Cerebrum Fall 2021

CGRP- Targeted Therapies for Migraine

Brand Name and Drug

Treatment, Prevention, or Both

How Administered

Therapy Type

Dosage

AIMOVIG (Erenumab-Aooe)

Prevention

Subcutaneous injection

Monoclonal antibodies (mAb)

One or two shots (70 mg) per month

AJOVY (Fremanezumab)

Prevention

Subcutaneous injection

mAb

One shot (225 mg) per month or three shots (675 mg) every three months Two shots (120 mg each) the first month; one shot per month thereafter

EMGALITY (Galcanezumab- gnim) VYEPTI (eptinezumab- jjmr)

Prevention

Subcutaneous injection

mAb

Prevention

Intravenous infusion

mAb

100 mg IV every three months

NURTEC ODT (rimegepant)

Acute treatment; prevention Acute treatment

Pill form

gepant

One 75 mg pill once every other day

UBRELVY (Ubrogepant)

Pill form

gepant

50 or 100 milligrams (mg) per day, as needed

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