis methods, including SPECT and PET registered to MRI (and even CT in the absence of an MRI series), providing a comprehensive and versatile approach to analyzing complex medical data. SISCOM

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Key Features:

Registration of ictal and interictal SPECT volume images. Comparison of Ictal and Inter-ictal SPECT images.

Automatic co-registration of SPECT images with MRI. Image subtraction is performed, creating delta images that highlights areas of seizure foci.

Fusion results are created with the delta images and MRI representing the regions of focal activation. Displays precise anatomic location of seizure focus prior to surgery. Optional masking to exclude areas of excess extracranial activity. Standard deviations available for the delta images. User preference subtraction threshold value. Determine the statistically significant regions of activation from the subtraction SPECT image. PET images are mirrored and subtracted, resulting in delta images that demonstrate significant differences in tracer metabolism.

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Neurology Applications

Key Features:

DaTscan

The

application

enables swift and efficient differentiation between essential tremor and tremor due to various Parkinsonian syndromes, including idiopathic Parkinson’s disease, multiple system atrophy, and progressive supranuclear palsy, by loading PET or SPECT scans to generate highly precise and accurate quantitative results.

Review of DATscan studies. Computation of binding potentials. Ability to rotate the volume for precise reconstruction. Saturation level adjustment. Chang attenuation available with adjustable coefficient. Counts of the of Putamen and Caudate Nucleus structures. Partial volume correction.

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Oasis can be found creating functional solutions throughout the world!

Want to see how Oasis can improve your workflow?

Schedule a Demo with a highly clinically trained specialist at:

www.Segamicorp.com

or email us at:

Demos@SegamiCorp.com

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