Research Report 2019_20

Introduction ............................................................................ 4

Foundational Genomics . ....................................................... 6 Greg Barsh, MD, PhD and lab. ............................................................. 8 Thomas May, PhD and lab ............................................................. 10 Human Health Research ..................................................... 12 Richard Myers, PhD and lab............................................................... 14 Sara Cooper, PhD and lab. ................................................................. 16 Devin Absher, PhD and lab................................................................. 18 Greg Cooper, PhD and lab.................................................................. 20 David Bick, MD and The Smith Family Clinic for Genomic Medicine... 22 Elaine Lyon, PhD and the HudsonAlpha Clinical Services Lab. ....... 24 Agriscience Research . ........................................................ 26 Jane Grimwood, PhD, Jeremy Schmutz and the HGSC. .................... 28 Kankshita Swaminathan, PhD and lab............................................... 30 Josh Clevenger, PhD and lab. ............................................................ 34 Alex Harkess, PhD and lab ............................................................ 36 Supporting the Institute ...................................................... 38 The HudsonAlpha Health Alliance .................................................. 40 Jian Han, MD, PhD and public and private collaboration ................ 42 COVID-19 and the HudsonAlpha campus innovators response . ...... 44 Neil Lamb, PhD and Educational Outreach .................................... 46 Shawn Levy, PhD and HudsonAlpha Discovery................................... 52

HudsonAlpha Faculty .......................................................... 54

References . .......................................................................... 63

Adjunct Faculty and Scientific Advisory Board . ............... 64

HudsonAlpha 2019-2020 in Review ................................... 66

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