Hyperbaric Oxygen Therapy (HBOT)

At Longevity Medical Institute, we believe true healing begins at the cellular level. Hyperbaric Oxygen Therapy (HBOT) is a foundational tool in regenerative and functional medicine.

Hyperbaric Oxygen Therapy (HBOT) The Restorative Power of Pressurized Oxygen — Now Available in Comfort

At Longevity Medical Institute, we believe true healing begins at the cellular level. Hyperbaric Oxygen Therapy (HBOT) is a foundational tool in regenerative and functional medicine—non-invasive, deeply restorative, and backed by decades of clinical research. We offer three (3) state-of-the-art, seated hyperbaric chambers, designed for comfort, calm, and accessibility. Unlike traditional tube-style chambers, ours let you sit upright or recline, read, relax, or meditate while receiving over 96% oxygen in a pressurized environment of up to 2.0 ATA (atmospheres absolute) - delivering profound benefits in just 60–90 minutes. What Is HBOT — and Why Is It So Different from Just Breathing Oxygen? In everyday life, we breathe 21% oxygen at sea-level pressure (1.0 ATA). Under these conditions: Oxygen is primarily carried by hemoglobin inside your red blood cells. Once hemoglobin is saturated (usually near 100%), adding more oxygen doesn't significantly increase delivery to tissues. Only a tiny fraction of oxygen is dissolved directly into the plasma- limiting its reach in inflamed, damaged, or poorly perfused tissues. HBOT changes everything. By increasing both the concentration of oxygen (96%+) and the ambient pressure, oxygen dissolves not just into red blood cells—but also into your plasma, cerebrospinal fluid, lymphatic fluid, and interstitial spaces. This allows oxygen to bypass circulatory bottlenecks and flood even the most hypoxic or inflamed tissues with up to 20 times more available oxygen than normal breathing.

A Simple Analogy: Sparkling Water

Imagine you’re turning still water into sparkling water.

You do this by forcing carbon dioxide into water under pressure. The gas doesn’t just float around—it dissolves into the liquid.

HBOT works on the same principle. By increasing pressure in a sealed chamber, oxygen is forced into your body’s fluids—not just carried by red blood cells, but dissolved directly into plasma, enabling delivery to compromised tissues that need it most.

The Science Behind HBOT: How It Works

HBOT is effective because of two fundamental gas laws:

01. Henry’s Law

The amount of gas that dissolves in a liquid is proportional to the pressure of that gas above the liquid. In HBOT, increased pressure causes more oxygen to dissolve into your bloodstream and tissues.

02. Boyle’s Law

At constant temperature, pressure and gas volume are inversely related. This principle explains how HBOT can reduce gas bubbles (like in decompression sickness) and how tissue oxygenation becomes more efficient under pressure.

Clinical Evidence

Studies have shown that HBOT can:

Increase stem cell mobilization (up to 8x baseline levels) Enhance angiogenesis (growth of new blood vessels) Improve neuroplasticity and brain repair Modulate chronic inflammation and oxidative stress Support mitochondrial function and ATP production Aid in tissue regeneration and wound healing

It is FDA-approved for 14 conditions and used off-label for over 120 indications including neurological, orthopedic, cardiovascular, and immune-related diseases.

HBOT and Aging: Slowing the Clock with Oxygen Aging isn’t just about what you see in the mirror—it’s a cellular process driven by oxidative stress, immune senescence, DNA damage, and telomere shortening. Telomeres, the protective caps at the end of chromosomes, naturally shorten with age. When they become critically short, cells can no longer divide and function properly—contributing to aging and age-related diseases. Hyperbaric Oxygen Therapy (HBOT) has emerged as one of the few clinically demonstrated interventions capable of lengthening telomeres and reversing cellular aging markers. Landmark Study: Telomere Lengthening and Immune Rejuvenation A 2020 prospective clinical trial published in Aging (by Hachmo et al.) investigated HBOT’s impact on healthy aging. In this study:

35 healthy adults aged 64+ received HBOT five days a week for 60 sessions at 2.0 ATA with 100% oxygen.

Senescent (non-functional) immune cells decreased by 10–37%, indicating a reversal of immune aging (immunosenescence).

Blood tests before, during, and after treatment showed telomere elongation of up to 38% in specific immune cell populations.

These findings are profound: HBOT not only slowed aging—it reversed molecular markers of aging in immune cells.

Mechanisms of Action The anti-aging effects of HBOT are likely due to repeated, intermittent exposure to high oxygen levels, which trigger a unique adaptive response called the hyperoxic-hypoxic paradox. This paradox stimulates:

Telomerase activity, contributing to telomere length maintenance

Cellular repair, antioxidant defense,

Hypoxia-inducible factors (HIFs) and reactive oxygen species (ROS) in a controlled manner

and stem cell proliferation

What This Means for You At Longevity Medical Institute, we integrate these cutting-edge findings into our anti-aging HBOT protocols. Our personalized longevity programs use HBOT to:

Support genomic stability and cellular youthfulness

Enhance resilience of the immune system

Complement NAD+, mitochondrial peptides, and senolytic therapies

Improve cognitive performance and cardiovascular fitness

Combined with diagnostics and biologically matched therapies, HBOT offers a non-invasive, clinically supported way to slow and potentially reverse aspects of biological aging.

HBOT Protocols at Longevity Medical Institute

All HBOT sessions are customized based on your goals, clinical needs, and diagnostics.

Regenerative Medicine & Stem Cells Post-IV or Injection of Stem Cells: 15–20 sessions to support stem cell engraftment and paracrine signaling.

Benefits: Boosts circulating stem/progenitor cells (CD34+), improves tissue repair in joints, brain, heart, and more.

Anti-Aging & Longevity Initial phase: 2-3x/week for 4-6 weeks at 1.3–1.5 ATA

Maintenance: 1–2x/week ongoing

Benefits: Promotes telomere lengthening, collagen formation, brain oxygenation, and longevity signaling pathways.

Inflammation & Pain Protocol: 1.5 ATA, 3-4x/week for 4–6 weeks Benefits: Downregulates inflammatory cytokines, relieves joint and muscle pain, improves mobility.

Autoimmune Support Protocol: 1.3–1.5 ATA, 3-4x/week for 6–8 weeks

Benefits: Modulates immune response, supports tissue regeneration, improves fatigue and joint function.

Brain Optimization & Neurological Recovery Protocol: 3–5x/week for 6-8 weeks, 1.3–2.0 ATA

Benefits: Enhances neuroplasticity, memory, attention, and speech. Effective for stroke, TBI, concussion, Parkinson’s, ALS, long COVID, and brain fog.

Athletic Recovery & Injury Acute injuries: 2.0 ATA, 90 mins/day for 10–15 sessions

Benefits: Accelerates soft tissue healing, reduces inflammation, improves mitochondrial output and lactic acid clearance.

Chronic rehab: 1.5 ATA, 60 mins, 3x/week

Other Common Applications

Post-viral recovery & long COVID

02 Diabetic ulcers & wound healing

03 Fertility support (both sexes)

04 Cancer support (adjunct to oxygen-sensitive tumors)

05 Fibromyalgia & chronic fatigue

06 Addiction recovery and neurological reset

Why Choose HBOT at Longevity Medical Institute?

Three seated multiplace chambers – no confinement or lying down

Relaxed environment – breathe, meditate, read, or just decompress

Designed for synergy – integrates with stem cells, peptides, exosomes, IVs, and ozone

Personalized protocols – matched to your biology and goals

Reliable results – improvements in energy, cognition, sleep, healing, and inflammation

How HBOT Complements Regenerative Therapies at Longevity Medical Institute At Longevity Medical Institute, we don’t view HBOT as a standalone therapy—it’s a foundational accelerator for the body’s response to advanced regenerative treatments. Our clinical protocols integrate HBOT alongside stem cells, exosomes, peptides, IV nutrients, and more. Here’s why it works so well:

01 Prepares the Body for Stem Cells & Exosomes HBOT increases the vascular microenvironment and enhances oxygenation in tissues—creating a more receptive terrain for cell-based therapies. Studies have shown that HBOT boosts endothelial growth factors, improves perfusion, and increases stem cell homing and engraftment potential.

02 Stimulates Your Own Stem Cells Even before cell therapy, HBOT alone has been shown to mobilize CD34+ progenitor cells from the bone marrow. This naturally boosts the body’s regenerative capacity, aiding in joint, neurological, and soft tissue repair.

03 Enhances Mitochondrial Function Both peptide therapy and IV nutrient protocols depend on cellular energy production (ATP). HBOT improves mitochondrial efficiency, making cells more responsive to interventions like NAD+, B-vitamins, and mitochondrial peptides (e.g., MOTS-c, SS-31). 04 Reduces Inflammation and Immune Stress HBOT downregulates inflammatory cytokines and reduces oxidative stress—amplifying the effects of anti-inflammatory IVs, ozone therapy, or biologics. It also helps rebalance immune activity, complementing therapies aimed at autoimmune regulation.

Accelerates Recovery and Integration After treatment, the body needs time and resources to integrate results. HBOT accelerates tissue healing, lymphatic drainage, detoxification, and mental clarity—creating space for recovery while reinforcing the benefits of every other therapy we offer.

In short: HBOT doesn’t just add to your results—it multiplies them.

Whether you're undergoing a full-body cellular restoration, healing from a chronic condition, or just beginning your wellness journey, HBOT enhances your body's receptivity, responsiveness, and regenerative power.

Oxygen Is Your Oldest Medicine. We Just Deliver It Better. Whether you’re pursuing longevity, recovering from injury or illness, or enhancing performance, HBOT taps into your body’s innate intelligence—fueling it with oxygen where it needs it most.

You sit. You breathe. Your body heals.

Footnotes

Thom, S.R. Hyperbaric Oxygen: Its Mechanisms and Efficacy. Plast Reconstr Surg. 2011;127 Suppl 1:131S–141S.

Read Study

01 Dovemed. Understanding the Principles of Hyperbaric Oxygen Therapy.

Important Disclosure In San Jose del Cabo (B.C.S), Mexico, where we conduct these treatments, our clinic operates under the regulatory oversight of COFEPRIS (Comisión Federal para la Protección contra Riesgos Sanitarios), which is Mexico's equivalent of the U.S. Food and Drug Administration (FDA). COFEPRIS ensures the safety, efficacy, and quality of medical treatments and healthcare practices. Our clinic is licensed by COFEPRIS, guaranteeing that our treatments meet the highest standards of safety and efficacy. While our stem cell and other therapies are approved by COFEPRIS, they are not approved by the U.S. Food and Drug Administration (FDA). Patients considering these treatments should be aware of this distinction. As with any medical treatment, there are risks involved, and individual outcomes may vary. It is important to consult with your physician, thoroughly research the therapies, and carefully consider these risks before undergoing any stem cell or regenerative therapy. Disclaimer The information provided on this site is for informational purposes only and should not be considered medical advice. This site is not intended for the promotion or solicitation of services to audiences where such promotion may conflict with local regulations, including the United States and Canada. If you have questions or concerns about your health, please consult a qualified healthcare professional. All therapies and treatments discussed are subject to applicable laws and regulations and may not be available in all regions. We encourage all patients to conduct their own research, consult with their healthcare providers, and make informed decisions based on the best available information.

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