RNSH DoSA Research Activity Report 2023 - 2024

• An intensive approach to vasospasm in patients with aneurysmal subarachnoid haemorrhage • Determining feasibility of using the Brief-COPE assessment tool to identify those at risk of developing Post Intensive Care Syndrome - Family (PICS-F) analgesia in burns - short term implications and association with chronic pain • An evaluation of the factors associated with duration of external ventricular drains in patients with aneurysmal subarachnoid haemorrhage • External validation of the Subarachnoid Haemorrhage Outcome Tool (SAHOT)

PUBLICATIONS

2024

Abdul-Aziz et al. 2024 “ Prolonged vs Intermittent Infusions of β -Lactam Antibiotics in Adults With Sepsis or Septic Shock: A Systematic Review and Meta-Analysis” JAMA 332: 638-648 PMID:38864162 ICU Staff: Anthony Delaney, Naomi Hammond Adigbli et al. 2024 “Managing blood glucose in the intensive care unit” Intensive Care Med 51: 442-443 PMID:39714614 ICU Staff: Simon Finfer, Naomi Hammond, Derek Adigbli Adigbli et al. 2024 “A Patient-Level Meta-Analysis of Intensive Glucose Control in Critically Ill Adults” NEJM Evid 3: EVIDoa2400082 PMID:38864749 ICU Staff: Simon Finfer, Anthony Delaney, Naomi Hammond, Derek Adigbli, Ruan Vlok, Richard Chator, Sajeev Mahendran Adigbli et al. 2024 “Early persistent Lymphopenia and risk of death in critically ill patients with and without sepsis” Shock 61: 197-203 PMID:38151771 ICU Staff: Simon Finfer, Naomi Hammond, Derek Adigbli Anderson et al. 2024 “What to Measure in Aneurysmal Subarachnoid Haemorrhage Research-An International Delphi Survey.” Transl Stroke Res 16: 49-78 PMID:38997598 ICU Staff: Chris Anderson, Anthony Delaney Anstey et al. 2024 “How often are infusion sets for central venous catheters changed in Australian and New Zealand Intensive Care Units? A point prevalence survey.” Aust Crit Care 3 :495-498 PMID: 37385895 ICU Staff: Naomi Hammond Arabi et al. 2024 “European Society of Intensive Care Medicine clinical practice guideline on fluid therapy in adult critically ill patients. Part 1: the choice of resuscitation fluids” Intensive Care Med 50: 813-831 PMID:38771364 ICU Staff: Naomi Hammond Battaglini et al. 2024 “Stroke in critically ill patients with respiratory failure due to COVID-19: Disparities between low- middle and high-income countries.” Heart Lung 68: 131-144 PMID:38968643 ICU Staff: Elizabeth Yarad, Pierre Janin Betteridge et al. 2024 “Blood Pressure Management Goals in Critically Ill Aneurysmal Subarachnoid Hemorrhage Patients in Australia and New Zealand” J Neurosurg Anesthesiol 36: 237-243 PMID:37442781 ICU Staff: Anthony Delaney, Emily Fitzgerald Ceric et al. 2024 “Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis” EClinicalMedicine 71: 102569 PMID:38572080 ICU Staff: Anthony Delaney Chadwick et al. 2024 “The incidence of ventriculostomy-related infections as diagnosed by 16S rRNA polymerase chain reaction: A prospective observational study” J Clin Neurosci 126: 57-62 PMID:38843672 ICU Staff: Anthony Delaney, Naomi Hammond, Pierre Janin, Oliver Flower, Frances Bass, Kelly Harbour Chaudhuri et al. 2024 “Executive Summary: Guidelines on Use of Corticosteroids in Critically Ill Patients With Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia Focused Update 2024” Crit Care Med 52: 833-836 PMID:38240490 ICU Staff: Naomi Hammond Chaudhuri et al. 2024 “2024 Focused Update: Guidelines on Use of Corticosteroids in Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia” Crit Care Med 52: e219-e233 PMID:38240492 ICU Staff: Naomi Hammond Cook et al. 2024 “Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation” N Engl J Med 391: 9-20 PMID:38875111 ICU Staff: Simon Finfer, Naomi Hammond Dennis et al. 2024 “Protocol implementation during the COVID-19 pandemic: experiences from a randomized trial of stress ulcer prophylaxis” BMC Med Res Methodol 24: 109 PMID:38704520 ICU Staff: Simon Finfer, Naomi Hammond Donaldson et al. 2024 “Quantifying the Impact of Alternative Definitions of Sepsis-Associated Acute Kidney Injury on its Incidence and Outcomes: A Systematic Review and Meta-Analysis” Crit Care Med 52: 1264-1274 PMID:38557802 ICU Staff: Anthony Delaney, Naomi Hammond, Lachlan Donaldson, Ruan Vlok, Gabbi McDonald, Morgan Burrows, Ken Sakkurai

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