Go Magazine | Issue 57

HEALTH REPORT

The superior benefits of tocotrienols over tocopherols are supported by numerous studies which illustrate tocotrienols’ ability to reduce the risks associated with cardiovascular disease, metabolic syndrome, diabetes, bone injuries, and cancer - as well as promote skin health. Also, annatto-originated tocotrienols have a distinct advantage in lowering cholesterol and enhancing cellular health, without the interference of tocopherols. Are there any contradictions? A crucial concept to grasp when discussing vitamin E is the interference that occurs when we have too much alpha-tocopherol in our system. Alpha-tocopherol is unique because it has an alpha-TTP (alpha- tocopherol transfer protein), as well as the ability to protect LDL from oxidation. Think of the transfer protein as a ‘passport’ that allows alpha-tocopherol to gain admittance and enter the bloodstream. A typical Western diet provides all the alpha- tocopherol we need for it to do this job. The interference occurs when we have too much alpha-tocopherol in our system (for example, taking alpha-tocopherol as a supplement). Our passageways become filled

with these molecules that, because they have the right of way, impede tocotrienols from absorption and entry into the bloodstream. How much alpha-tocopherol is too much? In a healthy diet, it is expected we consume about 10-15 mg of tocopherols per day. Such amounts do not present any interference to tocotrienols. There are no other known contra- indications with tocotrienol outside of alpha-tocopherol. It is synergistic with vitamin C and mixes well with other lipid (fat) nutrients, such as carotenoids, fish oil and CoQ10. What is the best way to take tocotrienol? In order to obtain adequate lipid antioxidant protection, a normal healthy person should take 100-200 mg of tocotrienol per day. The recommended dose for a person with a mild chronic condition is 300-450 mg per day, and for a person with an advanced chronic condition, 450-600 mg per day. Clinical trials indicate that the highest dose taken safely for 24 months is 900 mg per day. Dr Barrie Tan is hailed as the world’s foremost expert on vitamin E. With a PhD in Chemistry/Biochemistry, Dr Tan is committed to the research and development of phytonutrients that reduce and slow chronic disorders.

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