Advancing Science and Treatment Innovation
NEALS member sites have collectively led and contributed to hundreds of ALS clinical trials, paving the way for new therapies and care models. Their involvement spans pivotal studies including trials for tofersen , edaravone , AMX0035 , Healey ALS MyMatch , and the HEALEY ALS Platform Trial – an innovative adaptive platform trial design that is reshaping how ALS treatments are evaluated. Many serve as lead or coordinating sites in multi-center studies and publish findings in peer- reviewed journals, advancing trial design and methodology. These sites have also played key roles in launching expanded access programs, expanding investigational treatment opportunities for people living with ALS. NEALS investigators have helped guide the design and implementation of these programs across the ALS field, bringing clinical trial expertise to ensure that expanded access pathways are ethical, scientifically informative, and aligned with ongoing therapy development. Innovating in Care and Community Engagement Embedded within local ALS care systems, many NEALS sites uniquely blend research with compassionate, multidisciplinary care . They support patient education, navigation, and communication regarding research opportunities, while local leadership fosters inclusion of underrepresented populations through targeted regional outreach.
Visit the NEALS website to find a NEALS site near you: https://neals.org/about/neals-member-sites
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