Cortisol Cortisol is another hormone that can be to blame for sleeping difficulties and constant tiredness. Cortisol is produced by the adrenal glands and regulated by the hypothalamus and the pituitary gland. Released during times of stress, cortisol is the trigger for your body’s “fight or flight” response to stressors.
However, cortisol does far more than that. It is also used to increase the metabolism of glucose, control blood pressure and reduce inflammation. Synthetic forms of cortisol are often used to treat inflammatory conditions and skin conditions. If you are suffering from a hormonal imbalance restricting the release of cortisol, you might feel constant tiredness, nausea, unexplained weight loss and muscle weakness.
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