S2442
Physics - Radiomics, functional and biological imaging, and outcome prediction
ESTRO 2026
Poster Discussion 2563 An interpretable multimodal radiopathomics model predicting pCR to neoadjuvant chemoimmunotherapy in esophageal squamous cell carcinoma. Zhen Zhang 1,2 , Baojia Qi 1 , Andre Dekker 2 , Leonard Wee 2 , Yongling Ji 1 1 Raditation Oncology, Zhejiang Cancer Hospital, Hangzhou, China. 2 Department of Radiation Oncology (Maastro), Maastricht University Medical Centre+, Maastricht, Netherlands
Conclusion: Our multicenter prediction model identified radiation dose to the pulmonary veins and left atrium (PC1), along with multiple treatment and patient factors, as key predictors of AF. Given the dosimetric effect and the model’s good calibration, it may help optimize radiotherapy treatment planning and technique selection with the potential to reduce the risk of AF. References: [1] Miller, E. D., Wu, T., McKinley, G., et al. (2024). Incident Atrial Fibrillation and Survival Outcomes in Esophageal Cancer following Radiotherapy. International journal of radiation oncology, biology, physics, 118(1), 124– 136. https://doi.org/10.1016/j.ijrobp.2023.08.011 Keywords: NTCP-model, Atrial fibrillation, Esophageal cancer
Digital Poster 2633
Associations of late toxicity after head and neck radiotherapy based on OAR doses and clinical characteristics Vera-Maria Enckell 1,2 , Pihla Ranta 3 , Sami Suilamo 1,2 , Harri Merisaari 4,5 , Iiro Ranta 6 , Manish Kakar 7 , Heikki Irjala 3 , Heikki Minn 1 , Eirik Malinen 8,9 1 Department of Oncology and Radiotherapy, Turku University Hospital, Turku, Finland. 2 Department of Medical Physics, Turku University Hospital, Turku, Finland. 3 Department of Otorhinolaryngology – Head and Neck Surgery, Turku University and Turku University Hospital, Turku, Finland. 4 Turku Brain and
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