S711
Clinical – Lower GI
ESTRO 2026
Proffered Paper 2390
Dosimetry results from a global randomized trial of iodinated perirectal spacing in prostate cancer patients treated with SBRT (NCT04905069) Pierre Blanchard 1 , Sean Collins 2 , Jenny Nobes 3 , Nachiappan Palaniappan 4 , Nicola Simoni 5 , Alfonso Gomez-Iturriaga 6 , Peter Sankey 7 , Jarad Martin 8 , Paul J Kelly 9 , Krisha J Howell 10 , Christos Mikropoulos 11 , Vincent Khoo 12 , Glen Gejerman 13 , Amit Bahl 14 , Alain Toledano 15 , Aurel Messas 16 , Jeremy Croker 17 , Tanya Holt 18 , Felipe Couñago 19 , Jens Lustenberger 20 , Asunción Hervás Morón 21 , Danielle Vannan 22 , Erin L Chaussee 22 , Michael Zelefsky 23 , Suneil Jain 24 1 Radiation Oncology, Institut Gustave Roussy, Villejuif, France. 2 Radiation Oncology, USF Health Morsani College of Medicine, Tampa, USA. 3 Oncology, Norfolk and Norwich University Hospital NHS Trust, Norwich, United Kingdom. 4 Clinical Oncology, Velindre Cancer Centre, Whitchurch, United Kingdom. 5 Radiation Oncology, University Hospital of Parma, Parma, Italy. 6 Radiation Oncology, Cruces University Hospital, Biobizkaia Health Research Institute, University of the Basque Country (UPV/EHU), Barakaldo, Spain. 7 Uro- Oncology, Derriford Hospital, University Hospitals, Plymouth, United Kingdom. 8 Radiation Oncology, Calvary Mater Newcastle, Waratah, Australia. 9 Radiation Oncology, Bon Secours Radiotherapy Cork/UPMC Hillman Cancer Centre, Cork, Ireland. 10 Radiation Oncology, Michigan Healthcare Professionals, Farmington Hills, USA. 11 Clinical Oncology, St. Luke's Cancer Centre, Guildford, United Kingdom. 12 Clinical Oncology, Royal Marsden Hospital, London, United Kingdom. 13 Radiation Oncology, New Jersey Urology, Clifton, USA. 14 Clinical Oncology, Bristol Haematology and Oncology Centre, Bristol, United Kingdom. 15 Radiation Oncology, Institut De Radiotherapie et De Radiochirurgie Hartmann, Levallois-Perret, France. 16 Urological Surgery, American Hospital of Paris, Paris, France. 17 Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, Australia. 18 Radiation Oncology, Princess Alexandra Hospital, Woolloongabba, Australia. 19 Department of Radiation Oncology, GenesisCare, Hospital Universitario San Francisco de Asís and Hospital Universitario La Milagrosa, Madrid. European University of Madrid, Madrid, Spain. 20 Radiotherapy, University Hospital Basel, Basel, Switzerland. 21 Radiation Oncology, Hospital Universitario Ramon y Cajal, Madrid, Spain. 22 Urology, Boston Scientific Corporation, Marlborough, USA. 23 Radiation Oncology, NYU Medical Center, New York, USA. 24 Radiation Oncology, Queen's University Belfast, Belfast, United Kingdom Purpose/Objective: Prostate stereotactic body radiotherapy (SBRT) is a standard treatment for intermediate risk prostate
Conclusion: The SEOR-GI national survey highlights a rapid and homogeneous integration of TNT and organ- preserving strategies across Spain. Advanced image- guided techniques and multidisciplinary decision- making are widespread, reflecting strong alignment with international guidelines and providing a framework for future collaborative research. References: Wo JY, Ashman JB, Bhadkamkar NA, Bradfield L, Chang DT, Hanna N, Hawkins M, Holtz M, Kim E, Kelly P, Ling DC, Olsen JR, Palta M, Raldow AC, Ruiz-Garcia E, Sheybani A, Stitzenberg KB, Das P. Radiation Therapy for Rectal Cancer: An ASTRO Clinical Practice Guideline Focused Update. Pract Radiat Oncol. 2025 Mar- Apr;15(2):124-143. doi: 10.1016/j.prro.2024.11.003. Epub 2024 Nov 25. PMID: 39603501. Keywords: Rectal cancer, Total neoadjuvant therapy
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