Tsolekile , Ncediwe (PhD)
Mrs Tsolekile was born in Cape Town, South Africa and holds a MSc Chemistry (Cum Laude) from the University of the Western Cape. She enrolled for a PhD (part-time) at the University of Johannesburg in 2015 and is currently a lecturer at the Cape Peninsula University of Technology. Mrs Tsolekile’s doctoral study addressed the short comings of porphyrins in cancer treatments. The study developed ecofriendly methods for the synthesis of CuInS based quantum dots (QDS) which were conjugated to both Neutral (mTHPP) and anionic (TPPS 4 ) porphyrins. The QDs-porphyrin conjugates showed improved properties compared to the porphyrin alone. Exposure of various cancerous and healthy cell lines to the conjugates, showed dose dependent results. The application of photodynamic therapy (PDT) on metastatic melanoma cells showed that the conjugate (QDs-porphyrin) exhibited excellent PDT efficacy. The candidate has published 11 peer reviewed journal articles, attended international research exchange programs, and presented her work at local and international conferences. Supervisor: Prof SO Oluwafemi Co-supervisor: Prof SP Songca (University of KwaZulu-Natal) Co-supervisor: Prof M Matoetoe (Cape Peninsula University of Technology)
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