ESTRO 2026 - Abstract Book PART II

S2362

Physics - Quality assurance and auditing

ESTRO 2026

1 Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark. 2 Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. 3 Department of Medical Physics, Aarhus University Hospital, Aarhus, Denmark. 4 Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. 5 Department of Medical Physics, Aalborg University Hospital, Aalborg, Denmark. 6 Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark. 7 Laboratory of Radiation Physics, Odense University Hospital, Odense, Denmark. 8 Department of Medical Physics, University Hospital of Southern Denmark, Vejle, Denmark. 9 Department of Oncology, Zeeland University Hospital, Næstved, Denmark. 10 Department of Radiotherapy, Stavanger University Hospital, Stavanger, Norway. 11 Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden. 12 Department of Clinical Medicine, The Arctic University of Norway, Tromsø, Norway. 13 Department of Medical Physics, Oslo University Hospital, Oslo, Norway. 14 Department of Radiation Oncology, Uppsala University Hospital, Uppsala, Sweden. 15 Department of Diagnostics and treatments, Sahlgrenska Cropehensive Cancer Centre, Gothenburg, Sweden. 16 Department of Radiotherapy, Nordland Hospital Trust, Bodø, Norway. 17 Radiation Oncology Department, National Oncology Institute of Slovakia, Bratislava, Slovakia. 18 Department of Oncology and Medical Physics, Haukeland University Hospital, Bergen, Norway. 19 Department of Radiotherapy, Clinic of Oncology, Ålesund Hospital, Aalesund, Norway. 20 Department of Medical Physics and Radiotherapy, UC Christus Cancer Center, Santiago, Chile. 21 Department of Oncology, Sørlandet Hospital, Kristiansand, Norway Purpose/Objective: Partial breast irradiation (PBI) has become standard for selected low-risk breast cancer patients, aiming to reduce late effects while maintaining local control1,2. The DBCG RT Natural trial (NCT03646955) investigated whether PBI could be safely omitted in selected low- risk breast cancer patients. The primary aim of this study is to report treatment planning quality assurance for patients receiving PBI by evaluating dose distributions in targets and organs of interest within protocol-defined planning objectives. Material/Methods: Women aged ≥ 60 years with unilateral, unifocal, node- negative invasive breast cancer ≤ 20 mm, grade I–II, ER- positive, and HER2-negative were eligible. Patients were randomised 1:1 to PBI (40 Gy/15 fractions) versus no radiotherapy. The PBI clinical target volume (CTVp_PBI), delineated as the tumour bed plus 15 mm, was to receive ≥ 95% of the prescribed dose (V95%),

Conclusion: The 6DOF couch on Halcyon V5 had overall mechanical correction accuracies ≤ 0.1cm. The integration of the 6DOF couch with SGRT increases usability and efficiency of multi-isocenter treatments by allowing for accurate rotational corrections and patient-centric translations-under-rotation. References: Schmidhalter D, Fix MK, Wyss M, et al. Evaluation of a new six degrees of freedom couch for radiation therapy. Med Phys 2013;40(11):111710. DOI: 10.1118/1.4823789. Keywords: 6DOF, O-ring, rotation Digital Poster Highlight 2427 Quality Assurance in the Danish Breast Cancer Group (DBCG) RT Natural Trial Kristine W Høgsbjerg 1,2 , Mette S Thomsen 3 , Kristian Boye 4 , Ingelise Jensen 5 , Susanne N Bekke 6 , Ebbe L Lorenzen 7 , Henrik D Nissen 8 , Abhilasha Mikalsen 9 , Kjell I Dybvik 10 , Elinore Wieslander 11 , Veronika Tømmerås 12 , Stine G Mikalsen 13 , Ulf Isacson 14 , Camilla Grahn 15 , Kristine Perander 16 , Miroslava Dobrnova 17 , Britt Nygaard 18 , Ida M Holmeset 19 , Rodrigo E F Manriquez 20 , Kari P Buhaug 21 , Birgitte V Offersen 1,2

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