Helix

HELIX SPECIALTY DIAGNOSTICS

Keeping Communities Healthy & Giving Back LCMS TESTING

ABOUT Helix Specialty Diagnostics Quantitative testing

Creating a Business that Serves the Community

CONTENTS TABLE OF 06 08 10 About Percision Diagnostics Urine Drug Testing Our Leadership Team 18 20 Commitment to Quality Precision Integration

22 24 26

Our Core Values

12 14 16

Our Leadership Team Continued

Precision UpNEXT

NextGen Precision Testing

Pricing Transparency

Oral Fluid Testing

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H elix Specialty Laboratory is a minority owned CLIA certified clinical laboratory. Helix Specialty Laboratory was established in St. Louis, MO in 2019. Helix Specialty Laboratory offers toxicology testing services to a variety of industries, including physician offices, employers, government agencies, health clinics, pain management practitioners, and rehabilitation centers. Our accurate drug testing helps providers mitigate the risk of drug abuse while allowing their patients to continue on controlled medications. For urine drug screens, we perform a semi-quantitative 13-part comprehensive drug profile by enzyme immunoassay (EIA) accompanied by a 3-part validity test on our state-of-the-art chemistry analyzer. In addition to the 13-part drug profile, we offer semi-quantitative buprenorphine screening. Helix Specialty Laboratory laboratory has the most advanced

LC/MS instrumentation for quantitative drug confirmations, Our drug confirmations expands beyond the 13-part comprehensive drug profile to identify and quantify the exact analyses present, verify medications, test for and quantify analyses not screened in EIA, and eliminate false positives and false negatives. We test for and monitor 55 different drug compounds and metabolites by LC/MS confirmation on urine specimen. HELIXSD.COM

ABOUT Helix Specialty Diagnostics

CLIA certified

314.455.2777

Keeping Communities Healthy & Giving Back Jessica Pfiffer: Owner of Helix Specialty Diagnostics

J essica Pfiffer is the owner and CEO of Helix Specialty Diagnostics, a clinical laboratory providing testing

delegates and directs agendas,

drives manages, communicates, tracks performance, and strategizes. And perhaps most importantly, she profitability, is the face of the company. “I'm a minority woman, an African American disabled veteran. But I like to focus on the fact that I'm originally from Los Angeles. I grew up when there was the crack epidemic, gang violence, high crime, police brutality—you name it, we had it. As a child, medical care was a privilege. In my household, you didn’t go to the doctor unless you were dying. In these communities, we self-diagnose

services and results. “Helix has been around since 2019. I purchased the lab from another owner earlier this year.” She shares what Helix is all about: “My organization provides one of the first steps in identifying health problems. Without accurate testing, you don't have a medical diagnosis. The first way to fix the problem is to understand that there is a problem.” What do her duties entail? “As CEO, I serve as senior management, and I'm a member of the board, so I'm responsible for the overall success and operation of the company.” She

“LIFE HAS BLESSED ME, SO IT’S MY DUTY AND OBLIGATION TO PAY IT FORWARD.”

and self-treat. We are underprivileged and underserved, and as humans, we're creatures of habit, products of our environment. My mother was a teen mom; I was a teen mom. I didn't receive a professional pregnancy test until I was in my second trimester, which shows the importance of testing and I want it to be there.” Jessica had a child at 16 but was determined to move forward. “I joined the military when I was 18, got my bachelor's degree, and by 24, I started my career in IT. I became a system engineer, got my graduate degree in IT management, and fast-tracked my way up to senior management at one of the world's top five defense contracting companies. Being successful in that career gave me the leverage today to be blessed with the resources to build a company that serves the community—that makes a difference. Healthcare is a necessity, but unfortunately, it's a privilege for many Americans. Life has blessed me, so it’s my duty and obligation to pay it forward.” The goal at Helix is to provide affordable testing with

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Keeping Communities Healthy

& Giving Back CONTINUED...

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a fast turnaround time and the same level of service typically offered to higher social classes. “At Helix, our main goal is to bridge that healthcare gap. We want to ensure that those underserved communities have access to the latest and most advanced tests in the market.” This includes three new-to-the-market tests in one: COVID, flu (A&B), and RSV, to fight the current triple demic. And she cares. “When we talk about building communities, we have to focus on the overall health of the community. Here at Helix, the tests we offer provide results. It’s important to know where you're at, to know where you're going.” Speaking of healthy communities, Helix also does its share for those in recovery. “We do drug tests—we work with many rehabilitation centers.” Helix tests not only for illicit drugs but also works with doctors to ensure patients taking prescribed medications are not abusing those drugs. Jessica’s ultimate goal? “I want to inspire young black and brown boys and girls through my story because you can't reach the people if you're not where they're at.”

H elix offers toxicology testing services to a variety of industries, including physician offices, employers, government agencies, health clinics, pain management practitioners, and rehabilitation centers. Our Services • Toxicology Confirmation • Toxicology Screening • CBD and Validity Testing • Molecular Diagnostics & Genetic Testing

• Women’s Health and STI Testing • Virology and Immunology Testing

CONTACT HELIX TODAY! 11829 DORSETT ROAD MARYLAND HEIGHTS, MO 63043 (O) 314.455.2777 EMAIL: INFO@HELIXSD.COM WEBSITE: HTTPS://WWW.HELIXSD.COM

LCMS TESTING

L CMS testing stands for Liquid Spectrometry testing. It is a highly sensitive analytical technique used for the identification and quantification of various compounds in a sample. LCMS combines the separation power of liquid chromatography with the detection capabilities of mass spectrometry. In LCMS testing, a sample is first Chromatography-Mass separated using liquid chromatography based on its chemical properties. The separated components are then introduced into a mass spectrometer where they are ionized and analyzed based on their mass-to-charge ratio. The resulting mass spectra provide information about the identity and quantity of the compounds present in the sample.

LCMS testing is widely used in various fields such as pharmaceuticals, forensics, environmental analysis, food and beverage testing, clinical diagnostics, and drug screening. It is particularly useful for detecting and quantifying trace amounts of substances, including drugs, metabolites, pesticides, environmental pollutants, and biomarkers. LCMS testing offers high sensitivity, selectivity, and accuracy, making it an essential tool in research, quality control, and clinical laboratories for identifying and measuring a wide range of compounds in complex samples.

CONTACT HELIX TODAY! 11829 DORSETT ROAD MARYLAND HEIGHTS, MO 63043 (O) 314.455.2777 EMAIL: INFO@HELIXSD.COM WEBSITE: HELIXSD.COM

THE STORY OF Sylvester Williams & H elix S pecialty D iagnostics

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Experience

FOUNDER & CEO

Sylvester Williams

A s a nation of immigrants, many of us come from the humblest of beginnings in search of our own particular American dream. The vast majority work hard to reach even modest success yet we still continue to painstakingly carve out our foundations for the next generation to follow. And then there are those few of us who achieve on a scale that creates a beaming beacon of shining light for all to see. Founder and CEO of Helix Laboratory, Sylvester Williams, would be a prime example of this light.

committed discipline, a realization that had been honed over the previous summer’s toil in his first factory job. Hard factory labor had also convinced the young man that he must take the wheel of his future if he were to go anywhere other than straight back to his factory’s timeclock. Yet HS football success would not immediately transfer to gridiron glory as the JCHS graduate would find himself entirely unrecruited by any major program and with very limited options for any collegiate football career and education at all. Yet here

As a child of working class parents

who toiled long and hard to improve their family’s opportunities, young Sylvester was a gifted athlete—with size, strength and speed to spare—who dreamed of an NFL career upon entering Jefferson City High School. The headstrong teenager was indeed dreaming big but also temporarily ignoring the lessons of his hard working parents until he stumbled into his first major hurdle—a sophomore suspension due to neglected academics. Yet this adolescent misstep led to his first crucial understanding in how to both pivot and realign his goals.

he found himself prepared to bootstrap his way forward. Determined to make an athletic impact on his own, young Mr. Williams got into his first car and drove himself to Kansas and Coffeeville Community College to reboot his football career. After tremendous Juco success in his freshman year however, the defensive lineman found himself, again, unrecruited by any D-1 programs. And so it was back to his car for a long drive to the renowned University of North Carolina where he would bet big on himself and tryout as a true

and entirely unheralded “walk-on”.

His HS football coach spotted his obvious potential and encouraged him to switch sports and give the hard lessons of the gridiron a go. The junior year Mr. Williams heeded that call then quickly realized that both his athletic and academic work ethic would require the much needed addition of

After quickly establishing himself as an invaluable force on the UNC defense, the rapidly maturing Mr. Williams continued to redouble both his academic

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“ Instead of simply a group of talented “employees” working on their own goals and agendas, we always strive to create a true family and put in the work every day, together. Because I believe that inclusive work wins together.”

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and athletic efforts, completing his degree in Communications and going on to become a 2013, 1st round draft pick of the Denver Broncos. What followed was one definition of hard work paying off, and the All-American dream come true. After 2 years of stellar play— and some tough NFL playoff seasoning—Mr. Williams and his Broncos team would go on to win 2016’s Super Bowl 50! Years of NFL success would follow before Mr. Williams returned to his beloved Broncos to finally call it a career. And then it was time to pivot and realign again. H ELIX L ABORATORY IS C REATED TO S ERVE While many former NFL players elect to either cash in on their fame or rest on their hard-earned laurels Mr. Williams chose instead

to enter the private sector with service to his community in mind. After honing his business skills in both trucking and real estate, in 2019 he founded Helix Laboratory as the St. Louis area’s first minority-owned CLIA certified clinical laboratory. The primary goal was simple-- to bring advanced diagnostic testing to underserved communities—and, of course, the need was evident. Although Helix’s services are comprehensive, the compelling need to tackle the complexities of a worldwide pandemic became the priority, and serving a community filled with understandable apprehension was the immediate challenge. But here Mr. Williams applied some of the most successful lessons he’d learned in the NFL to his new Helix team.

In recent conversation he shared- “You know in my 2013 rookie year we had a very talented team…and then we got blown out in the 1st round of the playoffs. In 2015 we had a very talented team also, but now we’d become a family. With our Helix team it’s the same. Instead of simply a group of talented “employees” working on their own goals and agendas, we always strive to create a true family and put in the work every day, together. Because I believe that inclusive work wins together.” As CEO, Mr. Williams strongly believes that this idea of family as applied to his community is what sets both Helix’s services and its outreach apart. Driving a One-of-One service forward into the future is something he knows is a constant challenge but it’s a challenge that he understands will build a stronger, healthier tomorrow for all of us.

Quantitative testing

Q uantitative testing, also known as quantitative analysis or assay, is a method used to determine the concentration or amount of a specific substance or analyte in a sample. It involves the measurement of the quantity of a target analyte present, often expressed in terms of mass, volume, concentration, or percentage. CONTINUE READING>>>

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4. Gravimetry: Gravimetric analysis involves the determination of the analyte's mass by measuring a change in mass before and after a chemical reaction or physical process. 5. Electrochemical methods: Electrochemical techniques, like voltammetry or potentiometry, use electrical measurements to determine the concentration of an analyte based on its electrochemical behavior. Quantitative testing plays a crucial role in various scientific and analytical fields, including pharmaceuticals, environmental analysis, clinical diagnostics, food and beverage industry, and quality control. Accurate quantification of analytes is essential for assessing product quality, ensuring safety, monitoring processes, and evaluating compliance with regulatory standards.

Quantitative testing can be performed using various techniques, depending on the nature of the analyte and the requirements of the analysis. Some common quantitative method measures the absorbance or transmission of light by a sample at a specific wavelength, allowing for the determination of analyte concentration based on a calibration curve. 2. Titration: In titration, a solution of known concentration (titrant) is added to the sample until a chemical reaction reaches completion. The volume of titrant required to reach the endpoint is used to calculate the analyte concentration. 3. Chromatography: Chromatographic testing methods include: 1. Spectrophotometry: This techniques, such as high-performance liquid chromatography (HPLC) or gas chromatography (GC), can be utilized for quantitative analysis by measuring the peak area or peak height of the analyte in comparison to calibration standards.

HELIXSD.COM

Creating a Business that Serves the Community B ecause proper professional healthcare is always vital for all.

PRESIDENT

Jason Griffin

C hallenges are a major reality of our human condition. A great deal of our humanity shines through when we’re tested and it’s safe to say that—as fellow human beings sharing our world together—we’ve all been tested in these most recent years. The very best of us have met our health challenges head on and worked hard to help solve our health crisis. As President of Helix Laboratory, Jason Griffin has met that challenge and lead his team to the solutions we

all need to move forward. Mr. Griffin began his journey in 2004 at the University of Arkansas at Pine Bluff when he graduated with his degree in Business Management and immediately got to work in the home healthcare industry where he enjoyed great individual success for over eight years. It was then that family called and requested his professional experience and expertise in getting their burgeoning trucking company off the ground and running. Their soon booming trucking concern eventually segued into establishing a real estate business which focused on housing for lower income families within their community. As a growing family business, Mr. Griffin then seized an opportunity to reenter the health space in 2019 when he and brother-in-law Sylvester Williams created Helix Laboratory to both fill an evident community need and to provide the highest level service to underserved communities and families most in need of that very specific service.

C oaching is a leadership position that requires you to first develop a plan. -Jason Griffin

O ftentimes our community doesn't have many people who look like them, offering this type of absolutely vital service where it's most needed.

Creating a Business

that Serves the Community CONTINUED...

Within the greater St. Louis area, Helix Laboratory immediately set their mark on their primary mission and everyday goal- “Bringing advanced diagnostic testing to underserved communities in need.” Of course when the pandemic hit the world hard, Mr. Griffin and Helix Laboratory were perfectly poised and positioned to tackle the unique challenges we were all suddenly suffering through. As a former Track and Field Head Coach at the Collegiate School of Medicine and Bioscience, now Mr. Griffin is even more firmly convinced of sharing the vital lessons in leadership he both taught and learned during his coaching tenure with his new Helix Laboratory team. In recent conversation, President Griffin shared his thoughts- “Coaching is a leadership position that requires you to first develop a plan, then put that plan into action with your team fully onboard, and to always be ready to create that team mentality within the most diverse setting.” Given Helix Laboratory’s professional mission and commitment, Mr. Griffin eagerly shoulders the great responsibility of providing service to many of St. Louis’ most underserved communities and also fully understands that the diversity of his Helix team is itself of service to many.

Moving forward, President Griffin sees both national and international expansion of Helix Laboratory’s services as the next logical step yet also keeps a steady course on their professional priorities- · Remain close to Helix’s team/ family/staff

· Remain family-oriented in foundation and action

· Continue to reach our goals

· Always keep our eyes on improving our service.

Our constant human reality is that challenges will always present themselves but with Mr. Griffin and Helix Laboratory, every community can safely trust that we’re ready to meet those challenges with commitment and confidence.

Our Services

• Toxicology Confirmation • Toxicology Screening • CBD and Validity Testing • Molecular Diagnostics & Genetic Testing • Women’s Health and STI Testing • Virology and Immunology Testing

HELIXSD.COM 314.455.2777

11829 Dorsett Road, Maryland Heights, MO

QUALITATIVE TESTING

Q ualitative testing is a method used to determine the presence or absence of a particular substance or analyte in a sample without quantifying its concentration. Instead of providing numerical values, qualitative testing focuses on providing a yes/no or positive/negative result. Qualitative testing can be performed using different techniques, depending on the nature of the analyte and the requirements of the analysis. Some common qualitative testing methods include: 1. COLORIMETRIC TESTS: These tests rely on color changes to indicate the presence or absence of a specific analyte. Reagents or indicators are added to the sample, and the resulting color change or formation of a precipitate is observed. HELIXSD.COM

2. IMMUNOASSAYS: Immunoassays use specific antibodies or antigens to detect the presence of a target analyte. Various formats, such as enzyme-linked immunosorbent assays (ELISA) or lateral flow assays, are utilized in qualitative immunoassays. 3. SPOT TESTS: Spot tests involve the application of a specific reagent directly to the sample. The appearance of a characteristic color, precipitation, or other observable changes indicates the presence of the analyte. 4. ODOR OR TASTE TESTS: Some qualitative tests rely on sensory evaluation, such as identifying specific odors or tastes associated with certain substances.

CONTACT HELIX TODAY! 11829 DORSETT ROAD MARYLAND HEIGHTS, MO 63043 314.455.2777 INFO@HELIXSD.COM Qualitative testing is widely used in fields such as clinical diagnostics, environmental monitoring, drug screening, forensic analysis, and food safety. It provides valuable information regarding the presence or absence of target substances, allowing for rapid screening, initial identification, and decision- making processes. However, it should be noted that qualitative tests do not provide precise quantitative measurements of analyte concentration, which may require additional quantitative testing methods.

CONTACT HELIX TODAY! 11829 DORSETT ROAD MARYLAND HEIGHTS, MO 63043 314.455.2777

INFO@HELIXSD.COM

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