ADVANCED PLACEMENT BIOLOGY
BIG IDEA
INVESTIGATION OPTIONS
BIOLOGY
Cat. #345 INVESTIGATION 2 OPTION Exploring the Genetics of Taste: SNP Analysis of the PTC Gene Using PCR
For 25 Reactions. This is a set of five modules that starts with (I) extrac - tion of DNA from buccal cells (II) amplifying the segment that contains the polymorphic nucleotide (III) digestion of the amplified fragment with the restriction enzyme that recognizes the SNP (IV) analysis by gel electro - phoresis (V) tasting the PTC paper to confirm the results obtained.)
Cat. #337 INVESTIGATION 2 OPTION Drosophila Genotyping Using PCR
For 10 Groups. Students will learn about DNA polymorphisms by amplifying DNA regions that vary between wild & mutant Drosophila . Amplified DNA from wild-type and white-eyed flies are separated by agarose gel electrophoresis and analyzed.
Cat. #339-340 INVESTIGATION 3 OPTION Sequencing the Human Microbiome
For 10 Groups. Humans live in a delicate balance with the microorganisms that live in and on their bodies. If this balance is disrupted, harmful bacteria can multiply and cause disease. In this experiment, students will read DNA sequences obtained from automated DNA sequencing techniques. The data will be analyzed using publicly available databases to identify the bacterial species present in a patient sample. The results will be used to make a diagnosis.
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