RNSH DIVISION OF SURGERY & ANAESTHESIA
RESEARCH ACTIVITY REPORT 2023 - 2024
AUTHOR: RNSH SERT INSTITUTE
Acknowledgements: A special thanks to all surgeons across RNSH departments who generously provided information and feedback during the development of this document. Their willingness to share this information has contributed to the quality and richness of this publication. Further information:
Surgical Education Research & Training Institute Royal North Shore Hospital St Leonards NSW 2065 Australia
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Published June 2025
CONTENTS
Executive Summary
page 1
Anaesthesia
page 2
Breast & Melanoma Surgery
page 6
Burns, Plastics & Reconstructive Surgery
page 9
Cardiothoracic Surgery
page 11
Colorectal Surgery
page 13
Endocrine Surgery
page 16
Hand & Peripheral Nerve Surgery
page 20
Intensive Care Unit
page 24
Neurosurgery
page 31
Neurointervention Unit
page 33
Ophthalmology
page 35
Orthopaedic Surgery
page 39
Otolaryngology Head & Neck Surgery
page 45
Trauma Service
page 47
Upper Gastrointestinal Surgery
page 49
Urological Surgery
page 56
Vascular Surgery
page 59
EXECUTIVE SUMMARY
The Royal North Shore Hospital (RNSH) Surgical Education Research and Training (SERT) Institute is proud to present the third edition of the RNSH Research Activity Report 2023-2024. The report provides an overview of the research activity undertaken by clinicians within the Division of Surgery and Anaesthesia (DoSA) at RNSH over a two-year period. The inaugural research activity report published in 2021, showcased research authored by RNSH surgeons over three years from 2018-2020. Following recognition of this work, subsequent iterations incorporate research from all departments across the division from 2021-2024, including Anaesthesia, Intensive Care Unit (ICU), the Trauma Service, Allergy Clinic and Acute Pain Management. The RNSH Research Activity Report 2023-2024 is the third iteration in this series and continues to highlight the significant volume of research activity and peer-reviewed publications across the DoSA in 2023-2024.
In 2023-2024, a total of 614 manuscripts were published, averaging 307 publications per year.
We hope you enjoy reading this report as you explore the volume of research undertaken across the DoSA at RNSH.
Professor Thomas Hugh Director, SERT Institute
Ellie McCann Manager, SERT Institute
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ANAESTHESIA (INCLUDES: ALLERGY CLINIC AND ACUTE PAIN MANAGEMENT) Head of Department: Ben Olesnicky and Jonothon Brock
RESEARCH AND EDUCATION SUPERVISION
Sarah Green •
Senior Lecturer, University of Sydney
Associate Professor Matthew Doane • 2 PhD students • Supervisor, MD Program, University of Sydney
DEPARTMENTAL RESEARCH RESOURCES
CLINICAL DATABASES TO SUPPORT OUTCOMES RESEARCH • Australian and New Zealand Anaesthetic Allergy Group (ANZAAG) • The NSW Trauma Registry • Perioperative Medicine • Perioperative Allergy Database
CURRENT RESEARCH ACTIVITY
Clinical Trials • Chewing gum versus ondansetron for post-operative nausea and vomiting in women and girls having laparoscopic or breast surgery (Chewy) • MAnagement of Systolic blood pressure during Thrombectomy by Endovascular Route for acute ischaemic STROKE (MASTERSTROKE) • Investigation of massive transfusion practice and development of an experimental clinical decision support system • The feasibility of implementing a validated fatigue risk management system for Junior Medical Staff on nightshift • Long-term Outcomes of Lidocaine Infusions for PostOperative Pain (LOLIPOP) • Orthostatic hypotension in the post anaesthesia care unit as a predictor for delayed mobilisation post lower limb arthroplasty • Validation of a scoring tool for suspected perioperative immediate hypersensitivity reactions using case referrals to Royal North Shore perioperative Allergy Clinic • Perioperative analgesia for major abdominal surgery • Opioid neuraxial analgesia for major open abdominal surgery: a feasibility study using a combination of intrathecal and epidural morphine • Rib fracture intervention study
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Clinical Research • The relationship between clinical grade of perioperative anaphylaxis and serum tryptase level • Retrospective review of prior exposure to sugammadex during anaesthesia in patients who have confirmed sugammadex anaphylaxis • A five-year experience of paediatric perioperative anaphylaxis at a tertiary level mixed paediatric and adult anaesthetic allergy service in Sydney, Australia • Cefazolin Anaphylaxis: evaluation of persistence of sensitization up to 10 years after the sentinel event • Paediatric perioperative hypersensitivity: comparison of two tryptase formulae to support a diagnosis of mast cell activation • Peripherally Inserted Central Catheter (PICC) line service utilisation study • Code crimson activation and outcomes study • Acute rib fracture management study • Linking data between perioperative drug allergy services in the ANZAAG network • Development of cost-efficient and effective intravenous drug challenge protocols in perioperative drug allergy • Assessment of maximal non-irritant concentrations of cisatracurium in intradermal drug allergy testing • Evaluation of clinical scoring tools to assist diagnosis and triage in perioperative allergy • Skin testing - in vitro testing and drug provocation testing for diagnosis and management of drug allergy
PUBLICATIONS
20242
Arenas-Castro et al. 2024 “Academic publishing requires linguistically inclusive policies.” Proc Biol Sci 291: 20232840 PMID:38471557 Anaesthesia Staff: Supriya Chowdhury Armstrong et al. 2024 “Management of Patients With Refractory Reflux-Like Symptoms Despite Proton Pump Inhibitor Therapy: Evidence-Based Consensus Statements.” Aliment Pharmacol Ther 61: 636-650 PMID:39740235 Anaesthesia Staff: Paul Sinclair Ashton-James et al. 2024 “Efficacy of an mHealth intervention to support pain self-management and improve analgesia in patients with rib fractures: protocol for a randomised controlled trial.” BMJ Open 14: e086202 PMID:39510779 Anaesthesia Staff: Matthew Doane, Paul Glare, Damien Finniss Chlap et al. 2024 “Uncertainty estimation using a 3D probabilistic U-Net for segmentation with small radiotherapy clinical trial datasets.” Comput Med Imaging Graph 116: 102403 PMID:38878632 Anaesthesia Staff: Jennifer Tan Chuan et al. 2024 “Using Virtual Reality to teach ultrasound-guided needling skills for regional anaesthesia: A randomised controlled trial.” J Clin Anesth 97: 111535 PMID:38889487 Anaesthesia Staff: Supriya Chowdhury Cook et al. 2024 “Modified Circuit for Left-Sided Heart Bypass in Thoracoabdominal Surgery.” Ann Thorac Surg Short Rep 2: 21-24 PMID:39790259 Anaesthesia Staff: Andy Wang, Bruce Adendorff Cornall et al. 2024 “Management of pain in cancer patients- lessons from practices during the COVID-19: a qualitative study of cancer care providers' perspectives.” BMC Health Serv Res 24: 232 PMID:38388905 Anaesthesia Staff: Paul Glare, Andy Wang Dionne et al. 2024 “Canadian Spine Society: 24th Annual Scientific Conference, Wednesday, February 28 - Saturday, March 2, Fairmont Chateau Whistler, Whistler, B.C., Canada.” Can J Surg 67: S17-S76 PMID:39537311 Anaesthesia Staff: Andrew Howard; Charles Fisher (Vascular) , Ragavan Manoharan (Neurosurgery) Elhage et al. 2024 “The effect of adductor canal block on outcomes of total knee arthroplasty: A single centre, historical cohort study.” J Orthop 65: 31-35 PMID:39801907 Anaesthesia Staff: Ben Olesnicky Ferreira et al. 2024 “How is postoperative pain after hip and knee replacement managed? An analysis of two large hospitals in Australia.” Perioper Med (Lond) 13: 49 PMID:38822448 Anaesthesia Staff: Paul Glare Gholamrezaei et al. 2024 “A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial.” Pain Rep 9: e1128 PMID:38352024 Anaesthesia Staff: Paul Glare Glare et al. 2024 “Chronic pain in cancer survivors improved after learning pain self-management techniques in an Australian pain clinic.” Pain Med 25: 578-580 PMID:38775651 Anaesthesia Staff: Paul Glare
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Green et al. 2024 “Serum tryptase changes in children with suspected perioperative hypersensitivity. Comment on BJA Open 2024; 9: 100254.” BJA Open 12: 100307 PMID:39310274 Anaesthesia Staff: Sarah Green, Ben Krupowicz, Marc Capon, Andrew Lindberg, Anisha Kulkarni, Jamma Li Hamilton et al. 2024 “Effectiveness of Interventions to Reduce Opioid Use After Orthopaedic Surgery: A Systematic Reviewof Randomised Controlled Trials.” Drugs 85: 385-396 PMID:39702868 Anaesthesia Staff: Andy Wang Hesam-Shariati et al. 2024 “A home-based self-directed EEG neurofeedback intervention for people with chronic neuropathic pain following spinal cord injury (the StoPain Trial): description of the intervention.” Spinal Cord 62: 658-666 PMID:39266672 Anaesthesia Staff: Paul Glare Kernick et al. 2024 “Prevalence and management of chronic nonmalignant pain in palliative care populations: A systematic review.” Palliat Support Care 22: 840-846 PMID:37039456 Anaesthesia Staff: Paul Glare Lee et al. 2024 “The use of interventional procedures for cancer pain. A brief review.” Support Care Cancer 32: 285 PMID:38607568 Anaesthesia Staff: Andy Wang Moi et al. 2024 “Validation of the American College of Surgeons National Surgical Quality Improvement Program risk predictor in an Australian general surgical cohort.” ANZ J Surg 94: 108-116 PMID:37792672 Anaesthesia Staff: Ben Olesnicky, Andy Wang, Michelle Mulligan Oguchi et al. 2024 “Psychologically based interventions for adults with chronic neuropathic pain: a scoping review.” Pain Med 25: 400-414 PMID:38310361 Anaesthesia Staff: Paul Wrigley O'Rourke et al. 2024 “Orbital Cellulitis Secondary to Dacryocystitis: A Case Series and Literature Review.” Ophthalmic Plast Reconstr Surg : PMID:39652518 Anaesthesia Staff: Jennifer Tan, Brett O'Donnell (Opthalmology) Patanwala et al. 2024 “Antibiotic De-Escalation Practices in the Intensive Care Unit: A Multicenter Observational Study.” Ann Pharmacother 59: 311-318 PMID:39192570 Anaesthesia Staff: Sarah Green Pedersen et al. 2024 “Perioperative anaphylaxis and the principle of primum non nocere.” Br J Anaesth 132: 1190-1193 PMID:38677945 Anaesthesia Staff: Sarah Green Tran et al. 2024 “Construction and optimization of multi-platform precision pathways for precision medicine.” Sci Rep 14: 4248 PMID:38378802 Anaesthesia Staff: Andy Wang
2023
Chee et al. 2023 “Comparison of three analgesic regimens in women undergoing cervical brachytherapy.” Brachytherapy 22: 607-615 PMID:37423807 Anaesthesia Staff: Leonie Watterson Christensen et al. 2023 “Embracing multiple stakeholders' perspectives in defining competent simulation facilitators' characteristics and educational behaviours: a qualitative study from Denmark, Korea, and Australia.” Adv Simul (Lond) 8: 1 PMID:36624547 Anaesthesia Staff: Leonie Watterson Deng et al. 2023 “Use of adrenaline to manage suspected anaphylaxis following COVID-19 vaccination: An Australian retrospective cohort study.” Vaccine 41: 5987-5993 PMID:37633752 Anaesthesia Staff: Jamma Li Doane et al. 2023 “Quantifying exposure to chlorhexidine from decontamination of peripheral intravenous injection ports.” Acta Anaesthesiol Scand 67: 356-363 PMID:36547232 Anaesthesia Staff: Matthew Doane Ekelund et al. 2023 “Evaluation of the simulation based training quality assurance tool (SBT-QA10) as a measure of learners' perceptions during the action phase of simulation.” BMC Med Educ 23: 290 PMID:37127593 Anaesthesia Staff: Leonie Watterson Gholamrezaei et al. 2023 “Text messaging intervention to support patients with chronic pain during prescription opioid tapering: protocol for a double-blind randomised controlled trial.” BMJ Open 13: e073297 PMID:37879692 Anaesthesia Staff: Paul Glare Gholamrezaei et al. 2023 “A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial.” medRxiv : PMID:37214982 Anaesthesia Staff: Paul Glare Glare et al. 2023 “Tolerability and Efficacy of a 10:25 Preparation of 9-Tetrahydrocannabinol and Cannabidiol for Treatment of Chronic Back or Neck Pain: A Multiple-Dose Escalation Study.” Med Cannabis Cannabinoids 6: 66-76 PMID:37465637 Anaesthesia Staff: Paul Glare Khuong et al. 2023 “Paraprotein associated heparin resistance during cardiopulmonary bypass.” Perfusion 38: 1319-1321 PMID:35700111 Anaesthesia Staff: Arpit Srivastava; Levi Bassin (Cardiothoracic) Li et al. 2023 “Skin Testing and Basophil Activation Testing Is Useful for Assessing Immediate Reactions to Polyethylene Glycol-Containing Vaccines.” Vaccines (Basel) 11: PMID:36851130 Anaesthesia Staff: Jamma Li Li et al. 2023 “Australasian Consensus Statement on the Identification, Prevention, and Management of Hormonal Crises in Patients with Neuroendocrine Neoplasms Undergoing Peptide Receptor Radionuclide Therapy.” Neuroendocrinology 113: 281-288 PMID:36049462 Anaesthesia Staff: John Leyden
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Lian et al. 2023 “A Prospective Study of Electromyographic Amplitude Changes During Intraoperative Neural Monitoring for Open Thyroidectomy.” World J Surg 47: 1971-1977 PMID:37005926 Anaesthesia Staff: Sonya Bajenov; Mark Sywak (Endocrine) Loo et al. 2023 “Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment- resistant depression (KADS study): randomised double-blind active-controlled trial.” Br J Psychiatry 223: 533-541 PMID:38108319 Anaesthesia Staff: John Leyden Marroquin-Harris et al. 2023 “Aspiration risk with glucagon-like peptide 1 (GLP-1) agonists.” Anaesthesia 78: 1524 PMID:37443429 Anaesthesia Staff: Mincho Marroquin-Harris, Ben Olesnicky Novakovic et al. 2023 “Microlaryngeal Laser Surgery Using High-flow Nasal Ventilation at Two Oxygen Concentration Deliveries.” Laryngoscope 133: 634-639 PMID:35775633 Anaesthesia Staff: Stefan Liew Payne et al. 2023 “Depth of anaesthesia and mortality after cardiac or noncardiac surgery: a systematic review and meta- analysis of randomised controlled trials.” Br J Anaesth 130: e317-e329 PMID:36210184 Anaesthesia Staff: Andy Wang Pinto et al. 2023 “Follow-up of penicillin allergy labels 1 year after successful penicillin delabeling.” Ann Allergy Asthma Immunol 130: 80-83.e3 PMID:36116749 Anaesthesia Staff: Jamma Li Pirie et al. 2023 “Postoperative analgesia for upper gastrointestinal surgery: a retrospective cohort analysis.” Perioper Med (Lond) 12: 40 PMID:37464387 Anaesthesia Staff: Andy Wang, Matthew Doane Turner et al. 2023 “Similarities in consciousness occurring during sleep and sedation.” Br J Anaesth 131: 632-633 PMID:37718091 Anaesthesia Staff: Andrew Turner Woldendorp et al. 2023 “Perioperative transfusion and long-term mortality after cardiac surgery: a meta-analysis.” Gen Thorac Cardiovasc Surg 71: 323-330 PMID:36884106 Anaesthesia Staff: Arpit Srivastava, Matthew Doane; Levi Bassin, David Marshman (Cardiothoracic)
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BREAST AND MELANOMA SURGERY Head of Department: Katrina Moore
RESEARCH AND EDUCATION SUPERVISION
Katrina Moore •
Senior Lecturer, University of Sydney
• Supervisor, Medical Student Program – Oncology Block, University of Sydney • Supervisor, Accredited Registrar Training Program, University of Sydney Samriti Sood • Teaching and Course Coordinator, Advanced Surgery of the Breast - Master of Surgery, University of Sydney Professor Andrew Spillane • Teaching and Head of Course, Advanced Surgery of the Breast - Master of Surgery, University of Sydney
DEPARTMENTAL RESEARCH RESOURCES
CLINICAL DATABASES TO SUPPORT OUTCOMES RESEARCH • Breast High Risk Database • Breast Total Practice Audit • BreastSurgANZ Quality Audit (BQA) • Melanoma Research Database (MRD) - Melanoma Institute Australia LINKS TO TRANSLATIONAL RESEARCH PARTNERS OR UNIVERSITY DEPARTMENTS • Melanoma Institute Australia • University of Sydney – Discipline of Surgery • Kolling Research Institute
CURRENT RESEARCH ACTIVITY
• Clinical and laboratory-based research in melanoma and breast cancer • Outcomes of targeted axillary clearance in early node positive breast cancer following neoadjuvant chemotherapy • Breast screening in patients with neurofibromatosis • Staging investigations in high-risk patients and their subsequent follow-up • Development of a multidisciplinary and functional breast database for northern campus • A randomised phase III trial of adjuvant radiation therapy versus observation following breast conserving surgery and endocrine therapy in patients with molecularly characterised luminal - an early breast cancer (EXPERT) • An open label, randomized, window of opportunity study between diagnosis and definite surgery, to assess the effect of antiestrogen therapies, alone and in combination with microionized progesterone (prometrium) in patients with newly diagnosed ER+PR+ breast cancer (WinPRO) • Improving Breast Reconstruction Equity of Access through Stakeholder consultation and Translation into policy and practice (iBREAST)
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• Prospective cohort study to look at the impact of the choice of breast reconstruction (immediate, delayed or none) on quality-of-life measures and clinical outcomes for women undergoing mastectomy and PMRT for breast cancer (QoLID Study) • Investigate the effectiveness of using Denosumab to decrease or prevent the risk of developing breast cancer in women who carry a BRCA1 gene mutation (BRCA-P).
PUBLICATIONS
2024
Blank et al. 2024 “Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma.” N Engl J Med 391: 1696-1708 PMID:38828984 Surgical Staff: Andrew Spillane Dempsey et al. 2024 “Patient and Staff Experiences of Embedding Electronic Patient Reported Outcome Measures for Distress Screening and Quality of Life Assessment, Into Routine Melanoma Care: A Mixed-Methods Study.” Psychooncology 33: e70053 PMID:39694881 Surgical Staff: Andrew Spillane Gjorup et al. 2024 “Role of Concurrent Ultrasound Surveillance of Sentinel Node-Positive Node Fields in Melanoma Patients Having Routine Cross-Sectional Imaging.” Ann Surg Oncol 31: 1857-1864 PMID:37966706 Surgical Staff: Andrew Spillane Jiang et al. 2024 “Exploring locoregional treatment reporting in neoadjuvant systemic breast cancer treatment studies: A systematic review.” Eur J Surg Oncol 50: 108554 PMID:39059194 Surgical Staff: Andrew Spillane Lee et al. 2024 “ASO Author Reflections: Lymphoedema Related to Inguinal and Ilioinguinal Lymphadenectomy for Melanoma.” Ann Surg Oncol 31: 4071-4072 PMID:38536583 Surgical Staff: Andrew Spillane Lee et al. 2024 “Leg Lymphoedema After Inguinal and Ilio-Inguinal Lymphadenectomy for Melanoma: Results from a Prospective, Randomised Trial.” Ann Surg Oncol 31: 4061-4070 PMID:38494565 Surgical Staff: Andrew Spillane Long et al. 2024 “Neoadjuvant pembrolizumab, dabrafenib and trametinib in BRAFV600-mutant resectable melanoma: the randomized phase 2 NeoTrio trial.” Nat Med 30: 2540-2548 PMID:38907159 Surgical Staff: Andrew Spillane Mann et al. 2024 “Postoperative radiotherapy omission in selected patients with early breast cancer following preoperative breast MRI (PROSPECT): primary results of a prospective two-arm study.” Lancet 403: 261-270 PMID:38065194 Surgical Staff: Andrew Spillane Menzies et al. 2024 “Five-year analysis of neoadjuvant dabrafenib and trametinib for stage III melanoma.” Ann Oncol 35: 739-746 PMID:38754780 Surgical Staff: Andrew Spillane Novis et al. 2024 “Clinical significance of intra-thoracic and intra-abdominal sentinel lymph nodes detected on lymphoscintigraphy in truncal melanoma patients.” Eur J Surg Oncol 51: 109538 PMID:39662108 Surgical Staff: Andrew Spillane Ofri et al. 2024 “Optimising the targeted axillary dissection in breast cancer: marker type and timing variability.” Gland Surg 13: 1878-1882 PMID:39544982 Surgical Staff: Andrew Spillane Ofri et al. 2024 “Current bi-national attitudes towards targeted axillary dissection.” ANZ J Surg 94: 11-13 PMID:38149761 Surgical Staff: Andrew Spillane Ofri et al. 2024 “The complexities of establishing a surgical multi-centre registry in Australia: challenges, and possible solution.” ANZ J Surg 94: 1444-1446 PMID:38995075 Surgical Staff: Andrew Spillane Potter et al. 2024 “Protocol for the development of a core outcome set and reporting guidelines for locoregional treatment in neoadjuvant systemic breast cancer treatment trials: the PRECEDENT project.” BMJ Open 14: e084488 PMID:38643011 Surgical Staff: Andrew Spillane Reijers et al. 2024 “Impact of personalized response-directed surgery and adjuvant therapy on survival after neoadjuvant immunotherapy in stage III melanoma: Comparison of 3-year data from PRADO and OpACIN-neo.” Eur J Cancer 214: 115141 PMID:39602990 Surgical Staff: Andrew Spillane Varey et al. 2024 “Predicting Recurrence-Free and Overall Survival for Patients With Stage II Melanoma: The MIA Calculator.” J Clin Oncol 42: 1169-1180 PMID:38315961 Surgical Staff: Andrew Spillane Winder et al. 2024 “ASO Author Reflections: Impact of an Online Risk Calculator for Sentinel Node Positivity on Management of Patients with T1 and T2 Melanomas.” Ann Surg Oncol 31: 5352-5353 PMID:38874872 Surgical Staff: Andrew Spillane Winder et al. 2024 “Impact of an Online Risk Calculator for Sentinel Node Positivity on Management of Patients with T1 and T2 Melanomas.” Ann Surg Oncol 31: 5331-5339 PMID:38802717 Surgical Staff: Andrew Spillane
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Zijlker et al. 2024 “The Effect of Neoadjuvant Systemic Therapy on Surgical Outcomes After Lymph Node Dissections for Stage III Melanoma; An Australian Cohort.” Ann Surg Oncol 31: 5324-5330 PMID:38762644 Surgical Staff: Andrew Spillane
2023
Dayaratna et al. 2023 “Trends and variations in post-mastectomy breast reconstruction rates in Australia over 10 years.” ANZ J Surg 93: 242-250 PMID:36651629 Surgical Staff: Andrew Spillane Dempsey et al. 2023 “Patient-reported health-related quality of life outcomes following mastectomy for breast cancer, with immediate, delayed or no breast reconstruction: Four-year follow-up from a prospective cohort study.” Breast 71: 122-131 PMID:37573653 Surgical Staff: Andrew Spillane Dempsey et al. 2023 “Benefits and harms of breast cancer screening revisited: a large, retrospective cross-sectional study quantifying treatment intensity in women with screen-detected versus non-screen-detected cancer in Australia and New Zealand.” BMJ Oncol 2: e000100 PMID:39886492 Surgical Staff: Andrew Spillane Holtkamp et al. 2023 “Adjuvant radiotherapy after salvage surgery for melanoma recurrence in a node field following a previous lymph node dissection.” J Surg Oncol 128: 97-104 PMID:36971691 Surgical Staff: Andrew Spillane Mao et al. 2023 “Cross-platform comparison of immune signatures in immunotherapy-treated patients with advanced melanoma using a rank-based scoring approach.” J Transl Med 21: 257 PMID:37055772 Surgical Staff: Andrew Spillane Miller et al. 2023 “Improving Selection for Sentinel Lymph Node Biopsy Among Patients With Melanoma.” JAMA Netw Open 6: e236356 PMID:37074717 Surgical Staff: Andrew Spillane Nickel et al. 2023 “Women's views about current and future management of Ductal Carcinoma in Situ (DCIS): A mixed- methods study.” PLoS One 18: e0288972 PMID:37478123 Surgical Staff: Andrew Spillane Paver et al. 2023 “Utility of next generation sequencing for differentiating malignant PEComa from metastatic melanoma.” Pathology 55: 555-560 PMID:36400594 Surgical Staff: Andrew Spillane Paver et al. 2023 “Prognostic Significance of Incipient Ulceration in Primary Cutaneous Melanoma.” JAMA Dermatol 159: 1359-1367 PMID:37910123 Surgical Staff: Andrew Spillane Reijers et al. 2023 “IFN- γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma.” J Exp Med 220: e20221952 PMID:36920329 Surgical Staff: Andrew Spillane Schoenfeldt et al. 2023 “Prognostic Significance and Management of Sentinel Nodes in the Triangular Intermuscular Space of Patients with Melanoma.” Ann Surg Oncol 30: 2354-2361 PMID:36463358 Surgical Staff: Andrew Spillane Wilding et al. 2023 “Clinical and imaging modality factors impacting radiological interpretation of breast screening in young women with neurofibromatosis type 1.” Fam Cancer 22: 499-511 PMID:37335380 Surgical Staff: Katrina Moore
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BURNS, PLASTICS & RECONSTRUCTIVE SURGERY Head of Department: Rowan Gillies
RESEARCH AND EDUCATION SUPERVISION
Varun Harish • Supervisor, MD Program, University of Sydney • Supervisor, Master of Surgery, University of Sydney • Supervisor, MD Applied Research Project, University of Notre Dame
DEPARTMENTAL RESEARCH RESOURCES
CLINICAL DATABASES TO SUPPORT OUTCOMES RESEARCH • State-wide Burn Injury Service (SBIS) Registry • Burns Registry Australia and New Zealand (BRANZ) • Plastic Surgery Department Database
CURRENT RESEARCH ACTIVITY
• Pleomorphic dermal sarcoma: the effect of surgical and histological margins on clinical outcomes • Histological margin clearance in cutaneous squamous cell carcinoma • Cost-benefit analysis of Novosorb BTM in burn injuries • The impact of core body temperature on clinical outcomes in severe burn injuries • Treatment of atypical lipomatous tumours: a systematic review • Skin neoplasia – clinical and pathologic aspects in diagnosis and management of skin tumours in the Australian population • The effect of indocyanine green video angiography on short-term and long-term clinical outcomes in burn injuries: a randomised controlled trial
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PUBLICATIONS
2024
Cheung et al. 2024 “The effect of CREST syndrome in planning a DIEP flap reconstruction.” ANZ J Surg 94: 474-475 PMID:38054306 Surgical Staff: Bishoy Soliman Chia et al. 2024 “Reconstruction of a Large Composite Hemicraniofacial Defect with Bipedicled DIEP/TRAM Flaps.” Plast Reconstr Surg Glob Open 12: e5713 PMID:38596576 Surgical Staff: Bishoy Soliman Diab et al. 2024 “The impact of COVID-19 on adult burns: A statewide review of epidemiology and clinical outcomes.” Burns 50: 381-387 PMID:37996282 Surgical Staff: Jeon Cha Haines etal. 2024 “Intraoperative computed tomography for the management of traumatic complex facial fractures: a narrative review." Australasian Journal of Plastic Surgery 7 :1 Surgical Staff: Marc Langbart Karunaratne et al. 2024 “Anti factor Xa monitoring for venous thromboprophylaxis in severely burn-injured patients: A systematic review.” Burns 50: 1713-1718 PMID:38981800 Surgical Staff: Varun Harish Kim et al. 2024 “How to do a hip disarticulation.” ANZ J Surg 53: e783-e789 PMID:39641379 Surgical Staff: Rowan Gillies, Varun Harish Noori et al. 2024 “Chemical burns to scalp from hair bleach: a retrospective case series.” Australasian Journal of Plastic Surgery 7 :2 Surgical Staff: Jeon Cha Yeap et al. 2024 “The pedicled fillet-of-sole flap as a reconstructive option for stump reconstruction in chronic osteomyelitis.” ANZ J Surg 94: 267-269 PMID:37905721 Surgical Staff: Bishoy Soliman, Michael Symes (Orthopaedics)
2023
Bishay et al. 2023 “Cutaneous zygomycosis: a poor prognostic indicator in burns patients.” ANZ J Surg 93: 2527-2528 PMID:37128665 Surgical Staff: Bishoy Soliman, Rowan Gillies Cheung et al. 2023 “The impact of overseas cosmetic surgery on our public hospital system.” ANZ J Surg 93: 435 PMID:36660870 Surgical Staff: Bishoy Soliman Cheung et al. 2023 “Deep Inferior Epigastric Artery (DIEP) anomaly in autologous breast reconstruction.” ANZ J Surg 93: 1082-1083 PMID:36251399 Surgical Staff: Bishoy Soliman Haines et al. 2023 “The burn injury transfer feedback form: A 16 year Australian statewide review of burn inter-hospital transfer.” Burns 49: 961-972 PMID:35728985 Surgical Staff: Bishoy Soliman, Jeon Cha, Varun Harish Huang et al. 2023 “The prognostic significance of lymphovascular invasion in cutaneous squamous cell carcinoma.” ANZ J Surg 93: 2727-2735 PMID:37727039 Surgical Staff: Varun Harish Jung et al. 2023 “Management strategies for perioperative anaemia in the severely burn-injured Jehovah's Witness patients who decline a blood transfusion: A systematic review with illustrative case reports.” Burns 49: 716-729 PMID:35941026 Surgical Staff: Varun Harish, Rowan Gillies Lo et al. 2023 “Case report: Management of infiltrative basosquamous carcinoma of the sternum.” Int J Surg Case Rep 106: 108107 PMID:37060762 Surgical Staff: Marc Langbart Sritharan et al. 2023 “Temporal trends in burn size estimation and the impact of the NSW Trauma App on estimation accuracy.” Burns 49: 1403-1411 PMID:36878736 Surgical Staff: Bishoy Soliman, Jeon Cha, Varun Harish
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CARDIOTHORACIC SURGERY Head of Department: Michael Harden
DEPARTMENTAL RESEARCH RESOURCES
CLINICAL DATABASES TO SUPPORT OUTCOMES RESEARCH • Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) National Database • RNSH Cardiovascular Surgery Database • Implantable Cardiac Device Database
CURRENT RESEARCH ACTIVITY
• Enhanced Recovery After Surgery (ERAS) protocol - collaborative project to optimise perioperative care of cardiac surgical patients • Artificial Intelligence (AI) tool development for predicting cardiothoracic ward patients that are likely to deteriorate (with Sydney Adventist Hospital) • Development of a RNSH implantable cardiac device database to record all cases performed • Long term follow-up (10-15 years) of off-pump arterial grafts and projects related to assessing and improving off-pump surgery • Bio-printing of human cardiac patches to improve heart regeneration • Evaluating use of aortic cannulation in valve replacement • Investigating axillary inflow cerebral injury in patients undergoing aortic valve replacement • Vascular leak associated micro-RNA in cardiovascular surgery • Determining trans-catheter aortic valve implantation outcomes in low-risk patients • A study of flow dynamics in Coronary Artery Bypass Grafts developing a model to predict the flow based on which conduit, coronary distribution and graft configuration
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PUBLICATIONS
2024
Caterson et al. 2024 “An unusual case of persistent consolidation: Idiopathic lymphoid interstitial pneumonia.” Respirol Case Rep 12: e01408 PMID:38860176 Surgical Staff: Michael Harden Chang et al. 2024 “Iatrogenic tracheal rupture in the elderly: a case report and review of tracheobronchial repair techniques.” J Surg Case Rep 2024: rjae550 PMID:39211364 Surgical Staff: Michael Harden
2023
Bassin et al. 2023 “The implementation of a real time early warning system using machine learning in an Australian hospital to improve patient outcomes.” Resuscitation 188: 109821 PMID:37150397 Surgical Staff: Levi Bassin Cook et al. 2023 “Aortic arch impingement with Salter Harris II epiphyseal fracture of the medial clavicle: A novel use of video assisted thoracoscopy.” Trauma Case Rep 46: 100856 PMID:37333493 Surgical Staff: Peter Brady GBD 2019 Lip, Oral and Pharyngeal Cancer Collaborators et al. 2023 “The Global, Regional, and National Burden of Adult Lip, Oral, and Pharyngeal Cancer in 204 Countries and Territories: A Systematic Analysis for the Global Burden of Disease Study 2019.” JAMA Oncol 9: 1401-1416 PMID:37676656 Surgical Staff: Manu Mathur; Timothy Roberts , Kimberley Tan (Ophthalmology) Khuong et al. 2023 “Paraprotein associated heparin resistance during cardiopulmonary bypass.” Perfusion 38: 1319-1321 PMID:35700111 Surgical Staff: Levi Bassin Manuel et al. 2023 “Aortobronchial fistula presenting with frank haemoptysis.” ANZ J Surg 93: 1375-1376 PMID:36413042 Surgical Staff: Levi Bassin Woldendorp et al. 2023 “Perioperative transfusion and long-term mortality after cardiac surgery: a meta-analysis.” Gen Thorac Cardiovasc Surg 71: 323-330 PMID:36884106 Surgical Staff: Levi Bassin, David Marshman; Matthew Doane (Anaesthesia)
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COLORECTAL SURGERY Head of Department: Yasser Salama
RESEARCH AND EDUCATION SUPERVISION
Professor Alexander Engel • 3 PhD Students • 2 Master Students • 4 MD Research Students Professor Margaret Schnitzler • 3 PhD Students • 1 MPhil Student • 1 MD Research Student •
Head of Northern Clinical School
• Academic Director (Medicine/Dentistry) Northern Precinct • Academic Lead for Surgery at Northern Clinical School • Co-Director of MD Education Specialty of Surgery Kah Hoong Chang • Supervisor, MD Program, University of Sydney • Academic Lead, Departmental Postgraduate Research Program • Clinical Senior Lecturer, University of Sydney
DEPARTMENTAL RESEARCH RESOURCES
CLINICAL DATABASES TO SUPPORT OUTCOMES RESEARCH • RNSH Colorectal Audit • Bi-National Colorectal Cancer Audit (BCCA) • Colorectal Cancer Surgical Pathology Database LINKS TO TRANSLATIONAL RESEARCH PARTNERS OR UNIVERSITY DEPARTMENTS • Nano Institute, University of Sydney • Charles Perkins Centre, University of Sydney • Nano Photonics Institute, University of NSW • University of Technology Sydney • University of Newcastle • Chinese University of Hong Kong
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CURRENT RESEARCH ACTIVITY
• Photodynamic therapy in combination with low dose radiotherapy as an alternative to chemoradiation in advanced and recurrent rectal cancer • Integrative molecular classification of colorectal polyps • Molecular signature of lymph node metastasis in early colorectal cancer • Assessing and improving emotional intelligence in surgeons and surgical trainees • Muscle map (convolutional neural network) of the pelvic floor • Obstetric anal sphincter injury • Novel therapies and investigations in anorectal disorders • DOTATATE surveillance in low grade resected small bowel neuroendocrine tumour • Neuroendocrine tumour resection • Young onset colorectal cancer • Contemporary rectal cancer management • Rectal cancer watch and wait programme: a collaborative study across 7 LHDs • Reducing carbon footprint in colorectal surgery • TreatmENT of AnastomotiC LeakagE after Colon cancer resection (The TENTACLE – Colon study): an international multicentre study • Colorectal cancer biobank and translational research programme • Microbiomic analysis in colorectal neoplasia • PREDICT study: circulating tumour DNA in rectal cancer • Diverticulitis recurrence • Analysis of patients presenting with haematochezia/PR bleeding at a single centre • CT and clinical correlation of diverticulitis severity • IMAP colorectal polyp study • Hide and Seek: Multidisciplinary team advice and subsequent genetic counselling for suspected Lynch syndrome • Clinicopathological factors affecting survival in young onset colorectal cancers • Enhancing accuracy of post-neoadjuvant therapy response assessment in rectal cancer • Treatment of anastomotic leakage after colon cancer • Predictors of metachronous bowel neoplasia
PUBLICATIONS
2024
Kleinig et al. 2024 “Environmental impact of large language models in medicine.” Intern Med J 54: 2083-2086 PMID:39542015 Surgical Staff: Margaret Schnitzler McKay et al. 2024 “MuscleMap: An Open-Source, Community-Supported Consortium for Whole-Body Quantitative MRI of Muscle.” J Imaging 10: 262 PMID:39590726 Surgical Staff: Margaret Schnitzler Mohtashami et al. 2024 “Idiopathic myointimal hyperplasia of the mesenteric veins: a rare and poorly understood disease.” ANZ J Surg 94: 478-480 PMID:38010844 Surgical Staff: Yasser Salama Rickard et al. 2024 “Emotional Intelligence as a Component of Surgical Coaching: A Scoping Review.” J Surg Educ 82: 103316 PMID:39602949 Surgical Staff: Margaret Schnitzler Sarofim et al. 2024 “National screening for colorectal cancer is associated with stage shift to earlier diagnosis.” ANZ J Surg 94: 1279-1285 PMID:38553882 Surgical Staff: Justin Evans Siriwardena et al. 2024 “Clozapine-Induced Refractory Colonic Pseudo-Obstruction.” Cureus 16: e53377 PMID:38435172 Surgical Staff: Shahrir Kabir Trieu et al. 2024 “Management After Obstetric Anal Sphincter Injury: Anorectal Manometry and Symptoms Predict Long-Term Fecal Incontinence.” Am J Gastroenterol : PMID:39248599 Surgical Staff: Margaret Schnitzler
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2023
Jambor et al. 2023 “Complete transection of the descending colon following blunt abdominal trauma.” BMJ Case Rep 16: e254553 PMID:37280009 Surgical Staff: Rebecca Seton Malhi et al. 2023 “Tagging psychopathology by being more analytical?” Bipolar Disord 25: 162-163 PMID:36478503 Surgical Staff: Margaret Schnitzler Mazor et al. 2023 “The patient with obstructed defecatory symptoms: Management differs considerably between physicians and surgeons.” Neurogastroenterol Motil 35: e14592 PMID:37036403 Surgical Staff: Margaret Schnitzler Rickard et al. 2023 “Outcomes of Emotional Intelligence Training for Surgeons in a Real-World Setting: a Mixed Methods Study.” J Surg Educ 80: 1445-1453 PMID:37612198 Surgical Staff: Margaret Schnitzler Trieu et al. 2023 “Using a footstool does not aid simulated defecation in undifferentiated constipation: A randomized trial.” Neurogastroenterol Motil 35: e14580 PMID:36989181 Surgical Staff: Margaret Schnitzler Tse et al. 2023 “CD11c+ and IRF8+ cell densities in rectal cancer biopsies predict outcomes of neoadjuvant chemoradiotherapy.” Oncoimmunology 12: 2238506 PMID:37485033 Surgical Staff: Justin Evans Trieu et al. 2023 “Flatus Incontinence and Fecal Incontinence: A Case-Control Study.” Dis Colon Rectum 66: 591-597 PMID:35333800 Surgical Staff: Margaret Schnitzler Wang et al. 2023 “Evaluation of a modified emergency surgical acuity score in predicting operative and non-operative mortality and morbidity in an acute surgical unit.” ANZ J Surg 93: 2297-2302 PMID:37296520 Surgical Staff: Shahrir Kabir, Thomas Hugh (Upper GI)
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ENDOCRINE SURGERY Head of Department: Stanley Sidhu
RESEARCH AND EDUCATION SUPERVISION
Associate Professor Anthony Glover • University of Sydney supervision of higher degree research course completed • 4 MD Students • 1 MPH Student • 1 BA Student • Education and Research Lead, SERT Institute
Professor Stanley Sidhu • 2 MD Students • 3 PhD Students Clinical Associate Professor Mark Sywak • 1 MD Student • 2 Master of Surgery Students Alex Papachristos • Senior Lecturer, Surgery, University of Sydney • 2 MD Students • 1 Master of Surgery Student
DEPARTMENTAL RESEARCH RESOURCES
CLINICAL DATABASES TO SUPPORT OUTCOMES RESEARCH • Adrenal Surgery Database • Thyroid/Parathyroid Surgery Database • Thyroid Cancer Database • Follow up Database • Australian and New Zealand Thyroid Cancer Registry (ANZTCR) LINKS TO TRANSLATIONAL RESEARCH PARTNERS OR UNIVERSITY DEPARTMENTS
Garvan Institute (Genomics) Kolling Institute Cancer Genetics
• •
• Discipline of Surgery, University of Sydney • School of Biomedical Engineering, University of Technology Sydney
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CURRENT RESEARCH ACTIVITY
• Targeted nanoparticle therapy in medullary thyroid cancer and poorly differentiated thyroid cancer • Noncoding RNAs as diagnostic and therapeutic targets in adrenocortical cancer and neuroendocrine cancers • A novel covid vaccine for healthy volunteers and immunocompromised cancer patients – a comparative trial • Measurable outcomes in endocrine surgery to enhance global care • Garvan and University of Sydney Endocrine Cancer Program (ECP) – integrating endocrine patient care with genomic analysis • Comparisons of endocrine tumour recurrence • Studies of the influences of the long non-coding RNAs and micro-RNAs in cancer and cancer therapies • Study of thyroid cancer patients with distant metastasis (cohort study) • Alternative splicing and RBM10 mutations in advanced thyroid cancer (cohort study) • Prospective study of radio-frequency ablation for the management of benign thyroid nodular disease • Targeted neoadjuvant therapy for locally advanced thyroid cancer • Prospective study of nerve integrity monitoring in conventional thyroidectomy • Exploring resistance mechanisms to TKI therapy in advanced medullary thyroid cancer
PUBLICATIONS
2024
Aitken et al. 2024 “Codesign of health technology interventions to support best-practice perioperative care and surgical waitlist management.” BMJ Health Care Inform 31: e100928 PMID:38471784 Surgical Staff: Anthony Glover Aksoy et al. 2024 “Novel prognostic nomogram for predicting recurrence-free survival in medullary thyroid carcinoma.” Histopathology 84: 947-959 PMID:38253940 Surgical Staff: Anthony Glover, Alexander Papachristos, Stanley Sidhu, Mark Sywak D'souza et al. 2024 “The impact of delayed diagnosis and treatment due to COVID-19 on Australian thyroid cancer patients: a qualitative interview study.” BMJ Open 14: e069236 PMID:38626980 Surgical Staff: Anthony Glover Fenton et al. 2024 “Posterior retroperitoneal adrenalectomy for metastatic disease: a multi-site Australian series.” ANZ J Surg 95: 84-90 PMID:39540588 Surgical Staff: Mark Sywak Gild et al. 2024 “The Clinical Utility of Gallium-68-DOTATATE Positron Emission Tomography Scanning in Medullary Thyroid Cancer.” Endocr Pract 30: 218-224 PMID:38103829 Surgical Staff: Anthony Glover, Stanley Sidhu, Mark Sywak Glover et al. 2024 “Surgery for Locally Invasive Thyroid Cancer: Balancing Morbidity with Long Term Outcomes.” Ann Surg Oncol 32: 632-633 PMID:39557723 Surgical Staff: Anthony Glover Hashmi et al. 2024 “AGO2 protein: a key enzyme in the miRNA pathway as a novel biomarker in adrenocortical carcinoma.” Endocr Relat Cancer 31: e240061 PMID:39404265 Surgical Staff: Alexander Papachristos, Stanley Sidhu Lawless et al. 2024 “Anaplastic thyroid cancer: A review of recent evidence and summary of an Australian institutional protocol.” Asia Pac J Clin Oncol 20: 681-689 PMID:39145924 Surgical Staff: Mark Sywak, Alexander Papachristos, Stanley Sidhu, Anthony Glover; Leo Pang (Otolaryngology Head and Neck) Lian et al. 2024 “Endocrine surgery fellowship is necessary for competent endocrine surgical practice: perspectives from Australia and New Zealand.” ANZ J Surg 95: 66-71 PMID:39411952 Surgical Staff: Mark Sywak, Alexander Papachristos, Anthony Glover Metman et al. 2024 “MET-receptor targeted fluorescent imaging and spectroscopy to detect multifocal papillary thyroid cancer.” Eur J Nucl Med Mol Imaging 51: 2384-2394 PMID:38017325 Surgical Staff: Mark Sywak Nicholls et al. 2024 “Risk of malignancy in radiologically and cytologically discordant thyroid nodules, based on Thyroid Imaging, Reporting and Data System (TI-RADS) and Bethesda classifications.” BJS Open 8: zrad117 PMID:38242572 Surgical Staff: Alexander Papachristos, Anthony Glover, Mark Sywak, Stanley Sidhu, Ahmad Aniss Novis et al. 2024 “Oncogenic mutations in the TP53 and PI-3 kinase/AKT pathway are independent predictors of survival for advanced thyroid cancer: Analysis from the Molecular Screening and Therapeutics (MoST) program.” Surgery 177: 108858 PMID:39424488 Surgical Staff: Anthony Glover
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Papachristos et al. 2024 “Near-Peer Coaching to Enhance Operative Learning: An Educational Innovation for Surgical Training.” Ann Surg Open 5: e471 PMID:39310361 Surgical Staff: Alexander Papachristos Papachristos et al. 2024 “Open Adrenalectomy. In Illustrative Handbook of General Surgery.” Springer Nature Switzerland 56-68. Surgical Staff: Alexander Papachristos, Stanley Sidhu Papachristos et al. 2024 “Medullary Thyroid Cancer: Molecular Drivers and Immune Cellular Milieu of the Tumour Microenvironment-Implications for Systemic Treatment.” Cancers (Basel) 16: 2296 PMID:39001359 Surgical Staff: Alexander Papachristos, Stanley Sidhu Parente et al. 2024 “Robotic and Laparoscopic Adrenalectomy for Pheochromocytoma: An International Multicenter Study.” Eur Urol Focus 0: 00168-8 PMID:39278764 Surgical Staff: Mark Sywak, Alexander Papachristos Pasch et al. 2024 “Patience is key for the surgeon in the management of a large haemorrhagic phaeochromocytoma with cardiomyopathy.” ANZ J Surg 94: 2081-2083 PMID:39350501 Surgical Staff: Mark Sywak, Daniel Nguyen (Vascular), Jaswinder Samra (Upper GI) Schaap et al. 2024 “ASO Visual Abstract: Predictors of Bilateral Disease in Low-Risk Papillary Thyroid Cancer- Histopathological Insights and Preoperative Ultrasonography.” Ann Surg Oncol : PMID:39699614 Surgical Staff: Alexander Papachristos, Stanley Sidhu, Mark Sywak, Ahmad Aniss Serrao-Brown et al. 2024 “Intra-thoracic thyroid rests: an updated classification and case series.” ANZ J Surg 95: 72-76 PMID:39665507 Surgical Staff: Alexander Papachristos, Mark Sywak, Stanley Sidhu Serrao-Brown et al. 2024 “Outcomes of thyroidectomy in symptomatic, euthyroid Hashimoto's patients: a case control study.” ANZ J Surg 94: 1800-1805 PMID:39011996 Surgical Staff: Alexander Papachristos, Mark Sywak, Stanley Sidhu Tong et al. 2024 “Australian males and females have similar rates of presentation for symptomatic and advanced thyroid cancer: Retrospective analysis of the Australian New Zealand Thyroid Cancer Registry.” World J Surg 48: 2934-2940 PMID:39389930 Surgical Staff: Anthony Glover Verhoeff et al. 2024 “Outcomes for Patients with Obesity Undergoing Adrenalectomy for Pheochromocytoma: An International Multicenter Analysis.” Ann Surg Oncol 32: 1709-1720 PMID:39633172 Surgical Staff: Mark Sywak, Alexander Papachristos Wijewardene et al. 2024 “Reducing noise in radioactive iodine activity selection: the utility of an online clinical calculator.” Endocr Connect 13: e240299 PMID:39283868 Surgical Staff: Anthony Glover, Mark Sywak, Stanley Sidhu Xu et al. 2024 “Association of the Genomic Profile of Medullary Thyroid Carcinoma with Tumor Characteristics and Clinical Outcomes in an International Multicenter Study.” Thyroid 34: 167-176 PMID:37842841 Surgical Staff: Anthony Glover, Alexander Papachristos, Stanley Sidhu, Mark Sywak Yang et al. 2024 “Lymph node yield independently predicts local recurrence in papillary thyroid cancer.” World J Surg 49: 131-137 PMID:39532701 Surgical Staff: Alexander Papachristos, Mark Sywak, Stanley Sidhu, Ahmad Aniss Yang et al. 2024 “Geographic disparities in thyroid cancer staging at presentation: Insights from an Australian context.” World J Surg 48: 1440-1447 PMID:38733313 Surgical Staff: Anthony Glover Zeng et al. 2024 “The genomic and evolutionary landscapes of anaplastic thyroid carcinoma.” Cell Rep 43: 113826 PMID:38412093 Surgical Staff: Stanley Sidhu, Mark Sywak
2023
Birtwistle et al. 2023 “Minimally invasive adrenalectomy: a cohort study of surgical approach and outcomes.” ANZ J Surg 93: 2222-2228 PMID:37132079 Surgical Staff: Anthony Glover, Stanley Sidhu, Alexander Papachristos, Mark Sywak, Ahmad Aniss Chou et al. 2023 “A Detailed Histologic and Molecular Assessment of the Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma.” Mod Pathol 36: 100329 PMID:37716505 Surgical Staff: Stanley Sidhu, Mark Sywak, Anthony Glover, Ahmad Aniss Crayton et al. 2023 “Diffuse sclerosing variant papillary thyroid carcinoma has worse survival than classic papillary thyroid carcinoma: a meta-analysis.” Endocr Relat Cancer 30: e220348 PMID:36952650 Surgical Staff: Anthony Glover Kesby et al. 2023 “Natural History and Predictive Factors of Outcome in Medullary Thyroid Microcarcinoma.” J Clin Endocrinol Metab 108: 2626-2634 PMID:36964913 Surgical Staff: Alexander Papachristos, Mark Sywak, Stanley Sidhu, Anthony Glover Kesby et al. 2023 “Natural History and Predictive Factors of Outcome in Medullary Thyroid Microcarcinoma.” J Clin Endocrinol Metab 10 :2626-2634 PMID: 36964913 Surgical Staff: Alexander Papachristos, Mark Sywak, Stanley Sidhu Kesby et al. 2023 “Response to Letter to the Editor From Devgan and Mayilvaganan: "Natural History and Predictive Factors of Outcome in Medullary Thyroid Microcarcinoma".” J Clin Endocrinol Metab 109: e437 PMID:37379017 Surgical Staff: Alexander Papachristos, Mark Sywak, Stanley Sidhu, Anthony Glover Kumar et al. 2023 “Massive Biochemically Silent Pheochromocytoma Masquerading as Nonfunctioning Adrenocortical Cancer.” JCEM Case Rep 1: luad061 PMID:37908587 Surgical Staff: Anthony Glover
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Leong et al. 2023 “The Prognostic Impact of Extent of Vascular Invasion in Follicular Thyroid Carcinoma.” World J Surg 47: 412-420 PMID:36031639 Surgical Staff: Anthony Glover, Mark Sywak, Stanley Sidhu Lian et al. 2023 “A Prospective Study of Electromyographic Amplitude Changes During Intraoperative Neural Monitoring for Open Thyroidectomy.” World J Surg 47: 1971-1977 PMID:37005926 Surgical Staff: Mark Sywak Mechera et al. 2023 “A Nod to the Nodes: An Overview of the Role of Central Neck Dissection in the Management of Papillary Thyroid Carcinoma.” Surg Oncol Clin N Am 32: 383-398 PMID:36925192 Surgical Staff: Stanley Sidhu, Mark Sywak Nadeem et al. 2023 “Ki67 proliferation index in medullary thyroid carcinoma: A comparative study of multiple counting methods and validation of image analysis and deep learning platforms.” Histopathology 83: 981-988 PMID:37706239 Surgical Staff: Stanley Sidhu Nickel et al. 2023 “Putting Patients, Not Clinicians, at the Center of Care to Improve Management of Low-risk Thyroid Cancer.” JAMA Otolaryngol Head Neck Surg 149: 459-461 PMID:36951868 Surgical Staff: Anthony Glover Papachristos et al. 2023 “Management of Medullary Thyroid Cancer: Patterns of Recurrence and Outcomes of Reoperative Surgery.” Oncologist 28: 1064-1071 PMID:37632760 Surgical Staff: Alexander Papachristos, Stanley Sidhu, Anthony Glover, Mark Sywak, Ahmad Aniss Papachristos et al. 2023 “Scar-less thyroidectomy: an evolving role in the surgical armamentarium.” ANZ J Surg 93: 4 50-451 PMID:36939099 Surgical Staff: Alexander Papachristos, Stanley Sidhu Papachristos et al. 2023 “Beware the recurrent 'benign' multinodular goitre.” ANZ J Surg 93: 907-910 PMID:36852905 Surgical Staff: Alexander Papachristos, Stanley Sidhu Turchini et al. 2023 “A Critical Assessment of Diagnostic Criteria for the Tall Cell Subtype of Papillary Thyroid Carcinoma- How Much? How Tall? And When Is It Relevant?” Endocr Pathol 34: 461-470 PMID:37864666 Surgical Staff: Anthony Glover, Mark Sywak, Stanley Sidhu Turchini et al. 2023 “The Presence of Typical "BRAFV600E-Like" Atypia in Papillary Thyroid Carcinoma is Highly Specific for the Presence of the BRAFV600E Mutation.” Endocr Pathol 34: 112-118 PMID:36709221 Surgical Staff: Anthony Glover, Mark Sywak, Stanley Sidhu Wang et al. 2023 “Genotype-Phenotype Correlations and Clinical Outcomes in 155 Cases of Pheochromocytoma and Paraganglioma.” World J Surg 47: 690-698 PMID:36550325 Surgical Staff: Alexander Papachristos, Anthony Glover, Mark Sywak, Stanley Sidhu, Ahmad Aniss White et al. 2023 “Development of a novel clinical support tool for active surveillance of low risk papillary thyroid cancer.” Front Endocrinol (Lausanne) 14: 1160249 PMID:37766695 Surgical Staff: Anthony Glover Worrall et al. 2023 “Lobectomy and completion thyroidectomy rates increase after the 2015 American Thyroid Association Differentiated Thyroid Cancer Guidelines update.” Endocr Oncol 3: e220095 PMID:37434647 Surgical Staff: Alexander Papachristos, Anthony Glover, Stanley Sidhu, Mark Sywak, Ahmad Aniss
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