Cardiovascular patient analysis and planning by Materialise
3D Planning from Bench to Bedside
Cardiovascular patient analysis and planning by Materialise
The recipe for success
Achieve your goal of helping patients by bringing life-changing technology to market.
Be competitive Gain market share and stay ahead with innovative solutions for clinicians and patients Be efficient Realize cost benefit as a result of robust and scalable processes to reach and help more patients
Trends that dictate the pace The race to market Successfully bring a new generation of C&V devices to market as rapidly as possible to bring transformative solutions for clinicians and patients. In being the first, you’ll capture the largest market share and maximize the impact of your technology on cardiovascular healthcare. Your research will impact patient lives and you’ll gain return on your investments. Fast design adaptations and optimal patient inclusion rates are essential to assure efficiency in R&D and clinical trials. This efficiency combined with good clinical outcomes will help increase your chances in winning the race.
Personalized guidance to navigate complex treatments
Society is becoming more demanding as technology has evolved to enable tailored experiences in all aspects of life. Clinicians are no exception — they need clear and efficient communication tools for planning at their fingertips. They want a highly personalized service that gives them critical information where and when they need it. With an intuitive service that bypasses tedious processes, clinicians won’t need to look further.
Face the challenges Overcome your challenges and successfully bring transformative solutions to clinicians and patients. Current innovation in 3D planning and online planning communication can give you a competitive edge and expand your reach in helping more patients. With the latest tools in hand, your new process efficiencies will assist you in the race to the market.
The power of 3D planning
Bring clarity to complexity by using 3D CT planning. Deliver 3D printing definition to the virtual world and efficiently handle increasing number of cases without compromising your insights.
Gain market share and be the first on the market Create evidence with reliable tools for post-op analysis Ensure favorable clinical outcomes through planning
Optimize patient selection
Optimally prepare physicians for procedures Provide a clear road map for a successful intervention
Measure accurately and gain better insights on anatomy Contribute to treating more patients and accelerating clinical trials
Boost their confidence
The power of online planning
Communicate clearly with clinicians and your colleagues by digitizing and personalizing the service provided. Deliver added value that clinicians didn’t even know they needed while cementing their loyalty with ease of use.
Facilitate communication Involve all stakeholders easily Anywhere, anytime
Gain efficiency Save time by avoiding tedious processes Manage your cases while scaling up
FROM BENCH...
...TO BEDSIDE
R&D
CLINICAL TRIALS
AFTER MARKET CLEARANCE
3D every step of the way Benefit from using 3D throughout the product life cycle.
in R&D
in clinical trials
after market clearance
Correctly quantify your target population and validate your prototype in a realistic test set-up. Learn more >
Maximize your success with accurate patient screening and planning, based on true 3D.
Scale up the number of patients while remaining consistent and efficient.
Learn more >
Learn more >
After market clearance challenges
Once your product is commercially available, there are still challenges remaining to stay competitive and efficient.
Making it intuitive for physicians to adopt your novel structural heart device Handling increasing patient numbers in a consistent and time-efficient way Facilitating effective communication and case management Collecting evidence and prioritizing good outcomes for patients
How Materialise can support after market clearance
“Cat-scan imaging of the chest, in conjunction with Mimics, helped to determine whether the SynCardia Total Artificial Heart could actually be placed in the child’s chest.”
Innovative solutions can support you in extending a personalized experience to clinicians.
Delivering detailed 3D insights on how the implanted device and the patient’s anatomy would interact Automating your 3D planning workflow to reduce time and inter-user variability Providing an online case review and communication platform
-D. Bradford Sanders, chief perfusionist at Phoenix Children’s Hospital
Offering reliable tools for 3D post-op analysis
Clinical trial challenges
Once your product reaches the trial phase, innovative advantages will help power you through the race to market:
Selecting the most suitable patients while balancing the avoidance of cases with assured poor outcomes and cases where a suitable patient is excluded Ensure there are no surprises in the CATHLab and that the physicians are well trained and prepared Obtaining favourable clinical outcomes while ensuring data integrity, to accelerate market clearance. Manage the increasing number of cases from feasibility to pivotal trials efficiently
How Materialise can support in clinical trials
Access a customized toolbox to efficiently deal with every challenge that arises.
Ensuring accurate tools for patient screening
Providing consistent patient planning software and training models
Assuring medically cleared tools
Automating your 3D planning workflow to support your scale-up
“Time is of critical importance for a small company. We need to be efficient in what we do, and we need to do it in a timely manner because time is equal to money. There is a limited amount of funds and it is up to us to show that our technology works, and that it works consistently for us to be successful. This is where the relationship with Materialise and using the right tools to help us succeed play a huge role” - Saravana Kumar, PhD, Vice President of R&D and Operations, 4C Medical Technologies, Minneapolis, USA
Bringing a mitral regurgitation solution to the market
4C Medical Technologies is a medical device company working on minimally invasive solutions for structural heart diseases. The team worked with Materialise Mimics Innovation Suite (MIS) to bring to market their award-winning AltaValve, an innovative solution to address mitral valve regurgitation. These are the four main phases that Materialise MIS was able to support in according to the team:
Gathering relevant design input to develop their product
Liaising with regulatory bodies
Completing clinical trials with consistent 3D planning
Designing tools to train clinicians in device use
Read the full case here.
R&D challenges When in the R&D phase, there are multiple hurdles to overcome in assessing and identifying a potential device.
Understanding complex anatomy and pathology in 3D
Having relevant design input by quantifying the target population anatomy Verifying the device during pre-clinical tests and continuing to animal and human tri- als with more confidence in your design
“For our study, it was important to carry out qualitative and quantitative comparisons between 3D models and the Mimics Innovation Suite allowed us to do just that. Furthermore, it was easy to import our CT data and perform segmentations in order to generate accurate 3D models and meshes. The results were easily exported into other applications for further testing, such as CFD.” - Bert Vandeghinste, PhD, Ghent University, Belgium
How Materialise can support in R&D
Quickly iterate and determine the best results with the correct tools in-hand.
Providing software and services to efficiently create accurate 3D models Providing accurate software and services to visualize and measure complex anatomy on a substantial number of virtual patients
Generating realistic in vitro and in silico test set-ups
Innovative Methods for Aortic Aneurysm Device Testing
Medtronic is the global leader in medical technology with an endovascular division that designs and manufactures devices to treat cardiovascular disease such as thoracic aortic aneurysms.
They use Mimics Innovation Suite to:
Perform segmentation, centerline calculations, and measurements to collect relevant design input
Quantify device performance through a realistic 3D-printed benchtop model
Read the full case here.
FROM BENCH...
...TO BEDSIDE
R&D
CLINICAL TRIALS
AFTER MARKET CLEARANCE
Materialise software Mimics Medical 3-matic Medical
R&D
Clinical Trials
After Market Clearance
Mimics Viewer Mimics Enlight SurgiCase Materialise service Engineering & 3D Printing services ADaM services HeartPrint services Custom Plugin Development Training and consultancy
Primary use
Secondary use
Our Portfolio
Software
Services
Materialise Mimics Medical Market-leading medical segmentation software that converts medical images into accurate virtual 3D models. Materialise 3-matic Medical Design optimization software that supports in designing personalized models and carry out advanced analyses. Materialise Mimics Enlight Clinical 3D planner based on Materialise Mimics technology. Materialise Mimics Viewer Online platform that enables effective planning between clinical teams using Mimics and Enlight. Materialise SurgiCase Online case management platform that provides communication for personalized devices, and the ability to plan with increased volumes of patients.
Materialise ADaM services Population analysis that finds and verifies optimal medical device designs through anatomical data mining (ADaM) services. Materialise HeartPrint services Realistic 3D-printed heart modelsto provide better insight into complex pathologies and to accelerate R&D and clinician training. Materialise Engineering & 3D Printing services 3D analysis and printing for a limited number of medical images. Materialise Custom Plugin Development Customized development to integrate your workflow within the Materialise Mimics and Mimics Enlight software.
Availability of the products may differ from region. Materialise Mimics, 3-matic and Mimics Enlight research are available in all regions. Note that these are not medical devices.
Proven track record
patents granted/ pend ing
years of Materialise
+30
370+
+2100 employees
patients helped yearly
50K+
scans analyzed with medical software
+5M
The recipe for success This is how you can achieve your goal of helping clinicians and patients by bringing life-changing technology to market.
Be competitive Gain market share and stay ahead with innovative solutions for clinicians and patients Bring clarity to complexity with accurate measurements and better insights on anatomy using the power of 3D planning.
Personalize your service and optimally prepare your physicians with online planning.
Be efficient Realize cost benefit as a result of robust and scalable processes to reach and help more patients
Digitize your planning and centralize your case management with the power of online planning.
Save time in your pre-procedural planning by avoiding tedious processes with the power of 3D planning.
Creating a better and healthier world materialise.com/medical
©2021 Materialise NV. All rights reserved - Materialise and the Materialise logo are trademarks of Materialise in the EU, US and/or other coun- tries. L-101618-01 This information is intended for healthcare professionals only.
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