LINKS TO TRANSLATIONAL RESEARCH PARTNERS OR UNIVERSITY DEPARTMENTS • Speciality of Surgery, University of Sydney • The Bowel Cancer and Biomarker Laboratory, Kolling Institute • All Upper GI tumours resected at Royal North Shore Hospital and North Shore Private Hospital including sera (2001-2020) – stored in the Kolling Institute tumour bio-bank • Colorectal Cancer, Kolling Institute o ASERNIP-S, Royal Australasian College of Surgeons o University of Adelaide • Wexner Medical Centre, The Ohio State University, United States of America • University of Otago, New Zealand
CURRENT RESEARCH ACTIVITY
OESOPHAGOGASTRIC CANCER • Outcomes following benign foregut surgery including quality of life assessment • Outcomes following oesophago-gastric cancer surgery • Characterising the laparoscopic bypass learning curve in an Australian context (cohort study) • The impact of age on the management and outcome of patients undergoing resection for oesophageal and gastric cancer (cohort study) • Cohort study on whether neoadjuvant chemoradiotherapy increases post-operative complications following oesophagectomy • Incidence and hospital health care costs of cervical anastomotic leaks in oesophagectomy patients (cohort study) • Long term quality of life and nutritional outcomes study following oesophagectomy • Cohort study into whether surgical approach (Ivor Lewis vs. Three stage) impact post-operative complications following an oesophagectomy HEPATOBILIARY SURGERY AND HERNIA • Systematic review of predictive biomarkers in cholangiocarcinoma • Economic cost of treatment of colorectal liver metastases • Systematic review of the use of a Hepatobiliary IminoDiacetic Acid scan in patients with acalculous biliary symptoms • A validation of the National Surgical Quality Improvement Program surgical risk score after liver resection: a single institution analysis of 20 years of consecutive hepatectomies (cohort study) • Cholangiocarcinoma (Klatskin) patterns of presentation, treatment, survival and disease recurrence over a 20-year period in a large tertiary Australian hospital • Variations in clinical practice and outcome of hernia surgery (recurrent inguinal hernias, quality of life after ventral hernia repair, groin pain) • Serological genomic and proteomic markers of early recurrence of Colorectal Liver Metastases (CRLM) • AI for improving surgical education and outcomes • Breaking barriers to timely discharge: a mixed-methods study on delayed hospital discharge in gastrointestinal surgery patients PANCREATIC SURGERY • Review of pancreatitis related to percutaneous transhepatic cholangiography at the Northern Campus • Benchmarking in pancreatic surgery to compare the Northern Campus outcomes against published studies • Management of acute cholecystitis in patients with biliary stenting during neoadjuvant therapy in patients with pancreatic adenocarcinoma (cohort study) • Serum biomarkers in pancreatic cancer (several cohort studies) • Gene expression analysis of pancreatic ductal adenocarcinomas (PDAC) to identify surrogate markers for molecular phenotypes of PDAC • Urinary metabolomic biomarkers for PDAC • Stage IV PDAC resections – study of prognosis and survival
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