FACULTY OF MEDICAL SCIENCES
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Sick Kids-Caribbean Initiative (SCI) In 2013, the SCI established a hospital-based paediatric cancer registry in the Depart- ment of Pathology, which registers all cases of childhood cancer diagnosed and/or treated at the University Hospital of the West Indies. Case registration continued in the 2022/2023 academic year, and the data collected will be used for upcoming research publications. Fox Chase Cancer Center (FCCC), Philadelphia, USA The department continued its collaboration with the FCCC on two projects: “The Jamaica Sherlock Lung Cancer Study: Tracing lung cancer mutational processes in never smokers” and “Impact of African ancestry on DNA polymerase beta (POLB) protein expression and survival in patients with oral cavity and laryngeal squamous cell carcinoma”. Molecular Oncology Research Group (Department of Pathology and the Caribbean Institute for Health Research – CAIHR) This group is investigating the molecular landscape of the common cancers in our population – a population comprised predominantly of individuals of African ancestry. Departments of Pathology and Surgery, UWI, Mona and Department of Urology, Johns Hopkins University, Baltimore, Maryland, USA – Research on Prostate Cancer This is a newly established research group which will be investigating the X285K variant of the HOXB13 gene, and other genetic alterations, in prostate cancers in Jamaican men.
RESEARCH PUBLISHED DURING THE 2022/2023 ACADEMIC YEAR
Books and Monographs • Browne-Farmer C, Baxter JB, Alexis C, Allen U, Beeput S, Bodkyn C, George C, Gibson D, Gibson T , Leandre-Broome V, Mclean-Salmon S, Reece-Mills M, Sin Quee C, Gupta S. “Reflections on the SickKids-Caribbean Initiative: Local Oncology Databases Development” . Toronto: Hospital for Sick Children; 2023. Refereed Journal Articles • Clarke S, Chin SN , Dodds L, George SHL, Badal S. “Racial disparities in breast cancer preclinical and clinical models”. Breast cancer research: BCR 2022; 24 (1): 56. https://doi.org/10.1186/s13058-022-01551-x
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