S1451
Interdisciplinary - Other
ESTRO 2026
acquisition, registration of the CBCT with diagnostic CT, physician contour approval, structures and plan transferred to the CBCT, plan approval by the physicist, and a final CBCT for positional verification and treatment delivery. Results: The retrospective analysis demonstrated high dosimetric equivalence between the conventional and CBCT-based plans.For all the 25 patients, the agreement between the CT and CBCT plans, measured using the V95% covered by D95% for both the CTV and PTV, was consistently within 1-2%Measured dose distributions using the SunNuclear ArcCheck demonstrated that both the CT Sim and CBCT plans passed the gamma analysis criterion of 2mm/2%. Conclusion: HyperSight CBCT can be safely utilized to plan palliative treatments with static fields without compromising the integrity of the treatment plan or the delivered dose. This Sim-less workflow allows completion of patient simulation and treatment in the same session, significantly shortening the patient's overall stay in the radiation department, thereby increasing patient satisfaction. References: 1. Evaluation of the dosimetric accuracy of HyperSight CBCT for CBCT-only adaptive radiotherapy workflow , Phys Med 2025, Sep; Francesca Dusi; Fabio Busato; Alessandro Testolin; Davide Fiorentin ; Francesca Tessari; Matti Nicoletto, Marco Fusella2. Feasibility of HyperSight CBCT for adaptive radiation therapy: A phantom benchmark study of dose calculation accuracy and delivery verification on the Halcyon; J Appl Clin Med Phys, 2025 Sep9; 26(9) Nicholas Nelson; Courtney Oare; Geoff Nelson; Thomas Martin; Jessica Huang; Hui Zhao3. Dosimetric feasibility of cone-beam CT-based treatment planning compared to CT-based treatment planning , Intr Journal of Rad Oncology Biology Physics; 66(5) 1553-61 ; Sua Yoo; Fang Fang Yin Keywords: simless, palliative treatments, HyperSight Multidisciplinary Tumor Boards Significantly Alter Radiotherapy Treatment decisions and Improve Guidance Adherence in a Resource-Limited setting Aditi Paul Chowdhury 1 , Nowshin Taslima Hossain 1 , Nusrat Ahmed 2 , Sura Jukrup Momtahena 1 , Rubama Karim 1 , Jannatul Ferdause 1 , M Saiful Haq 3 1 Radiation oncology, Ahsania Mission Cancer and General Hospital, Dhaka, Bangladesh. 2 Cancer registry, Ahsania Mission Cancer and General Hospital, Dhaka, Bangladesh. 3 Radiation oncology, UPMC Hillman Cancer Center, Pittsburg, USA Digital Poster Highlight 3683
MDT are integral to modern oncology, optimizing limited resources in low- and middle-income countries (LMICs). While MDTs improve outcomes in a high- income setting, robust evidence in LMICs remain sparse. Consistent delivery of evidence-based radiotherapy (RT) is challenging in low- and middle- income countries (LMICs) due to lack of proper diagnosis, staging errors, and limited radiation treatment facility. This retrospective study evaluates the real-world impact of MDTs on treatment decision- making, guideline adherence, and clinician satisfaction in a resource-constrained radiotherapy center. Material/Methods: Methods: This was a retrospective cohort study conducted at Ahsania Mission Cancer and General Hospital, Dhaka, Bangladesh, from January 2023 to June 2025. All patients (n=370) discussed in MDTs were included. Data collected: demographics, cancer type, pre/post-MDT treatment plans, RT indication/omission, sequencing of multimodality therapy, and guideline adherence. Treatment changes were classified as major (modality switch, RT addition/omission, surgery or systemic therapy change) or minor (RT dose/fractionation/sequence adjustments. Adherence to NCCN/ESMO guidelines was assessed pre- and post MDT. Results: Result : MDT review modified treatment in 64% of cases, including 28% major and 36% minor changes. RT-specific modifications accounted for a substantial proportion, especially in breast, lung, and head-and- neck cancers. MDTs corrected staging discrepancies, reduced inappropriate RT omission, and optimized chemo-RT sequencing. Guideline adherence increased from 52% pre-MDT to 89% post-MDT (p < 0.001). Clinician satisfaction with MDT-derived RT recommendations was high (4.6/5), and adherence to MDT decisions reached 91% despite resource limitations. Conclusion: Conclusion : Despite resource constraints, MDTs significantly improve treatment decision-making and guideline adherence in LMIC settings. This study provides actionable evidence for integrating MDTs as a core component of cancer care in low-resource environments. References: References: 1. Prasad V, et al. Multidisciplinary cancer care: A systematic review of outcomes in oncology. Lancet Oncology. 2021;22(12):e542–e553.2. Gooiker GA, et al. Impact of multidisciplinary tumor boards on treatment planning and outcomes in cancer care. Ann Surg Oncol. 2013;20(11):3493–3501.3. Soukup T, et al. The role and effectiveness of multidisciplinary team meetings in oncology: A systematic review of the literature. Cancer Treat Rev. 2018;63:1–13.4. Keating NL, et al. Tumor boards and adherence to evidence-
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