ESTRO 2026 - Abstract Book PART I

S1357

Interdisciplinary - Global health

ESTRO 2026

References: Detecção Precoce Do Câncer / Instituto Nacional de Câncer José Alencar Gomes Da Silva.Corrêa, F. M., Migowski, A., de Almeida, L. M. & Soares, M. A. Cervical cancer screening, treatment and prophylaxis in Brazil: Current and future perspectives for cervical cancer elimination. Front. Med. (Lausanne)9, 945621 (2022).Health Policy Title: Cracking the Code: Pioneering Early Detection and Management of Breast Cancer in the Brazilian Public Healt.Toledo, C. M., Almeida, L. M. P. R. de, Averbach, M. & Barbosa, J. de L. E. S. Analysis of the tracking initiatives of colorectal cancer in Brazil. Arq. Gastroenterol.60, 450–462 (2023).Estatísticas de câncer. Instituto Nacional de Câncer - INCAhttps://www.gov.br/inca/pt- br/assuntos/cancer/numero Keywords: Inequality, Health Access, Screening Self-Perceived Health Among Prostate Cancer Patients: The Paradox of Age and Marital Status. Fatjona Kraja 1,2 , Aurel Janko 1,3 , Rezart Xhani 1,3 , Gezim Galiqi 4 1 Surgery, Faculty of Medicine, University of Medicine, Tirana, Albania. 2 Oncology, UHC Mother Teresa, Tirana, Albania. 3 Urology, UHC Mother Teresa, Tirana, Albania. 4 Urology, Shkodra regional Hospital, Shkodra, Albania Purpose/Objective: This study aimed to comprehensively evaluate self- perceived health (SPH) among prostate cancer patients and to identify the sociodemographic and clinical determinants associated with poorer SPH outcomes. We aimed to explore how factors such as age, marital status, treatment modality, time since Digital Poster 1767 diagnosis, and disease stage influence patients’ perceptions of their overall health and well-being following cancer diagnosis and treatment. Material/Methods: A cross-sectional study was conducted on 200 prostate cancer patients attending follow-up at at the university oncology clinic. Patients completed a validated self- perceived health questionnaire alongside sociodemographic and clinical data. SPH was rated on a five-point scale (very good, good, average, poor, very poor) and subsequently dichotomized into two categories: “not poor” (very good/good/average) and “poor health.” Demographic and disease-related variables were analyzed, and logistic regression was performed to identify factors independently associated with poor SPH. Results: Patients mean age was 68 (range 58–83). Among the study population, 37% of patients received adjuvant or

salvage radiotherapy following radical prostatectomy, while 63% underwent definitive treatment, with hypofractionated radiotherapy. Overall, 48% of the patients reported poor SPH during followup. Interestingly, younger patients (<65 years) reported significantly poorer SPH compared to older patinets (p=0.02), reflecting a stronger psychosocial impact of cancer diagnosis and treatment on perceived vitality and masculinity. Moreover, prostate cancer patients post radical prostatectomy reported poorer SPH compared with the patients treated with radical radiotherapy(p=0.03). In addition, married men were more likely to report poor SPH compared to unmarried or widowed men (p=0.04), suggesting that relational dynamics and caregiving expectations contribute to a more negative SPH among married prostate cancer patients. When analyzing SPH in relation to time since diagnosis, patients more than two years post-diagnosis reported significantly better SPH (p = 0.04), suggesting progressive psychological adaptation and functional recovery over time. Clinical stage and treatment type were not significantly associated with SPH. Conclusion: Younger and married prostate cancer patients reported worse self-perceived health, highlightingthe need for age and psychosocial interventions. Incorporating SPH assessment into routine follow-up could help identify vulnerable subgroups and identify supportive care needs to improve quality of life in prostate cancer patients. Keywords: Prostate cancer, SPH, psychosocial factors Financial toxicity as an independent predictor of quality of life in gastric cancer patients: A cross- sectional study. Fatjona Kraja 1,2 , Bledar Kraja 3,4 , Erald Karaulli 2 , Enes Hafizi 2 , Arben Beqiri 1,5 1 Surgery, Faculty of Medicine, University of Medicine, Tirana, Albania. 2 Oncology, UHC Mother Teresa, Tirana, Albania. 3 Biomedical and Experimental Sciences, Faculty of Medicine, University of Medicine, Tirana, Albania. 4 Gastroenterology and Hepatology, UHC Mother Teresa, Tirana, Albania. 5 Surgery, UHC Mother Teresa, Tirana, Albania Purpose/Objective: This study aimed to evaluate the impact of financial toxicity on patients with gastric cancer based on validated assessment instrument, with the objective of determining whether financial toxicity serves as an independent predictor of overall quality of life in gastric cancer patients, beyond the influence of clinical and demographic factors. Digital Poster 1771

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