2026 Express Scripts National Preferred Formulary

Drug Class

Excluded Medications

Preferred Alternatives

HEMATOLOGICAL (continued) Erythropoiesis-Stimulating Agents

ARANESP, EPOGEN, MIRCERA

PROCRIT, RETACRIT

IXINITY, RIXUBIS NOVOSEVEN RT

BENEFIX

SEVENFACT

ADVATE, ADYNOVATE, AFSTYLA, ALTUVIIIO, ELOCTATE, ESPEROCT, JIVI, KOGENATE FS, KOVALTRY, NOVOEIGHT, XYNTHA, XYNTHA SOLOFUSE

Factor Deficiency Agents & Related Products

NUWIQ, RECOMBINATE

REBINYN

ALPROLIX, IDELVION

FYLNETRA, NEULASTA, NYVEPRIA, ROLVEDON, RYZNEUTA, STIMUFEND, UDENYCA GRANIX, NEUPOGEN, NYPOZI, RELEUKO, ZARXIO

FULPHILA, ZIEXTENZO

Granulocyte Colony Stimulating Factors

NIVESTYM

Hematopoietic & Thrombopoietic Agents

APHEXDA

plerixafor

For Hemophilia A with inhibitors: ALHEMO, HEMLIBRA

For Hemophilia A without inhibitors: ALHEMO, HEMLIBRA, HYMPAVZI For Hemophilia B with inhibitors: ALHEMO For Hemophilia B without inhibitors: ALHEMO, HYMPAVZI

Hemophilia Agents

QFITLIA

Hemophilia Gene Therapy Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors Iron Replacement Agents Sickle Cell Disease Agents

BEQVEZ

HEMGENIX

VAFSEO

PROCRIT, RETACRIT

MONOFERRIC SIKLOS, XROMI

sodium ferric gluconate complex, VENOFER

hydroxyurea, DROXIA eltrombopag, NPLATE

ALVAIZ

Thrombocytopenia Agents

MULPLETA

DOPTELET

Coverage may be approved for the treatment of Myelodysplastic Syndrome with Transfusion- Dependent Anemia under certain conditions.

Miscellaneous Hematology Agents RYTELO

HEPATITIS Hepatitis C

LEDIPASVIR/SOFOSBUVIR, MAVYRET, SOFOSBUVIR/VELPATASVIR, SOVALDI

EPCLUSA, HARVONI, VOSEVI, ZEPATIER

atazanavir, darunavir, fosamprenavir, lopinavir/ritonavir, ritonavir, PREZISTA

PREZCOBIX

HIV Antiretrovirals

Coverage may be approved for the treatment of human immunodeficiency virus-1 infection in heavily treatment-experienced patients with multidrug-resistant infection.

Note: Current patients established on therapy are allowed to continue therapy.

RUKOBIA ER

STRIBILD

BIKTARVY, GENVOYA

MUSCULOSKELETAL & RHEUMATOLOGY Muscle Relaxants & Antispasmodic Agents

METHOCARBAMOL 1,000MG TABLETS

methocarbamol 500mg tablets

(continued)

© 2025 Evernorth Health Services. All rights reserved. All trademarks are the property of their respective owners.

CRP1386903A 204612 EXCL-NPF-26 (08/08/2025)

Page 12

Made with FlippingBook. PDF to flipbook with ease