S76 D).
Brachytherapy - Gynaecology
ESTRO 2026
study. Lancet Oncol. 2021 Apr;22(4):538-547.2. Pötter R, Haie-Meder C, Van Limbergen E, et al. Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol. 2006 Jan;78(1):67- 77. 3. https://www.embracestudy.dk/UserUpload/Publi cDocuments/EMBRACE%20II%20Protocol.pdf Comparative cost-benefit of electronic versus HDR iridium-192 brachytherapy for exclusive vaginal cuff treatment in postoperative endometrial cancer Sergio Lozares 1 , Víctor González 2 1 Physics and Radiation Protection, Miguel Servet University Hospital, Zaragoza, Spain. 2 Physics and Radiation Protection, IVO Foundation, Valencia, Spain Purpose/Objective: To compare economic and dosimetric outcomes between electronic brachytherapy (eBT) and high- dose-rate iridium-192 ( ¹⁹² Ir HDR) for exclusive vaginal cuff treatment in postoperative endometrial cancer, under equivalent clinical conditions. Material/Methods: A retrospective analysis was conducted in two Spanish centers between 2019 and 2023, including 185 patients: 115 treated with eBT (Xoft Axxent, 50 kVp) and 70 with ¹⁹² Ir HDR (Oncentra Brachy). All patients received 3 × 7 Gy prescribed at 5 mm from the applicator surface. Dosimetric parameters (D ₉₀ , V ₁₅₀ , V ₂₀₀ for CTV; D ₂ cc, D ₁ cc, D ₀ . ₁ cc for bladder, rectum, and sigmoid) were compared. Cost analysis was performed from the hospital perspective, considering equipment depreciation, source replacement, and maintenance. Personnel and procedural costs were assumed identical. Results: Digital Poster 3820
Conclusion: Institutional experience in MR-IGABT reflect a decade of evolution in radiotherapy standards and brachytherapy planning quality to achieve excellent clinical outcomes in Chinese patients. Keywords: MR-guided adaptive brachytherapy, cervical cancer References: 1. Pötter R, Tanderup K, Schmid MP, et al. MRI-guided adaptive brachytherapy in locally advanced cervical cancer (EMBRACE-I): a multicentre prospective cohort
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