RNSH DoSA Research Activity Report 2023 - 2024

NEUROINTERVENTION UNIT Head of Department: Jonathon Parkinson

DEPARTMENTAL RESEARCH RESOURCES

CLINICAL DATABASES TO SUPPORT OUTCOMES RESEARCH • Interventional NeuroRadiology (INR) Workload Database • Endovascular Clot Retrieval Database LINKS TO TRANSLATIONAL RESEARCH PARTNERS OR UNIVERSITY DEPARTMENTS • Boston University • Royal Melbourne Hospital

CURRENT RESEARCH ACTIVITY

• Intraarterial TNK in medium vessel occlusion stroke (MOSS – PI) • Pharmacogenomics in INR. Pharmacogenomics guided strategy for antiplatelet selection in Neurointervention • Direct endovascular clot retrieval (compared to bridging intravenous thrombolysis with endovascular clot retrieval) clinical trial (DIRECT-SAFE) • The Monitoring Of Stroke Endovascular Services (MOSES) study - observational study • Co PI Extend DNASE • Randomised controlled trial of endovascular versus standard medical therapy for stroke with occlusion of posterior cerebral artery (FRONTIER-AP Vision)

PUBLICATIONS

2024

Diprose et al. 2024 “Ophthalmic artery stenosis on three-dimensional rotational angiography: Interrater agreement, prevalence, and risk factors.” Interv Neuroradiol : 15910199241233000 PMID:38387875 Surgical Staff: Alice Ma, Brendan Steinfort Drumm et al. 2024 “Basilar artery occlusion management: An international survey of middle versus high-income countries.” Interv Neuroradiol 30: 702-711 PMID:36514286 Surgical Staff: Alice Ma Mulcahy et al. 2024 “Staged Common and External Carotid Artery Stenting Followed by Superficial Temporal Artery to Middle Cerebral Artery Bypass.” J Neurol Surg a Cent Eur Neurosurg 85: 412-416 PMID:35453160 Surgical Staff: Brendan Steinfort, Nazih Assaad (Neurosurgery) Peacock et al. 2024 “Basilar artery occlusion management: An international survey of gender influence on management.” Interv Neuroradiol : 15910199241265500 PMID:39140366 Surgical Staff: Alice Ma Sun et al. 2024 “Unsuccessful Recanalization versus Medical Management of Patients with Large Ischemic Core : Analysis of the ANGEL-ASPECT Randomized Trial.” Clin Neuroradiol 34: 441-450 PMID:38319347 Surgical Staff: Alice Ma

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