HBOT and Aging: Slowing the Clock with Oxygen Aging isn’t just about what you see in the mirror—it’s a cellular process driven by oxidative stress, immune senescence, DNA damage, and telomere shortening. Telomeres, the protective caps at the end of chromosomes, naturally shorten with age. When they become critically short, cells can no longer divide and function properly—contributing to aging and age-related diseases. Hyperbaric Oxygen Therapy (HBOT) has emerged as one of the few clinically demonstrated interventions capable of lengthening telomeres and reversing cellular aging markers. Landmark Study: Telomere Lengthening and Immune Rejuvenation A 2020 prospective clinical trial published in Aging (by Hachmo et al.) investigated HBOT’s impact on healthy aging. In this study:
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35 healthy adults aged 64+ received HBOT five days a week for 60 sessions at 2.0 ATA with 100% oxygen.
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Senescent (non-functional) immune cells decreased by 10–37%, indicating a reversal of immune aging (immunosenescence).
Blood tests before, during, and after treatment showed telomere elongation of up to 38% in specific immune cell populations.
These findings are profound: HBOT not only slowed aging—it reversed molecular markers of aging in immune cells.
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