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The NIOSH Hazardous Drug List
Table 2 NIOSH List of Hazardous Drugs in Healthcare Settings 2024 Table 1 *Drugs identi- fied as IARFC Group2B “possibly carcinogenic to humans “ or as NTP “reasonably anticipated “rea- sonably anticipated to be a human carcinogen” are listed on Table 1 because they have MSHI. Table 2 NIOSH List of Hazardous Drugs in Healthcare Settings 2024 contains one or more of the criteria that meet the NIOSH definition of a haz- ardous drug, and • Do not have MSHI. • Are not classified by the NTP as “known to be a human carcinogen.” • Are not classified by the IARC as Group 1 “carcinogenic to humans” or Group 2A “probably carcinogenic to humans.”
Some of the medications in Table 2 may pos- sess adverse developmental and or reproductive effects. Some of these drugs may also present an occupational hazard to those workers who are actively trying to conceive, who are pregnant or may become pregnant, and who are breastfeeding because the drugs may be excreted in breast milk. Drugs reviewed for the 2024 update were new drug approvals or received new safety-related warn- ings from FDA in the period from January 2014 through December 2015. Drugs underlined and in red font were added on the 2024 List update.’ Refer to Table 3 NIOSH List of Hazardous Drugs In Healthcare Settings 2024-Table 2 . **Previously Table 3. Group 3: Non-antineoplastic drugs that primarily have adverse reproductive effects.
Table 3 NIOSH List of Hazardous Drugs in Healthcare Settings 2024 - Table 2
Drug
AHFS Classification
Biologic License Application
Only Developmental and/or Repro- ductive Hazard**
abacavir
HIV nucleoside and nucleotide reverse transcriptase inhibitors
No
No
abiraterone
Antineoplastic agents "Skin and mucous membrane agents, miscellaneous" Antineoplastic agents
No No
Yes Yes
acitretin
afatinib
No
No No
alefacept
"Skin and mucous membrane agents, miscellaneous. Immunosuppressive agents"
Yes
alitretinoin
"Skin and mucous membrane agents, miscellaneous" "Vasodilating agents. Vasodilating agents, miscellaneous"
No
Yes
ambrisentan
No
Yes
anastrozole apomorphine
Antiestrogens; antineoplastic agents Nonergot- derivative dopamine receptor agonists
No No No No
Yes
No
axitinib
Antineoplastic agents
No No
bexarotene
"Antineoplastic agents; skin and mucous membrane agents, miscellaneous"
bicalutamide
Antineoplastic agents
No
No
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