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2026 EDVOTEK® Resource Guide

GENETIC ENGINEERING & TRANSFORMATION

Cat. #308 Fixing Genes, Fighting Disease: A Hands-On CRISPR Lab

For 6 Groups. TThis DMD CRISPR Simulation Kit introduces students to gene editing by modeling the correction of a Duchenne Muscular Dystrophy (DMD)-like mutation in bacteria. Using CRISPR-based tools, students restore fluorescence to a mutated GFP gene, simulating therapeutic correction of the dystrophin gene.

The hands-on workflow includes DNA ligation, bacterial transforma - tion, and protein extraction, culminating in SDS-PAGE analysis to visu -

alize gene expression differences. Through this process, students learn how genetic mutations disrupt protein production and how CRISPR can reverse these effects. The experiment emphasizes real-world applications of CRISPR in treating human genetic disorders like DMD, providing both molecular biology skills and disease context. This immersive lab bridges fundamental biotechnology with advanced gene therapy concepts in an accessible and engaging way.

Storage: Some Components Require Freezer & Refrigerator Storage Upon Receipt. CLICK HERE For Experiment #308 Components and Requirements.

Cat. #228 Agar Art: Creating Masterpieces with Microbes

Requires 60 minutes (plus two incubations)

For 25 Students. At the intersection of art, science, and technology is Bio-Art, the creation of works of art using living matter. One common way to create Bio-Art uses bacteria transformed with DNA codes for brightly-colored proteins. In this experiment, students create “Bio-Paints” using bacterial culture techniques. The color-producing microbes are painted onto an agar plate canvas. After incubation will inspect, admire, and hopefully share your living art. Includes four brightly colored BioPaints and the material needed for 25 agar canvases.

• CREATE works of art using color-producing microbes. • EXPLORE the intersections of science and art and the field of BioArt. • UNDERSTAND the transformation technologies used to create bacterial BioPaints.