While Function Health offers an impressive consumer wellness platform measuring approximately 105 direct biomarkers, the Longevity Medical Institute® Longevity Panel measures approximately 125 direct biomarkers and provides a broader, more clinically complete picture of health. Longevity Medical Institute® goes beyond general wellness screening by including deeper clinical categories such as coagulation, infectious disease exposure, preventative oncology markers, stool occult blood screening, advanced hormone evaluation, cardiovascular risk, inflammation, liver and kidney function, urinalysis, thyroid function, and regenerative medicine readiness. The key difference is clinical depth. Function Health is designed primarily as a consumer-facing health tracking platform. Longevity Medical Institute® is designed as a physician-guided longevity and regenerative medicine evaluation, built to help identify risk earlier, personalize care more precisely, and support advanced treatment planning. For patients seeking more than a dashboard, the Longevity Medical Institute® Longevity Panel offers a more comprehensive, medically sophisticated foundation for prevention, optimization, and long-term health strategy.
LMI Longevity Panel vs Function Health
Complete grouped comparison of direct measured biomarkers/tests
This comparison uses the uploaded Function Health patient report and the LMI sample lab report. Calculated ratios, derived scores, and dashboard analytics are excluded so the table reflects direct laboratory measurements and diagnostic outputs.
HEMATOLOGY / COMPLETE BLOOD COUNT
Test / Biomarker
Function Health LMI
Why It Matters
Red Blood Cell Count (RBC)
Included
Included
Evaluates oxygen-carrying cell volume and anemia risk.
Hemoglobin
Included
Included
Measures oxygen transport capacity and can help detect anemia.
Hematocrit
Included
Included
Reflects red blood cell concentration and hydration status.
Mean Corpuscular Volume (MCV)
Included
Included
Helps classify anemia type and red blood cell size patterns.
Mean Corpuscular Hemoglobin (MCH)
Included
Included
Assesses hemoglobin content per red blood cell.
Mean Corpuscular Hemoglobin Concentration (MCHC)
Included
Included
Helps identify iron-related or red cell disorders.
Red Cell Distribution Width (RDW)
Included
Included
Detects variation in red blood cell size, often linked to anemia or inflammation.
Platelet Count
Included
Included
Evaluates clotting capacity and inflammatory activity.
Mean Platelet Volume (MPV)
Included
Included
Reflects platelet activity and potential cardiovascular or inflammatory risk.
White Blood Cell Count (WBC)
Included
Included
Screens immune activity, infection, inflammation, or immune suppression.
Neutrophils
Included
Included
Key immune cells for bacterial defense and acute inflammation.
Lymphocytes
Included
Included
Important for viral defense, immune memory, and adaptive immunity.
Monocytes
Included
Included
Reflect chronic inflammation, immune activation, and tissue repair activity.
Eosinophils
Included
Included
Associated with allergies, asthma, parasites, and inflammatory responses.
Basophils
Included
Included
Involved in allergic and inflammatory signaling.
Band Neutrophils
Not Included
Included
Can indicate acute infection, inflammation, or bone marrow response.
Erythrocyte Sedimentation Rate (ESR)
Not Included
Included
Measures generalized inflammation and can support autoimmune or chronic disease evaluation.
BLOOD TYPE
Test / Biomarker
Function Health LMI
Why It Matters
ABO Blood Type
Included
Included
Identifies blood group compatibility for transfusion and emergency care.
Rhesus Factor (Rh Factor)
Included
Included
Important for transfusion safety and pregnancy compatibility.
AUTOIMMUNE / INFLAMMATION
Test / Biomarker
Function Health LMI
Why It Matters
Antinuclear Antibody Screen (ANA)
Included
Included
Screens for systemic autoimmune activity and connective tissue disease risk.
Rheumatoid Factor (RF)
Included
Included
Helps evaluate rheumatoid arthritis and inflammatory joint disease.
High-Sensitivity C-Reactive Protein (hs-CRP)
Included
Included
Measures low-grade inflammation associated with cardiovascular disease and aging.
Thyroid Peroxidase Antibodies (TPO Antibodies)
Included
Not Included Detects autoimmune thyroid disease, including Hashimoto-type thyroid inflammation.
Thyroglobulin Antibodies
Included
Not Included Helps identify autoimmune thyroid inflammation and thyroid tissue immune activity.
ELECTROLYTES / MINERALS
Test / Biomarker
Function Health LMI
Why It Matters
Sodium
Included
Included
Regulates hydration, blood pressure, and nerve function.
Potassium
Included
Included
Critical for heart rhythm, nerve signaling, and muscle function.
Chloride
Included
Included
Supports fluid balance and acid-base regulation.
Carbon Dioxide / Bicarbonate
Included
Not Included Reflects metabolic acid-base status and respiratory or kidney compensation.
Calcium
Included
Included
Supports bone strength, nerve transmission, muscle function, and cardiac signaling.
Magnesium
Included
Included
Supports cardiovascular, muscular, neurological, and energy metabolism function.
Phosphorus
Not Included
Included
Important for bone health, kidney function, and cellular energy metabolism.
Zinc
Included
Not Included Supports immunity, hormone production, wound healing, and antioxidant defense.
ENVIRONMENTAL TOXINS
Test / Biomarker
Function Health LMI
Why It Matters
Lead
Included
Not Included Screens for toxic exposure affecting brain, cardiovascular, kidney, and blood health.
Mercury
Included
Not Included Evaluates heavy metal exposure linked to neurological and oxidative stress.
CARDIOVASCULAR / LIPIDS
Test / Biomarker
Function Health LMI
Why It Matters
Total Cholesterol
Included
Included
Provides a broad marker of cholesterol metabolism and cardiovascular risk context.
LDL-Cholesterol
Included
Included
Traditional marker of plaque risk and cholesterol transport burden.
HDL-Cholesterol
Included
Included
Protective cholesterol marker involved in reverse cholesterol transport.
Triglycerides
Included
Included
Associated with insulin resistance, fatty liver risk, and cardiovascular disease.
Non-HDL Cholesterol
Included
Not Included Reflects cholesterol carried by potentially atherogenic particles.
Apolipoprotein B (ApoB)
Included
Included
Strong marker of total plaque-forming lipoprotein particle burden.
Apolipoprotein A1 (ApoA1)
Not Included
Included
Reflects protective HDL-related lipoprotein function.
Lipoprotein(a) [Lp(a)]
Included
Included
Genetic cardiovascular risk marker linked to heart attack, stroke, and aortic valve disease.
Test / Biomarker
Function Health LMI
Why It Matters
Homocysteine
Included
Included
Associated with vascular risk, methylation status, and cognitive health.
LDL Particle Number
Included
Not Included Refines cardiovascular risk by estimating the number of LDL particles.
Small LDL Particles
Included
Not Included Small dense LDL particles are more strongly associated with plaque formation.
Medium LDL Particles
Included
Not Included Adds detail to cardiovascular particle risk and lipoprotein patterning.
LDL Peak Size
Included
Not Included Helps characterize LDL particle pattern and cardiometabolic risk.
LDL Pattern
Included
Not Included Identifies more or less atherogenic LDL particle patterns.
Large HDL Particles
Included
Not Included Reflects HDL particle quality and protective function.
Very Low-Density Lipoprotein Cholesterol (VLDL)
Not Included
Included
Reflects triglyceride-rich lipoprotein burden and metabolic risk.
D-Dimer
Not Included
Included
Screens for abnormal clotting activity and thrombotic risk.
Creatine Phosphokinase (CPK)
Not Included
Included
Indicates muscle injury, intense training load, or cardiac strain.
Lactate Dehydrogenase (LDH)
Not Included
Included
Broad marker of tissue damage, cellular turnover, and systemic stress.
KIDNEY FUNCTION
Test / Biomarker
Function Health LMI
Why It Matters
Blood Urea Nitrogen (BUN)
Included
Included
Evaluates kidney function, hydration status, and protein metabolism.
Creatinine
Included
Included
Standard kidney filtration marker influenced by muscle mass and renal function.
Estimated Glomerular Filtration Rate (eGFR)
Included
Included
Estimates kidney filtration efficiency and chronic kidney disease risk.
Uric Acid
Included
Included
Associated with gout, metabolic disease, kidney stress, and cardiovascular risk.
Random Urine Albumin
Included
Included
Detects early kidney or vascular damage, especially in diabetes and hypertension.
LIVER FUNCTION
Test / Biomarker
Function Health LMI
Why It Matters
Alanine Aminotransferase (ALT)
Included
Included
Sensitive marker of liver inflammation, fatty liver, or hepatocellular injury.
Aspartate Aminotransferase (AST)
Included
Included
Reflects liver, muscle, or systemic tissue injury.
Gamma-Glutamyl Transferase (GGT)
Included
Included
Marker of liver stress, oxidative burden, and detoxification demand.
Alkaline Phosphatase (ALP)
Included
Included
Evaluates liver, bile duct, and bone health.
Total Bilirubin
Included
Included
Reflects liver processing function and red blood cell breakdown.
Direct Bilirubin
Not Included
Included
Helps distinguish types of bilirubin elevation and bile flow issues.
Indirect Bilirubin
Not Included
Included
Helps evaluate red blood cell turnover and liver handling.
Albumin
Included
Included
Reflects liver production, nutritional status, and inflammatory balance.
Globulin
Included
Included
Reflects immune protein activity and inflammatory patterns.
Total Protein
Included
Included
Measures overall protein balance, nutrition, and liver/immune status.
PANCREAS / DIGESTIVE ENZYMES
Test / Biomarker
Function Health LMI
Why It Matters
Amylase
Included
Not Included Helps assess pancreatic digestive enzyme activity.
Lipase
Included
Included
Helps evaluate pancreatic inflammation or dysfunction.
HORMONES / MEN'S HEALTH
Test / Biomarker
Function Health LMI
Why It Matters
Total Testosterone
Included
Included
Measures overall androgen production and hormone status.
Free Testosterone
Included
Included
Reflects biologically active testosterone available to tissues.
Sex Hormone Binding Globulin (SHBG)
Included
Included
Determines testosterone availability and hormone transport.
Estradiol
Included
Included
Important for bone, cardiovascular, libido, and hormone balance.
Follicle Stimulating Hormone (FSH)
Included
Included
Assesses pituitary and reproductive signaling.
Luteinizing Hormone (LH)
Included
Included
Regulates testosterone production and reproductive signaling.
Prolactin
Included
Included
Elevated levels can affect libido, fertility, and pituitary health.
Dehydroepiandrosterone Sulfate (DHEA-S)
Included
Included
Adrenal hormone associated with vitality, resilience, and aging.
Dehydroepiandrosterone (DHEA)
Not Included
Included
Provides additional adrenal hormone assessment.
Dihydrotestosterone (DHT)
Not Included
Included
Important for prostate, hair, and androgen metabolism.
Progesterone
Not Included
Included
Helps assess broader sex hormone balance.
Prostate Specific Antigen, Total (PSA Total)
Included
Included
Screens prostate enlargement, inflammation, and cancer risk.
Prostate Specific Antigen, Free (PSA Free)
Included
Included
Improves prostate risk interpretation when total PSA is elevated.
METABOLIC / DIABETES
Test / Biomarker
Function Health LMI
Why It Matters
Glucose
Included
Included
Core marker of blood sugar regulation and metabolic health.
Hemoglobin A1c (HbA1c)
Included
Included
Reflects average blood sugar exposure over approximately three months.
Insulin
Included
Included
Helps detect insulin resistance before diabetes develops.
Leptin
Included
Not Included Hormone involved in appetite, fat signaling, and metabolic regulation.
VITAMINS / NUTRITION / IRON
Test / Biomarker
Function Health LMI
Why It Matters
Vitamin D
Included
Included
Supports bone, immune, hormone, and inflammatory health.
Vitamin B12
Included
Included
Important for nerves, blood cells, cognition, and methylation.
Test / Biomarker
Function Health LMI
Why It Matters
Methylmalonic Acid (MMA)
Included
Not Included Sensitive marker of functional vitamin B12 deficiency.
Ferritin
Included
Included
Reflects iron storage and can rise with inflammation.
Iron
Included
Included
Measures circulating iron available for oxygen transport and metabolism.
Iron Saturation
Included
Not Included Helps evaluate iron deficiency or overload.
Total Iron Binding Capacity (TIBC)
Included
Not Included Measures iron transport capacity and helps interpret iron status.
Omega-3 Index / OmegaCheck
Included
Not Included Measures anti-inflammatory omega-3 status linked to cardiovascular and brain health.
Omega-3 EPA
Included
Not Included Cardiovascular and anti-inflammatory fatty acid.
Omega-3 DHA
Included
Not Included Supports brain, eye, and cell membrane health.
Omega-3 DPA
Included
Not Included Reflects additional omega-3 reserve status.
Omega-3 Total
Included
Not Included Measures total omega-3 fatty acid status.
Omega-6 Linoleic Acid
Included
Not Included Reflects dietary omega-6 intake and inflammatory balance.
Omega-6 Arachidonic Acid
Included
Not Included Involved in inflammatory signaling and cardiometabolic balance.
Omega-6 Total
Included
Not Included Measures total omega-6 fatty acid status.
STRESS / ADRENAL
Test / Biomarker
Function Health LMI
Why It Matters
Cortisol
Included
Included
Primary stress hormone affecting metabolism, energy, inflammation, and aging.
THYROID
Test / Biomarker
Function Health LMI
Why It Matters
Thyroid Stimulating Hormone (TSH)
Included
Included
Master thyroid regulatory hormone.
Free Thyroxine (Free T4)
Included
Included
Measures available thyroid hormone for metabolic conversion.
Free Triiodothyronine (Free T3)
Included
Included
Measures active thyroid hormone related to energy and metabolism.
Total Thyroxine (Total T4)
Not Included
Included
Adds broader thyroid hormone assessment.
Total Triiodothyronine (Total T3)
Not Included
Included
Adds broader thyroid hormone assessment.
Thyroglobulin
Not Included
Included
Useful in thyroid evaluation and surveillance.
Protein-Bound Iodine
Not Included
Included
Reflects iodine-bound thyroid hormone status.
Thyroid Peroxidase Antibodies
Included
Not Included Detects autoimmune thyroid inflammation.
Thyroglobulin Antibodies
Included
Not Included Helps identify autoimmune thyroid disease.
URINALYSIS
Test / Biomarker
Function Health LMI
Why It Matters
Urine Color
Included
Included
Basic hydration and urine quality indicator.
Urine Appearance / Clarity
Included
Included
Screens for abnormal sediment, infection, or concentration.
Urine Specific Gravity
Included
Included
Measures hydration and kidney concentrating ability.
Urine pH
Included
Included
Reflects urinary chemistry and metabolic balance.
Urine Glucose
Included
Included
Screens for abnormal glucose spilling into urine.
Urine Ketones
Included
Included
Indicates fat metabolism or diabetic metabolic stress.
Urine Protein
Included
Included
Screens for kidney stress or damage.
Urine Albumin
Included
Included
Early kidney and vascular damage marker.
Urine Bilirubin
Included
Included
May suggest liver or bile flow abnormalities.
Urine Occult Blood / Hemoglobin
Included
Included
Detects hidden urinary bleeding.
Nitrites
Included
Included
Suggests bacterial urinary tract infection.
Leukocyte Esterase
Included
Included
Indicates urinary inflammation or infection.
Urine Red Blood Cells / Erythrocytes
Included
Included
Screens for bleeding or kidney/urinary tract disease.
Urine White Blood Cells / Leukocytes
Included
Included
Indicates urinary inflammation or infection.
Bacteria
Included
Included
Screens for urinary infection or contamination.
Hyaline Casts / Casts
Included
Included
May indicate kidney stress or urinary sediment.
Squamous Epithelial Cells / Epithelial Cells
Included
Included
Helps interpret urine contamination or epithelial shedding.
Pus Cells
Not Included
Included
Supports infection or urinary inflammation assessment.
Bacterial Cytolysis
Not Included
Included
Can indicate bacterial breakdown in urine sediment.
Mucus
Not Included
Included
May reflect irritation, inflammation, or contamination.
Crystals
Not Included
Included
Can indicate stone risk or urinary chemistry imbalance.
Yeasts
Not Included
Included
Screens for possible fungal urinary contamination or infection.
Urobilinogen
Not Included
Included
Helps assess liver and hemolysis-related conditions.
STOOL / GASTROINTESTINAL SCREENING
Test / Biomarker
Function Health LMI
Why It Matters
Fecal Occult Blood (FOB)
Not Included
Included
Screens for hidden gastrointestinal bleeding, colon cancer risk, ulcers, and polyps.
COAGULATION
Test / Biomarker
Function Health LMI
Why It Matters
Prothrombin Time (PT)
Not Included
Included
Evaluates clotting function through the extrinsic pathway.
International Normalized Ratio (INR)
Not Included
Included
Standardizes PT for clotting risk interpretation.
Activated Partial Thromboplastin Time (aPTT/PTT)
Not Included
Included
Evaluates intrinsic clotting pathway and bleeding risk.
CANCER / TUMOR MARKERS
Test / Biomarker
Function Health LMI
Why It Matters
Carcinoembryonic Antigen (CEA)
Not Included
Included
Tumor marker associated with gastrointestinal and other cancers.
Alpha-Fetoprotein (AFP)
Not Included
Included
Tumor marker used in liver and germ cell cancer screening.
Beta Human Chorionic Gonadotropin (beta-hCG)
Not Included
Included
Tumor marker associated with germ cell tumors and endocrine patterns.
INFECTIOUS DISEASE
Test / Biomarker
Function Health LMI
Why It Matters
Borrelia burgdorferi IgG Antibodies
Not Included
Included
Screens for prior Lyme disease exposure.
Borrelia burgdorferi IgM Antibodies
Not Included
Included
Screens for recent or active Lyme immune response.
Epstein-Barr Virus Nuclear Antigen IgG
Not Included
Included
Indicates prior EBV exposure and immune memory.
Epstein-Barr Virus Viral Capsid Antigen IgG
Not Included
Included
Helps assess previous EBV infection.
Epstein-Barr Virus Viral Capsid Antigen IgM
Not Included
Included
May indicate recent or active EBV infection.
Final Clinical Comparison Conclusion
Panel
Approximate Direct Measured Biomarkers / Tests
Function Health uploaded report
Approximately 105 direct measured biomarkers/tests
LMI Longevity Panel
Approximately 125 direct measured biomarkers/tests
Overall Clinical Positioning Function Health is best described as a consumer-focused longevity optimization platform built around preventative wellness analytics, broad population screening, and patient engagement. The LMI Longevity Panel is best described as a physician-grade clinical longevity and regenerative medicine panel with broader medical depth, stronger systems-based screening, and better alignment with preventative and regenerative medicine practice. Function Health Strengths Function Health is strongest in advanced lipid particle analysis, environmental toxin screening, omega fatty acid profiling, functional nutrition assessment, and consumer-friendly dashboards. Its lipid particle testing can add cardiovascular refinement in insulin resistance, metabolic syndrome, and discordant lipid patients. Its omega fatty acid and heavy metal testing add useful dimensions that are not fully captured by standard chemistry, hormone, or cardiovascular panels. LMI Longevity Panel Strengths The LMI panel is stronger clinically because it extends beyond wellness optimization into coagulation, infectious disease assessment, preventative oncology, stool blood screening, expanded hormonal evaluation, tissue injury markers, inflammatory screening, and regenerative medicine readiness. This gives LMI a broader physician-grade view of patient risk before advanced therapies such as stem cells, exosomes, peptides, HBOT, and hormone optimization. Cardiovascular Interpretation Function Health has more lipid particle detail, including LDL particle number and subfractions. However, LMI already measures several of the most clinically actionable cardiovascular markers, including ApoB, ApoA1, Lp(a), hs-CRP, homocysteine, D-Dimer, triglycerides, HDL, LDL, and VLDL. Because ApoB already captures much of the plaque-forming particle burden, LDL particle number would add refinement rather than a completely new risk domain. Strategic Takeaway Function Health is optimized for wellness analytics, longitudinal tracking, advanced lipid refinement, and consumer engagement. LMI is optimized for physician-grade preventative medicine, regenerative medicine screening, oncology awareness, infectious disease burden, coagulation safety, endocrine optimization, gastrointestinal screening, and broader clinical decision-making. Overall, LMI measures more direct tests and has greater medical depth, while Function Health has useful advantages in omega fatty acids, heavy metals, functional B12 assessment, leptin, and advanced lipid particle detail.
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