A System-by-System Comparison Function Health vs Longevity Medical Institute Advanced Panel Every major body system, side by side — compared not by how many markers each measures, but by the clinical questions each answers and the value its markers deliver. A panel is only as good as the clinical questions it answers. Across every system below, we show what each panel measures and — more importantly — what that coverage means clinically. The badge marks where each panel is deeper, or where they are evenly matched. This is not a contest of marker counts. Function Health is excellent at advanced risk characterization and prevention — LDL particle analysis, fatty-acid balance, micronutrient depth, toxins, and a biological-age estimate. The Longevity Medical Institute's Advanced Panel pairs a solid risk foundation with the biology of active disease and a full clinical workup — vascular inflammation, cardiac strain, coagulation, a deeper hormone and thyroid picture, cancer screening, and EBV/Lyme immune history — all interpreted together by a physician. Put simply: Function is built to tell you your long-term risk; the LMI panel is built to tell you your risk and what is happening in your body now.
COMPLETE LAB PANEL COMPARISON
A System-by-System Comparison Function Health vs LMI Advanced Panel Every major body system, side by side — compared not by how many markers each measures, but by the clinical questions each answers and the value its markers deliver.
Both are deep, multi-system panels. Each is built to excel at different questions: Function for advanced risk characterization and prevention; the LMI panel for pairing that risk view with the biology of active disease and a full clinical workup.
Longevity Medical Institute San José del Cabo, Mexico · longevity-institute.com
HOW TO READ THIS Value, Not Volume
A panel is only as good as the clinical questions it answers. Across every system below, we show what each panel measures and — more importantly — what that coverage means clinically. The badge marks where each panel is deeper, or where they are evenly matched.
LMI deeper here
Function deeper here
Evenly matched
Cardiovascular
DIFFERENT STRENGTHS
LMI ADVANCED PANEL ApoB · ApoA1 · Lp(a) · Lp-PLA2 · NT-proBNP · D- Dimer · CPK · Total/HDL/LDL/VLDL · Triglycerides · Atherogenic Index
FUNCTION HEALTH ApoB · Lp(a) · LDL Particle Number · LDL Small/Medium · LDL Peak Size & Pattern · HDL Large · Non-HDL · Total/HDL/LDL · Triglycerides
Function goes deeper on risk characterization through LDL particle analysis. LMI adds the biology of active disease — plaque inflammation (Lp-PLA2), cardiac strain (NT-proBNP), and clotting (D-Dimer) — on the same ApoB/Lp(a) foundation.
Inflammation
LMI DEEPER
LMI ADVANCED PANEL hs-CRP · Interleukin-6 (IL-6) · ESR FUNCTION HEALTH hs-CRP Both track systemic inflammation via hs-CRP. LMI adds IL-6 (an upstream inflammatory cytokine) and ESR, giving a broader inflammatory picture.
Metabolic & Glucose
FUNCTION DEEPER
LMI ADVANCED PANEL Glucose · Insulin · HOMA Index · HbA1c FUNCTION HEALTH Glucose · Insulin · HOMA · HbA1c · Leptin Core glucose-metabolism workup is equivalent. Function adds Leptin, an appetite/adiposity signal relevant to metabolic-syndrome characterization.
Kidney Function
EVENLY MATCHED
LMI ADVANCED PANEL Urea · BUN · Creatinine · GFR · Uric Acid FUNCTION HEALTH BUN · Creatinine · eGFR · Uric Acid · Urine Albumin Comparable filtration assessment. Function reports a standalone urine albumin; LMI captures albumin within its full urinalysis.
SYSTEM BY SYSTEM Hormones, Thyroid & Organ Function Hormones & Endocrine
LMI DEEPER
LMI ADVANCED PANEL Total & Free Testosterone · Estradiol · DHEA-S · DHEA · DHT · SHBG · LH · FSH · Prolactin · Progesterone · Cortisol · IGF-1
FUNCTION HEALTH Testosterone · Estradiol · DHEA-S · SHBG · LH · FSH · Cortisol
LMI reaches further into the androgen and growth axis — adding DHT (active androgen), IGF-1 (growth/repair), DHEA (not just the sulfate), and progesterone — for a fuller hormonal- optimization picture. Thyroid LMI DEEPER
LMI ADVANCED PANEL TSH · Total T4 & T3 · Free T4 & T3 · T-Uptake · Free Thyroxine Index · Protein-Bound Iodine · Anti- TPO · Anti-Thyroglobulin
FUNCTION HEALTH TSH · Free T3 · Free T4 · Anti-TPO · Anti- Thyroglobulin
Both screen for autoimmune thyroid disease with antibodies. LMI adds total hormone fractions, T-Uptake, and Free Thyroxine Index for a more complete picture of binding and conversion. Liver & Pancreas LMI DEEPER
LMI ADVANCED PANEL AST · ALT · GGT · ALP · LDH · Total/Direct/Indirect Bilirubin · Total Protein · Albumin · Globulin · Amylase · Lipase
FUNCTION HEALTH AST · ALT · GGT · ALP · Bilirubin · Total Protein · Albumin
Equivalent core liver workup. LMI adds LDH (tissue turnover) plus pancreatic enzymes amylase and lipase, extending the chemistry into pancreatic function. Hematology EVENLY MATCHED
LMI ADVANCED PANEL Full CBC · WBC differential with absolute counts · MCV/MCH/MCHC/RDW · Platelets & MPV · Blood Group/Rh
FUNCTION HEALTH Full CBC · WBC differential with absolute counts · indices · Platelets
Essentially equivalent complete blood counts; both report differentials and absolute counts. LMI also documents blood group and Rh factor.
SYSTEM BY SYSTEM Nutrients, Coagulation & Immune Vitamins & Nutrients FUNCTION DEEPER FUNCTION HEALTH Vitamin D · B12 · Homocysteine · Ferritin · Folate · Methylmalonic Acid · RBC Magnesium · Zinc Both cover the core vitamins tied to energy and methylation. Function reaches deeper into micronutrient status — adding MMA (functional B12), RBC magnesium, and zinc. Fatty Acid Balance FUNCTION ONLY LMI ADVANCED PANEL Vitamin D (25-OH) · Vitamin B12 · Homocysteine · Serum Iron · Ferritin LMI ADVANCED PANEL Not currently measured FUNCTION HEALTH OmegaCheck · Omega-3 EPA/DHA/DPA · Omega-6 Total/Arachidonic/Linoleic · Omega-6:3 & AA/EPA Ratios A genuine Function strength: the omega fatty-acid profile informs cardiometabolic and inflammatory balance — a useful complement for prevention-focused patients. Coagulation LMI ONLY
LMI ADVANCED PANEL Prothrombin Time (PT) · INR · PTT · D-Dimer · Fibrinogen
FUNCTION HEALTH Not measured
LMI assesses clotting function directly — relevant to thrombotic risk, surgical readiness, and active vascular events — a dimension outside Function’s prevention scope. Infectious & Immune History LMI ONLY
LMI ADVANCED PANEL EBV VCA IgG/IgM · EBV EBNA IgG · Anti-Borrelia (Lyme) IgG/IgM
FUNCTION HEALTH Not measured
LMI documents prior/active exposure to Epstein-Barr and Lyme — valuable when chronic- fatigue, post-viral, or tick-borne illness is part of the clinical question. Autoimmunity EVENLY MATCHED FUNCTION HEALTH ANA Pattern Both screen for autoimmune activity with ANA. LMI also reports rheumatoid factor. LMI ADVANCED PANEL ANA (IFA) · Rheumatoid Factor
SYSTEM BY SYSTEM Screening, Toxins & Urinalysis Cancer / Tumor Markers
LMI ONLY
LMI ADVANCED PANEL Total & Free PSA · Free PSA Index · CEA · AFP · CA 19-9 · β-hCG · Fecal Occult Blood
FUNCTION HEALTH Galleri MCED available as paid add-on
LMI includes blood-based tumor markers and FOBT within the panel. Function offers multi- cancer early detection (Galleri) only as a separate paid add-on, not in the base panel.
Environmental Toxins
FUNCTION ONLY
LMI ADVANCED PANEL Not currently measured FUNCTION HEALTH Lead · Mercury Function screens for heavy-metal exposure — a useful environmental dimension for patients with relevant history or symptoms.
Urinalysis
LMI DEEPER
LMI ADVANCED PANEL Full physical-chemical panel · complete microscopy: casts, crystals, bacteria, mucus, epithelial cells, yeast, cells
FUNCTION HEALTH Urine Albumin
LMI performs a complete urinalysis with microscopic sediment — useful for renal, urinary, and infection screening beyond a single albumin measure.
Biological Age
FUNCTION ONLY
LMI ADVANCED PANEL Not currently included FUNCTION HEALTH Biological age estimate Function provides a composite biological-age estimate — an engaging longevity metric, though derived from underlying markers both panels largely share.
THE CLINICAL BOTTOM LINE This is not a contest of marker counts. Function Health is excellent at advanced risk characterization and prevention — LDL particle analysis, fatty-acid balance, micronutrient depth, toxins, and a biological-age estimate. The LMI Advanced Panel pairs a solid risk foundation with the biology of active disease and a full clinical workup — vascular inflammation, cardiac strain, coagulation, a deeper hormone and thyroid picture, cancer screening, and EBV/Lyme immune history — all interpreted together by a physician. Put simply: Function is built to tell you your long-term risk; the LMI panel is built to tell you your risk and what is happening in your body now. Comparison based on one patient’s actual Function Health report against the current LMI Advanced Panel. Function and LMI panels both vary by individual and evolve over time; some Function markers are available only as paid add-ons. For informational purposes only; not medical advice. No single biomarker diagnoses disease on its own. The Longevity Medical Institute Advanced Lab Panel measures 140+ biomarkers across sixteen systems — interpreted by our physicians as one connected picture, pairing long-term risk with the biology of active disease.
VIEW LMI 140+ BIOMARKER PANEL
Longevity Medical Institute San José del Cabo, Mexico · longevity-institute.com
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