S1505
Interdisciplinary - Quality assurance and risk management
ESTRO 2026
Manchester, United Kingdom. 20 National Radiotherapy Trials Quality Assurance (RTTQA) Group, Mount Vernon Cancer Centre, Northwood Middlesex, United Kingdom. 21 Radiation Oncology, Irish Research in Radiation Oncology Group, Dublin, Ireland Purpose/Objective: The Irish Radiation Research Oncology Group (IRROG) promotes equitable access to radiotherapy clinical trials across all radiotherapy centres in Ireland. To strengthen collaboration between trial sites, a national Radiotherapy Quality Assurance (RTQA) programme is being developed, coordinated by IRROG.The IRROG project aim was to develop a collaborative Irish RTQA working group (I-RTQA-WG) to foster national and international collaboration, align RTQA processes with international standards, and support clinical trial readiness through shared learning, peer review, and benchmarking. Material/Methods: The I-RTQA-WG comprising medical physicists, radiation therapists, dosimetrists and radiation oncologists was established, with representatives from six Irish centres (Figure 1) preparing to open the UK NIHR-funded and ICR-sponsored FAST-Forward Boost trial (NIHR157800) with independent RTQA through the UK Radiotherapy Trials QA (RTTQA) GroupI-RTQA- WG collaborated in developing planning and Image Guided Radiotherapy (IGRT) techniques necessary to deliver simultaneous integrated boost (SIB) radiotherapy regimens required for the trial, aiming to reduce trial start-up time across all sites through collaboration and information sharing.The standard- of-care arm consists of a simultaneous integrated boost of 48 Gy in 15 fractions. At the start of the project, this fractionation and technique were routinely used at only three participating Irish radiotherapy sites for non-nodal cases, and at just one site for nodal cases. Consequently, centres required comprehensive training and credentialing to ensure they could plan and deliver both standard-of-care and intervention regimens, enabling participation in this important clinical trial.
Results: Regular virtual meetings of the I-RTQA WG facilitated streamlined communication with the UK RTTQA Group, reducing the duplication of queries, and enabling shared learning. Credentialing experiences, treatment planning techniques, and imaging guidance strategies were exchanged among sites (Figure 2). Centralised feedback from RTTQA was openly shared between I-RTQA-WG sites, fostering a culture of peer learning and continuous service improvement.The I- RTQA-WG served as a centralised hub for information exchange, allowing timely resolution of site-specific challenges and direct engagement with the UK RTTQA team via structured Q&A sessions.
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