Riley Children's Health Annual Report 2022 – 2023

The pediatric nephrologists at Riley Children’s Health are leaders in using novel technologies and research breakthroughs to launch new clinical programs that lead to better treatments for children impacted by kidney disease. Our nephrology specialists provide comprehensive evaluation and treatment for children with kidney disease or kidney failure. NEPHROLOGY


■ 26 active clinical studies; eight funded by the National Institutes of Health ■ Member of the Pediatric Nephrology Research Consortium , participating in the international CureGN (with high enrollment and retention) and HIKO STEC studies ■ Long-standing participant in the Chronic Kidney Disease in Children (CKiD) and North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) studies ■ Recently participated in the industry- sponsored study, Hemoglobin Maintenance in Pediatric ESRD Patients by Ferric Pyrophosphate Citrate (FPC)

Riley Nephrology had a higher aquapheresis volume than any other pediatric program in the nation for the fourth quarter of 2022.

DIVISION CHIEF David S. Hains, MD, MBA Byron P. & Francis D. Hollett Professor of Pediatrics, IU School of Medicine > Connect with Dr. Hains on Doximity. >

Program distinctions

■ Nationally ranked among the top 15 pediatric nephrology programs by U.S. News & World Report

49 research publications in 2022

10 board certified physicians


■ 12th pediatric center in the nation to launch aquapheresis, allowing for continuous renal replacement therapy in smaller patients, including neonates ■ Offers ambulatory blood pressure monitoring for patients with asymptomatic elevated blood pressure; completes more than 500 24-hour ambulatory blood pressure monitor readings annually ■ Home to a comprehensive multidisciplinary pediatric kidney transplant program incorporating pediatrics and internal medicine, nephrology, adolescent medicine, and psychology

See full team member list

Ambulatory Blood Pressure Monitoring Program: 2017 – 2022 *






Proceedings of the National Academy of Sciences (PNAS): September 2022 Human Neutrophil Peptides 1-3 Protect the Murine Urinary Tract from Uropathogenic Escherichia Coli Challenge JAMA Network Open: September 2022 Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children: A Modified Delphi Consensus Statement Journal of Cellular Biochemistry: August 2022 MAP3K7 Is an Innate Immune Regulatory Gene with Increased Expression in Human and Murine Kidney Intercalated Cells Following Uropathogenic Escherichia Coli Exposure Scientific Reports: January 2022 Female and Male Mice Have Differential Longterm Cardiorenal Outcomes Following a Matched Degree of Ischemia-Reperfusion Acute Kidney Injury









Specialized programs

* Number of studies performed by Riley Nephrology

Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Program Patients are seen by specialists from nephrology, urology, and medical and molecular genetics during a single visit that occurs monthly. Neonatal Acute Kidney Injury (AKI) Program A collaboration with Riley Neonatology, this program has established standardized care guidelines to improve recognition and management of neonates with AKI. Our neonatal AKI surveillance and consultation program—one of the few in the nation—captures all neonates with an AKI episode and creates streamlined outpatient follow-up and research study enrollment.

Pediatric Kidney Transplant Program ■ Riley Children’s ranks within the first quartile nationally in pediatric kidney transplant volume and is among the top centers in patient outcomes. ■ We are a longtime member of the Improving Renal Outcomes Collaborative , which brings together top-tier pediatric kidney transplant programs to improve health outcomes and quality of life for children with kidney transplants.

24-Hour Ambulatory Blood Pressure Monitoring Program and APBM First Patients with elevated blood pressure readings and/or their providers have access to a rapid visit involving a 24-hour ambulatory blood pressure monitor before a full clinic consultation. Stone Program Focusing on long-term kidney stone prevention and relief, this program educates patients on the importance of making meaningful diet and fluid intake changes to help prevent and control symptoms. Young Adult Transition Program This program, designed for 18- to 25-year-old patients with chronic kidney disease, focuses on this population’s specific needs with the goal of ensuring a smooth transition to adult healthcare providers.

Riley Children’s has the only pediatric dialysis unit in Indiana. We provide inpatient (including NICU and PICU) and acute hemodialysis and peritoneal dialysis services.

■ Related research: Projects describing the immune response to vaccinations and analyzing the results of a new Pediatric Kidney Transplant Transition Program at Riley Children’s ■ Quality improvement initiatives: Improving medication adherence, reducing length of stay and readmissions

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Annual Report 2022 – 2023


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