Clinical Benefits & The Löwenstein Difference

S A N T È • LÖW E N S T E I N S L E E P T H E R A PY D E V I C E S

Appendix 3

technology

Study Hunter: Benchtest of AHI agreement in APAP (20A) Benchtest Evaluation of AHI agreement between PAP algorithm and polygraph in predominant CSA patients Y. Rétory; S. Liu; S. Hardy; F. Cottin; G. Roisman, M. Petitjean; Poster presentation ERS 2019. Background: A reliable event detection is the prerequisite to treat sleep disordered breathing efficiently, the major parameter being the apnea-hypopnea-index (AHI). A correctly detected AHI is as well essential for an effective intervention based on the device software and especially based on telemonitoring. It is known that there are differences in detecting and scoring methods between the devices of different manufacturers that might significantly influence the patients’ therapy. In this benchtest by ALEHOS the AHI detected by different devices have been compared to the data measured by a polygraph and scored according to AASM to evaluate the reliability of apnea-hypopnea detection as well as to visualize the differences. Overall Message: Switching from one APAP-device to another without further PG control might have significant consequences on the patients’ therapy due to very different accuracy levels of AHI scoring. Main Results: Even though there was a high correlation between AHI detected by the different devices and detected by the PG overall, there are differences in AHI scoring between the tested devices. AHI generated by the device may not be an absolute indicator of treatment efficiency in patients with suspicious CSA, but prisma20A shows the highest accuracy level (together with Philips dreamstation) of 96% with PG as reference. Resmed and Sefam reached an accuracy level of 84% and 88% respectively. Overall apnea detection of PAP devices correlated better to the results by PG than hypopnea detection of PAP devices. Method: • 25 breathing sequences measured on 4 central sleep apnoea (CSA)patients • Simulated on an artificial lung • on 4 devices that have been compared: AirSense 10 (Resmed), Dreamstation Auto (Philips), S.Box (Sefam), prisma20A (Löwenstein)

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