RNSH DoSA Research Activity Report 2023 - 2024

Clinical Research • The relationship between clinical grade of perioperative anaphylaxis and serum tryptase level • Retrospective review of prior exposure to sugammadex during anaesthesia in patients who have confirmed sugammadex anaphylaxis • A five-year experience of paediatric perioperative anaphylaxis at a tertiary level mixed paediatric and adult anaesthetic allergy service in Sydney, Australia • Cefazolin Anaphylaxis: evaluation of persistence of sensitization up to 10 years after the sentinel event • Paediatric perioperative hypersensitivity: comparison of two tryptase formulae to support a diagnosis of mast cell activation • Peripherally Inserted Central Catheter (PICC) line service utilisation study • Code crimson activation and outcomes study • Acute rib fracture management study • Linking data between perioperative drug allergy services in the ANZAAG network • Development of cost-efficient and effective intravenous drug challenge protocols in perioperative drug allergy • Assessment of maximal non-irritant concentrations of cisatracurium in intradermal drug allergy testing • Evaluation of clinical scoring tools to assist diagnosis and triage in perioperative allergy • Skin testing - in vitro testing and drug provocation testing for diagnosis and management of drug allergy

PUBLICATIONS

20242

Arenas-Castro et al. 2024 “Academic publishing requires linguistically inclusive policies.” Proc Biol Sci 291: 20232840 PMID:38471557 Anaesthesia Staff: Supriya Chowdhury Armstrong et al. 2024 “Management of Patients With Refractory Reflux-Like Symptoms Despite Proton Pump Inhibitor Therapy: Evidence-Based Consensus Statements.” Aliment Pharmacol Ther 61: 636-650 PMID:39740235 Anaesthesia Staff: Paul Sinclair Ashton-James et al. 2024 “Efficacy of an mHealth intervention to support pain self-management and improve analgesia in patients with rib fractures: protocol for a randomised controlled trial.” BMJ Open 14: e086202 PMID:39510779 Anaesthesia Staff: Matthew Doane, Paul Glare, Damien Finniss Chlap et al. 2024 “Uncertainty estimation using a 3D probabilistic U-Net for segmentation with small radiotherapy clinical trial datasets.” Comput Med Imaging Graph 116: 102403 PMID:38878632 Anaesthesia Staff: Jennifer Tan Chuan et al. 2024 “Using Virtual Reality to teach ultrasound-guided needling skills for regional anaesthesia: A randomised controlled trial.” J Clin Anesth 97: 111535 PMID:38889487 Anaesthesia Staff: Supriya Chowdhury Cook et al. 2024 “Modified Circuit for Left-Sided Heart Bypass in Thoracoabdominal Surgery.” Ann Thorac Surg Short Rep 2: 21-24 PMID:39790259 Anaesthesia Staff: Andy Wang, Bruce Adendorff Cornall et al. 2024 “Management of pain in cancer patients- lessons from practices during the COVID-19: a qualitative study of cancer care providers' perspectives.” BMC Health Serv Res 24: 232 PMID:38388905 Anaesthesia Staff: Paul Glare, Andy Wang Dionne et al. 2024 “Canadian Spine Society: 24th Annual Scientific Conference, Wednesday, February 28 - Saturday, March 2, Fairmont Chateau Whistler, Whistler, B.C., Canada.” Can J Surg 67: S17-S76 PMID:39537311 Anaesthesia Staff: Andrew Howard; Charles Fisher (Vascular) , Ragavan Manoharan (Neurosurgery) Elhage et al. 2024 “The effect of adductor canal block on outcomes of total knee arthroplasty: A single centre, historical cohort study.” J Orthop 65: 31-35 PMID:39801907 Anaesthesia Staff: Ben Olesnicky Ferreira et al. 2024 “How is postoperative pain after hip and knee replacement managed? An analysis of two large hospitals in Australia.” Perioper Med (Lond) 13: 49 PMID:38822448 Anaesthesia Staff: Paul Glare Gholamrezaei et al. 2024 “A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial.” Pain Rep 9: e1128 PMID:38352024 Anaesthesia Staff: Paul Glare Glare et al. 2024 “Chronic pain in cancer survivors improved after learning pain self-management techniques in an Australian pain clinic.” Pain Med 25: 578-580 PMID:38775651 Anaesthesia Staff: Paul Glare

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